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All about: Hespan

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Generic Name: Hetastarch in Sodium Chloride Injection (HET-uh-starch)
Brand Name: Hespan

Hespan is used for:

Increasing plasma volume during shock caused by bleeding, burns, surgery, or other trauma. It is not a substitute for blood or plasma. It may also be used for other conditions as determined by your doctor.

Hespan is a synthetic plasma expander. It works by producing expansion of plasma blood volume.

Do NOT use Hespan if:

  • you are allergic to any ingredient in Hespan or to hydroxyethyl starch
  • you have bleeding disorders or conditions in which volume overload may occur (eg, heart failure; kidney disease with urination problems [eg, inability, infrequency] not related to hypovolemia)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Hespan :

Some medical conditions may interact with Hespan . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances (especially to corn)
  • if you have heart disease, kidney problems, or a history of liver disease
  • if you have high blood sodium levels or blood volume levels
  • if you have risk factors for congestive heart failure or fluid in the lungs

Some MEDICINES MAY INTERACT with Hespan . However, no specific interactions with Hespan are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Hespan may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Hespan :

Use Hespan as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Hespan is usually administered as an injection at your doctor's office, hospital, or clinic. If you are using Hespan at home, carefully follow the injection procedures taught to you by your health care provider.
  • If Hespan contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.
  • When smaller doses are required, the unused portion should be discarded.
  • Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.
  • If you miss a dose of Hespan , use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Hespan .

Important safety information:

  • Hespan may reduce the number of clot-forming cells (platelets) in your blood. To prevent bleeding, avoid situations in which bruising or injury may occur. Report any unusual bleeding, bruising, blood in stools, or dark, tarry stools to your doctor.
  • Additional monitoring of your dose or condition may be needed if you are taking anticoagulants (eg, warfarin), corticosteroids (eg, prednisone), or corticotropin.
  • LAB TESTS, including complete blood cell counts, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Hespan with extreme caution in CHILDREN. Safety and effectiveness have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Hespan , discuss with your doctor the benefits and risks of using Hespan during pregnancy. It is unknown if Hespan is excreted in breast milk. If you are or will be breast-feeding while you are using Hespan , check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Hespan :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Coughing; flu-like symptoms (chills, headache, mild fever); flushing; lightheadedness; muscle pains; restlessness; sneezing; swelling of ankles or feet; swollen glands in the jaw area; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fast or irregular heartbeat; unusual bleeding or bruising.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Hespan :

Hespan is usually handled and stored by a health care provider. If you are using Hespan at home, store Hespan as directed by your pharmacist or health care provider. Keep Hespan out of the reach of children and away from pets.

General information:

  • If you have any questions about Hespan , please talk with your doctor, pharmacist, or other health care provider.
  • Hespan is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Hespan . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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