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All about: Fluticasone propionate

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Generic name: Fluticasone propionate
Brand names: Cutivate

Why is Fluticasone propionate prescribed?

Cutivate cream and ointment are prescribed for relief of inflamed, itchy rashes and other inflammatory skin conditions.

Most important fact about Fluticasone propionate

When you use Cutivate, you inevitably absorb some of the medication through your skin and into the bloodstream. Too much absorption can lead to unwanted side effects elsewhere in the body. To keep this problem to a minimum, avoid using large amounts of Cutivate over large areas, and do not cover it with airtight dressings such as plastic wrap or adhesive bandages unless specifically told to do so by your doctor.

How should you use Fluticasone propionate?

Cutivate is for use only on the skin. Be careful to keep it out of your eyes.

--If you miss a dose...

Apply it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to your regular schedule.

--Storage instructions...

Store at room temperature.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Cutivate.

  • Side effects of Cutivate may include:
    Burning, dryness, infected or worsening eczema, itchy spots, rash, skin irritation, stinging

Side effects occur more frequently with the use of airtight bandages. In children, the more likely side effects may include a burning sensation, hives, inflammation, rash, and red blotches on the face and body.

Why should Fluticasone propionate not be prescribed?

If you are sensitive to or have ever had an allergic reaction to fluticasone propionate or other steroid medications, you should not use Cutivate. Make sure your doctor is aware of any drug reactions you have experienced.

Special warnings about Fluticasone propionate

Do not use Fluticasone propionate for any disorder other than the one for which it was prescribed.

Do not use Cutivate cream on the face, underarms, or groin areas unless your doctor tells you to do so. Do not apply Cutivate if you have an infection in the affected skin area. Tell your doctor if you have had any other problems in that area.

The treated skin area should not be bandaged, covered, or wrapped unless you have been directed to do so by your doctor.

Do not apply Cutivate cream to the diaper area because covering a treated area with waterproof diapers or plastic pants can increase unwanted absorption of Cutivate.

Do not use Cutivate to treat rosacea or skin inflammation near the mouth. Also avoid using Cutivate on thin, weakened skin that has lost its elasticity.

If an irritation or allergic reaction develops while using Cutivate, notify your doctor.

The drug can interfere with the thyroid, pituitary, and adrenal glands, causing a problem called Cushing's syndrome (weight gain, reddening of the face and neck, growth of excess facial hair, high blood pressure, and mental disturbances), hyperglycemia (excess glucose in the blood), and glucosuria (urinary excretion of glucose). Your doctor should monitor your condition and periodically check your glandular function if you are applying a large dose of any potent steroid preparation to a large area of your skin.

Steroid medications such as Cutivate are more likely to cause side effects in children. Problems can include Cushing's syndrome and other adrenal problems, stunted growth, and high pressure inside the head. This excess pressure can lead to bulges in the skull, headaches, and eventually loss of vision.

Possible food and drug interactions when taking Fluticasone propionate

No interactions with food or other drugs have been reported.

Special information if you are pregnant or breastfeeding

The effects of Cutivate during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. It is not known whether Fluticasone propionate appears in breast milk. If Fluticasone propionate is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment is finished.

Recommended dosage

ADULTS

Apply a thin film of Cutivate cream or ointment to the affected skin areas 1 or 2 times a day. Rub in gently. Contact your doctor if there is no improvement within 2 weeks.

Cutivate should not be used with tight, occlusive dressings or bandages.

CHILDREN

Cutivate cream may be used with caution to treat children over 3 months of age. Apply a thin film of Cutivate cream to the affected skin areas 1 or 2 times a day. Rub in gently. The safety of Cutivate cream to treat children for longer than 4 weeks has not been established.

Cutivate ointment is not recommended for use in children.

Cutivate should not be used with tight, occlusive dressings or bandages.

The safety and effectiveness of Cutivate cream have not been established for treatments lasting more than 4 weeks in children or for infants below age 3 months.

Cutivate ointment is not recommended for use in children.

Overdosage

With extensive or long-term use of Cutivate, hormone absorbed into the bloodstream may cause a group of symptoms called Cushing's syndrome.

  • Symptoms of Cushing's syndrome may include:
    Acne, depression, excessive hair growth, high blood pressure, humped upper back, insomnia, moonfaced appearance, obese trunk, paranoia, stretch marks, wasted limbs, stunted growth (in children), susceptibility to bruising, fractures, and infections

Cushing's syndrome may also trigger diabetes mellitus.

If it is left uncorrected, Cushing's syndrome may become serious. If you suspect your long-term use of Cutivate has led to this problem, seek medical attention immediately.

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