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All about: Floxin

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Generic Name: Ofloxacin Tablets (oh-FLOX-uh-SIN)
Brand Name: Floxin

Floxin is used for:

Treating mild to moderate infections caused by certain bacteria.

Floxin is a fluoroquinolone antibiotic. It kills sensitive bacteria by stopping the production of essential proteins needed by the bacteria to survive.

Do NOT use Floxin if:

  • you are allergic to any ingredient in Floxin
  • you are allergic to any other fluoroquinolone antibiotic (eg, ciprofloxacin)
  • you are taking nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen) or typhoid oral vaccine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Floxin :

Some medical conditions may interact with Floxin . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have diabetes
  • if you have heart problems, including irregular heartbeat; liver or kidney disease; or low potassium levels
  • if you have Alzheimer disease, hardening in the arteries in the brain, seizures, increased pressure on the brain, or another central nervous system disorder
  • if you have tendonitis
  • if your skin is sensitive to sunlight

Some MEDICINES MAY INTERACT with Floxin . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Foscarnet, NSAIDs (eg, ibuprofen), or tramadol because the risk of seizures may be increased
  • Insulin or other medicines for diabetes (eg, glipizide) because the risk of low blood sugar may be increased
  • Anticoagulants (eg, warfarin), procainamide, or theophylline because the risk of their side effects may be increased by Floxin
  • Live typhoid vaccine because its effectiveness may be decreased by Floxin
  • Aluminum salts (eg, aluminum hydroxide), iron salts (oral) (eg, ferrous sulfate), or magnesium salts (eg, magnesium hydroxide) because they may decrease Floxin 's effectiveness. Take ofloxacin 2 hours before or 2 hours after these medicines to offset this effect.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Floxin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Floxin :

Use Floxin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Floxin by mouth with or without food.
  • Take Floxin with a full glass of water (8 oz/240 mL). Drink several glasses of water daily, unless otherwise instructed by your doctor.
  • Do not drink milk or eat dairy products, or take antacids, sucralfate, or vitamins within 2 hours before or after taking Floxin .
  • Floxin works best if it is taken at the same time each day.
  • To clear up your infection completely, take Floxin for the full course of treatment. Keep taking it even if you feel better in a few days.
  • If you miss a dose, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Floxin .

Important safety information:

  • Floxin may cause dizziness, drowsiness, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Floxin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Floxin may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Floxin . Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Diabetes patients - Floxin may affect your blood sugar when taken along with insulin or other medicines for diabetes. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Tell your doctor or dentist that you take Floxin before you receive any medical or dental care, emergency care, or surgery.
  • Long-term or repeated use of Floxin may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • If you experience pain or inflammation, or rupture a tendon during or shortly after taking ofloxacin, contact your health care provider immediately.
  • Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
  • Be sure to use Floxin for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Lab tests, including kidney function tests, may be performed while you use Floxin . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Floxin should not be used in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Floxin while you are pregnant. Floxin is found in breast milk. Do not breast-feed while taking Floxin .

Possible side effects of Floxin :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; headache; loss of appetite; nausea; nervousness; sensitivity to sunlight; trouble sleeping; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation; anxiety; bizarre behavior; bloody stools; confusion; convulsions; dark urine; depression; diarrhea (severe or continuing); difficulty swallowing; excessive urination, thirst, or hunger; fatigue; fever; hallucinations; hoarseness; increased pressure within the head; joint or muscle pain or swelling; lightheadedness; loss of consciousness; nervousness; nightmares; pale stools; paranoia; rapid heartbeat; rash, skin burning, redness, swelling, blisters, itching, or skin inflammation; restlessness; seizures; shock (pale skin); sleeplessness; stomach pain/cramps; suicidal thoughts; tendon pain, inflammation, or swelling; tightness of the throat; tingling; tremors; urination problems; vaginal irritation or discharge; yellowing of skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include: facial swelling and numbness; hot and cold flushes; mild to moderate disorientation; slurring of speech.

Proper storage of Floxin :

Store Floxin below 86 degrees F (30 degrees C). Store away from heat, moisture, and light. Store in a tightly closed container. Do not store in the bathroom. Keep Floxin out of the reach of children and away from pets.

General information:

  • If you have any questions about Floxin , please talk with your doctor, pharmacist, or other health care provider.
  • Floxin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is summary only. It does not contain all information about Floxin . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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