20 . February , 2018 - Tuesday
Check todays hot topics or new products

Find a Drug: Advanced

Please Sign in or Register

All about: Factor Viia

Big Image

Some commonly used brand names are:

In the U.S.—

  • NovoSeven

Other commonly used names are coagulation factor VIIa (recombinant) , eptacog alfa , factor 7 , proconvertin , recombinant activated factor VIIa , recombinant coagulation factor VIIa , recombinant factor VIIa , and rFVIIa.

Not commercially available in Canada.

Category

  • Antihemorrhagic

Description

Factor VIIa is a man-made protein produced to replicate the naturally occurring activated factor VII (factor VIIa) in the body. Factor VIIa is used to stop bleeding of injuries for patients with hemophilia by helping the blood to clot. This man-made protein, factor VIIa, is used in people who have Hemophilia A or Hemophilia B, who have also formed antibodies against other clotting proteins that help bleeding to stop. Patients using factor VIIa are usually male.

Factor VIIa is to be administered only by or under the supervision of your doctor or other health care professional. It is available in the following dosage form(s):

  • Parenteral
  • Injection (U.S.)

Before Using This Medicine

In deciding to use a medicine, the risks of using the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For factor VIIa, the following should be considered:

Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to factor VIIa or to any products that contain mouse, hamster, or cow proteins. Also tell your doctor and pharmacist if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy—Studies on effects in pregnancy have not been done in humans.

Breast-feeding—It is not known whether factor VIIa passes into breast milk. However, because this medicine may cause serious side effects, breast-feeding is generally not recommended while you are receiving it.

Children—This medicine has been tested in children and no side effects or problems were found that were different from those seen in adults.

Older adults—No information is available about the use of factor VIIa in older adults.

Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking factor VIIa, it is especially important that your doctor and pharmacist know if you are taking any of the following:

  • Activated prothrombin complex concentrates (ie, FEIBA, Autoplex T) or
  • Prothrombin complex concentrates (ie, AlphaNine, BeneFix)—May increase the risk of side effects

Other medical problems—The presence of medical problems may affect the use of factor VIIa. Make sure to tell your doctor if you have any medical problems, especially:

  • Blood clots or a history of medical problems caused by blood clots or
  • Heart disease or
  • Infection or
  • Injury (crush)—These conditions may increase the risk of bleeding

Proper Use of This Medicine

This medicine is to be used in a medical setting under the direct supervision of a doctor.

Dosing—The dose of factor VIIa will be different for different patients. The dose you receive will be based on:

  • Your body weight.
  • How much, how often, and where in your body you are bleeding.

Precautions While Using This Medicine

If you notice early signs of a hypersensitivity reaction such as hives, skin rash, tightness of the chest or wheezing, lightheadedness or dizziness, notify your physician immediately.

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common

Bleeding problems; fever; high blood pressure; joint or muscle pain and/or stiffness

Less common or rare

Bloating or swelling of face, hands, lower legs, and/or feet; bluish color hands or feet; blurred vision; changes in facial color; chest pain; chills; cold sweats; confusion; continuing thirst; cough; dizziness; excessive sweating; faintness; fast heartbeat; hives and/or itching; large flat blue or purplish patches on the skin; lightheadedness when getting up from a lying or sitting position; persistent bleeding or oozing from puncture sites or mucous membranes [bowel, mouth, nose, or urinary bladder]; puffiness or swelling of eyelids or around the eyes; shakiness; slurred speech; shortness of breath; skin rash; slow or irregular heartbeat [less than 50 beats per minute]; sneezing; sore throat; sudden decrease in the amount urine; swelling of face, fingers, feet, and/or lower legs; troubled breathing, tightness in chest, and/or wheezing; unusual tiredness or weakness; weight gain (unusual).

