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All about: haemophilus b conjugate (PRP-T) vaccine

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Generic Name: haemophilus b conjugate (PRP-T) vaccine (hem OFF il us B KON ju gate)
Brand Names: ActHIB

What is haemophilus B conjugate (PRP-T) vaccine?

Haemophilus B is a type of influenza (flu) caused by bacteria.

Haemophilus B bacteria can infect the lungs or throat, and can also spread to the blood, bones, joints, brain, or spinal cord. It can cause breathing problems or meningitis, and these infections can be fatal.

Haemophilus B disease can spread from one person to another through small droplets of saliva that are expelled into the air when an infected person coughs or sneezes. The bacteria can also be passed through contact with objects the infected person has touched, such as a door handle, or other surface. The bacteria can also be passed through kissing, or sharing a drinking glass or eating utensil with an infected person.

Haemophilus B conjugate vaccine is used to prevent infection caused by haemophilus B bacteria, and is sometimes combined with vaccines to protect against other diseases. Haemophilus B vaccine will not protect against other types of influenza.

Haemophilus B conjugate vaccine works by exposing your child to a small dose of the bacteria or a protein from the bacteria, which causes the body to develop immunity to the disease. This vaccine will not treat an active infection that has already developed in the body.

Haemophilus B conjugate vaccine is for use in children between the ages of 2 months and 18 months old.

Like any vaccine, haemophilus B conjugate vaccine may not provide protection from disease in every person.

What is the most important information I should know about this vaccine?

The haemophilus B conjugate vaccine is given in a series of shots. In most cases, this vaccine is given as 2 separate shots, 2 months apart. A booster dose is then given 2 months after the last shot, or no later than 18 months of age.

Your child's individual booster schedule may be different from these guidelines. Follow your doctor's instructions or the schedule recommended by the health department of the state you live in.

Be sure your child receives all recommended doses of this vaccine. If your child does not receive the full series of vaccines, he or she may not be fully protected against the disease.

Your child can still receive a vaccine if he or she has a cold or fever. In the case of a more severe illness with a fever or any type of infection, wait until the child gets better before receiving this vaccine.

Your child should not receive a booster vaccine if he or she had a life-threatening allergic reaction after the first shot.

Keep track of any and all side effects your child has after receiving this vaccine. When the child receives a booster dose, you will need to tell the doctor if the previous shots caused any side effects.

Becoming infected with haemophilus B is much more dangerous to your child's health than receiving the vaccine to protect against it. Like any medicine, this vaccine can cause side effects, but the risk of serious side effects is extremely low.

What should I discuss with my healthcare provider before receiving this vaccine?

Your child should not receive this vaccine if he or she has ever had an allergic reaction to a haemophilus B or a tetanus vaccine, or if the child has received cancer chemotherapy or radiation treatment in the past 3 months.

Before receiving haemophilus B conjugate vaccine, tell your child's doctor if the child is allergic to any drugs, or has:

  • a bleeding or blood clotting disorder such as hemophilia or easy bruising;

  • a history of seizures;

  • a neurologic disorder or disease affecting the brain (or if this was a reaction to a previous vaccine);

  • an allergy to latex rubber;

  • a weak immune system caused by disease, bone marrow transplant, or by using certain medicines or receiving cancer treatments; or

  • if the child is taking a blood thinner such as warfarin (Coumadin).

FDA pregnancy category C. This vaccine may be harmful to an unborn baby and should not be given to a pregnant woman. Haemophilus B conjugate vaccine should not be given to a woman who is breast-feeding a baby.

How is this vaccine given?

This vaccine is given as an injection (shot) into a muscle. Your child will receive this injection in a doctor's office or other clinic setting.

Haemophilus B conjugate vaccine is given to children between the ages of 2 months and 18 months old. It may also be given to an older child with a medical conditions such as HIV or AIDS, sickle cell disease, or who is receiving cancer treatments or a bone marrow transfusion.

The haemophilus B conjugate vaccine is given in a series of shots. In most cases, this vaccine is given as 2 separate shots, 2 months apart. A booster dose is then given 2 months after the last shot, or no later than 18 months of age.

Your child's individual booster schedule may be different from these guidelines. Follow your doctor's instructions or the schedule recommended by the health department of the state you live in.

Your child can still receive a vaccine if he or she has a cold or fever. In the case of a more severe illness with a fever or any type of infection, wait until the child gets better before receiving this vaccine.

Your doctor may recommend treating fever and pain with an aspirin-free pain reliever such as acetaminophen (Tylenol) or ibuprofen (Motrin, Advil, and others) when the shot is given and for the next 24 hours. Follow the label directions or your doctor's instructions about how much of this medicine to give your child.

It is especially important to prevent fever from occurring in a child who has a seizure disorder such as epilepsy.

What happens if I miss a dose?

Contact your doctor if you will miss a booster dose or if you get behind schedule. The next dose should be given as soon as possible. There is no need to start over.

Be sure your child receives all recommended doses of this vaccine. If your child does not receive the full series of vaccines, he or she may not be fully protected against the disease.

What happens if I overdose?

An overdose of this vaccine is not likely to occur.

What should I avoid before or after receiving this vaccine?

There are no restrictions on food, beverages, or activity before or after receiving this vaccine unless your child's doctor has told you otherwise.

This vaccine side effects

Keep track of any and all side effects your child has after receiving this vaccine. When the child receives another haemophilus B vaccine in the future, you will need to tell the child's doctor if the first shot caused any side effects.

Becoming infected with haemophilus B is much more dangerous to your child's health than receiving the vaccine to protect against it. Like any medicine, this vaccine can cause side effects, but the risk of serious side effects is extremely low.

Get emergency medical help if your child has any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if your child has any of these serious side effects:
  • extreme drowsiness, fainting;

  • fussiness, irritability, crying for an hour or longer;

  • seizure (black-out or convulsions); or

  • high fever (within a few hours or a few days after the vaccine).

Less serious side effects may include:

  • redness, pain, swelling, or a lump where the shot was given;

  • low fever;

  • mild fussiness or crying;

  • joint pain, body aches;

  • drowsiness; or

  • diarrhea.

Side effects other than those listed here may also occur. Contact your doctor about any side effect that seems unusual or that is especially bothersome to the child.

What other drugs will affect haemophilus B conjugate (PRP-T) vaccine?

Before receiving this vaccine, tell the doctor about all other vaccines your child has recently received.

Also tell the doctor if your child has recently received drugs or treatments that can weaken the immune system, including:

  • an oral, nasal, inhaled, or injectable steroid medicine;

  • medications to treat psoriasis, rheumatoid arthritis, or other autoimmune disorders, such as azathioprine (Imuran), efalizumab (Raptiva), etanercept (Enbrel), leflunomide (Arava), and others; or

  • medicines to treat or prevent organ transplant rejection, such as basiliximab (Simulect), cyclosporine (Sandimmune, Neoral, Gengraf), muromonab-CD3 (Orthoclone), mycophenolate mofetil (CellCept), sirolimus (Rapamune), or tacrolimus (Prograf).

If your child is using any of these medications, he or she may not be able to receive haemophilus B conjugate vaccine, or may need to wait until the other treatments are finished.

There may be other drugs not listed that can affect haemophilus B conjugate vaccine. Tell your doctor about all the prescription and over-the-counter medications your child uses. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your child's doctor.

Where can I get more information?

  • Your doctor or pharmacist may have information about haemophilus B conjugate vaccine written for health professionals that you may read. You may also find additional information from your local health department or the Centers for Disease Control and Prevention.

  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 1.03. Revision Date: 07/13/2007 8:33:03 AM.

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