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All about: Fosphenytoin

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Generic Name: Fosphenytoin (FOS-fen-ih-toe-in)
Brand Name: Cerebyx

Fosphenytoin is used for:

Treating certain types of seizures and preventing and treating seizures during surgery of the nervous system. It may also be used for other conditions as determined by your doctor.

Fosphenytoin is an anticonvulsant. It works by slowing abnormal nerve impulses in the brain that cause seizures.

Do NOT use Fosphenytoin if:

  • you are allergic to any ingredient in Fosphenytoin
  • you have an abnormally slow heartbeat or a certain type of irregular heartbeat (eg, heart block, Adams-Stokes syndrome)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Fosphenytoin :

Some medical conditions may interact with Fosphenytoin . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have the blood disease porphyria, low blood pressure with heart failure, lymph node problems (eg, pain, swelling, lymphoma), liver or kidney problems, or if you use alcohol

Many prescription and nonprescription medicines (eg, used for infections, inflammation, aches and pains, high blood pressure, high cholesterol, seizures), multivitamin products, and herbal or dietary supplements (eg, herbal teas, coenzyme Q10, garlic, ginseng, ginkgo, St. John's wort) may interact with Fosphenytoin . Be sure your doctor knows all medications you are taking. Ask your health care provider about whether any of your medicines may interact with Fosphenytoin .

This may not be a complete list of all interactions that may occur. Ask your health care provider if Fosphenytoin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Fosphenytoin :

Use Fosphenytoin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Fosphenytoin is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Fosphenytoin at home, a health care provider will teach you how to use it. Be sure you understand how to use Fosphenytoin . Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do not use Fosphenytoin if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of Fosphenytoin , use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Fosphenytoin .

Important safety information:

  • Fosphenytoin may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Fosphenytoin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Tell your doctor or dentist that you take Fosphenytoin before you receive any medical or dental care, emergency care, or surgery.
  • Proper dental care is important while you are taking Fosphenytoin . Brush and floss your teeth and visit the dentist regularly.
  • Do not drink alcohol while you are using Fosphenytoin without checking with your health care provider.
  • Diabetes patients - Fosphenytoin may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • LAB TESTS, including phenytoin serum levels, may be performed while you use Fosphenytoin . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Hormonal birth control (eg, birth control pills) may not work as well while you are using Fosphenytoin . To prevent pregnancy, use an extra form of birth control (eg, condoms).
  • PREGNANCY and BREAST-FEEDING: This medicine has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Fosphenytoin while you are pregnant. Fosphenytoin is found in breast milk. Do not breast-feed while taking Fosphenytoin .

Possible side effects of Fosphenytoin :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Confusion; dizziness; drowsiness; nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abnormal muscle movements; back and forth eye movements; blurred or double vision; chest pain; clumsiness or unsteadiness; fever or sore throat; irregular heartbeat; joint pain; pain, swelling, or tenderness of the lymph nodes; rash; severe burning, itching, or numbness of the skin; severe stomach pain; shaky movements; slurred speech; staggering walk; swollen or tender gums; unusual bruising or bleeding; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include confusion; dizziness; drowsiness; loss of consciousness; nausea; slurred speech; tremor; unsteadiness; unusual eye movements.

Proper storage of Fosphenytoin :

Fosphenytoin is usually handled and stored by a health care provider. If you are using Fosphenytoin at home, store Fosphenytoin as directed by your pharmacist or health care provider.

General information:

  • If you have any questions about Fosphenytoin , please talk with your doctor, pharmacist, or other health care provider.
  • Fosphenytoin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Fosphenytoin . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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