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

Less common or rare

Burning or stinging at the injection site; changes in blood pressure or pulse rate; drowsiness; flushing [redness of face]; headache; pinpoint red or purple spots on skin; nausea or vomiting

. Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

Additional Information

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, factor VIIa is used in certain patients with the following medical conditions:

  • Factor VII deficiency

Other than the above information, there is no additional information relating to proper use, precautions, or side effects for this use.

Developed: 05/09/2000

The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products.

Recent Drug Updates at DrugIndexOnline:





Advil Multi-Symptom Cold Advil Multi-Symptom Cold
Generic Name: chlorpheniramine, ibuprofen, and pseudoephedrine (klor fen EER a meen, I byoo PRO fen, soo doh ee FED rin) Brand Names: Advil Allergy Sinus, Advil Childrens Allergy Sinus, Advil Multi-Symptom Cold What is Advil Multi-Symptom Cold (chlorpheniramine, ibuprofen, and pseudoephe more...

Brompheniramine/Pseudoephedrine Sustained-Release Tablets Brompheniramine/Pseudoephedrine Sustained-Release Tablets
Generic Name: Brompheniramine/Pseudoephedrine Sustained-Release Tablets (brome-fen-EER-ah-meen/soo-doe-eh-FED-rin) Brand Name: Examples include Bidhist-D and Lodrane 12DBrompheniramine/Pseudoephedrine Sustained-Release Tablets is used for:Relieving symptoms of sinus congestion, pressure, runny more...

Chlorpromazine Concentrate Chlorpromazine Concentrate
Generic Name: Chlorpromazine Oral Concentrate (klor-PROE-ma-zeen) Brand Name: Generic only. No brands available.Chlorpromazine Concentrate is used for:Treating certain mental or mood disorders (eg, schizophrenia), the manic phase of manic-depressive disorder, anxiety and restlessness before surge more...

Focalin Focalin
Some commonly used brand names are: In the U.S.— Focalin Focalin XR Generic name product may be available in the U.S. Other commonly used names are: D-methylphenidate and Ritadex . † Not commercially available in Canada. Category Central nervous system (CNS) stimulant Desc more...

Forteo Forteo
Generic Name: teriparatide Dosage Form: Injection Warning In male and female rats, teriparatide caused an increase in the incidence of osteosarcoma (a malignant bone tumor) that was dependent on dose and treatment duration. The effect was observed at systemic exposures to teriparatide ranging fr more...

Imovax Rabies Imovax Rabies
Generic Name: rabies vaccine, human diploid cell (RAY beez vax EEN, HYOO man DY ploid sel) Brand Names: Imovax Rabies What is rabies vaccine? Rabies is a serious disease caused by a virus. Rabies is mainly a disease of animals. Humans get rabies when they are bitten by an infected animal more...

Loestrin Fe 1.5/30 Loestrin Fe 1.5/30
Some commonly used brand names are: In the U.S.— Alesse 3 Brevicon 5 Cyclessa 1 Demulen 1/35 2 Demulen 1/50 2 Desogen 1 Estrostep 4 Estrostep Fe 4 Genora 0.5/35 5 Genora 1/35 5 Genora 1/50 6 Intercon 0.5/35 5 Intercon 1/35 5 Intercon 1/50 6 Jenest 5 Levlen 3 Levlite 3 Levora 0.15/30 3 Loe more...

Pheniramine, Pyrilamine, Hydrocodone, Potassium Citrate, and Ascorbic Acid Pheniramine, Pyrilamine, Hydrocodone, Potassium Citrate, and Ascorbic Acid
Some commonly used brand names are: In the U.S.— Alka-Seltzer Plus Cold and Cough 21 Alka-Seltzer Plus Cold and Cough Medicine Liqui-Gels 34 Alka-Seltzer Plus Night-Time Cold Liqui-Gels 35 Ami-Tex LA 69 Anatuss LA 70 Benylin Expectorant 54 Bromfed-DM 17 Broncholate 68 Carbinoxamine Compou more...