24 . September , 2018 - Monday
Check todays hot topics or new products

Find a Drug: Advanced

Please Sign in or Register

All about: Hiprex

Big Image

Generic Name: methenamine (meh THEH na meen)
Brand Names: Hiprex, Mandelamine, Urex

What is Hiprex (methenamine)?

Methenamine is a urinary antiinfective medicine. Methenamine fights bacteria in the urine and bladder.

Methenamine may be used to treat and prevent urinary tract infections.

Methenamine may also be used for purposes other than those listed here.

What is the most important information I should know about Hiprex (methenamine)?

Take all of the methenamine that has been prescribed for you even if you begin to feel better. Symptoms may start to improve before the infection is completely treated. Take each dose with a full glass of water. Plenty of fluid should be consumed while taking methenamine.

Your healthcare provider may recommend drinking additional water and/or certain fruit juices (e.g., cranberry, plum, prune) and increased protein in the diet while taking methenamine to ensure adequate hydration and acidity of the urine. It may also be recommended to avoid citrus fruits and juices (e.g., orange, grapefruit, lemon), milk and dairy products, and antacids during treatment with methenamine. These products may decrease the effectiveness of methenamine. Follow your healthcare provider's instructions.

What should I discuss with my healthcare provider before taking Hiprex (methenamine)?

Before taking methenamine, talk to your doctor if you

  • have liver problems;
  • have kidney problems;
  • have other medical conditions; or

  • take other medications.

You may not be able to take methenamine, or you may require a dosage adjustment or special monitoring during treatment.

Methenamine is in the FDA pregnancy category C. This means that it is not known whether it will be harmful to an unborn baby. Do not take methenamine without first talking to your doctor if you are pregnant or could become pregnant during treatment. Methenamine passes into breast milk and may affect a nursing baby. Do not take methenamine without first talking to your doctor if you are breast-feeding a baby.

How should I take Hiprex (methenamine)?

Take methenamine exactly as directed by your doctor. If you do not understand these instructions, ask your doctor, nurse, or pharmacist to explain them to you.

Take each dose with a full glass of water. Plenty of fluid should be consumed while taking methenamine. Methenamine should be taken with food to reduce stomach upset. Do not crush or chew the enteric-coated tablets. Swallow them whole. They are specially formulated to be less irritating to the stomach. Talk to your doctor if swallowing the tablets is difficult. Shake the liquid form of methenamine well before measuring a dose. To ensure that you get the correct dose, measure the suspension with a dose-measuring spoon, dropper, or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

It is important to take methenamine at regularly scheduled intervals to get the most benefit.

Take all of the methenamine that has been prescribed for you even if you begin to feel better. Symptoms may start to improve before the infection is completely treated.

Your healthcare provider may recommend drinking additional water and/or certain fruit juices (e.g., cranberry, plum, prune) and increased protein in the diet while taking methenamine to ensure adequate hydration and acidity of the urine. It may also be recommended to avoid citrus fruits and juices (e.g., orange, grapefruit, lemon), milk and dairy products, and antacids during treatment with methenamine. These products may decrease the effectiveness of methenamine. Follow your healthcare provider's instructions.

Store methenamine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the dose you missed and take only the next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

What happens if I overdose?

Seek emergency medical attention if an overdose is suspected.

Symptoms of a methenamine overdose are not known.

What should I avoid while taking Hiprex (methenamine)?

Your healthcare provider may recommend drinking additional water and/or certain fruit juices (e.g., cranberry, plum, prune) and increased protein in the diet while taking methenamine to ensure adequate hydration and acidity of the urine. It may also be recommended to avoid citrus fruits and juices (e.g., orange, grapefruit, lemon), milk and dairy products, and antacids during treatment with methenamine. These products may decrease the effectiveness of methenamine. Follow your healthcare provider's instructions.

Hiprex (methenamine) side effects

If you experience any of the following serious side effects, stop taking methenamine and seek emergency medical attention or contact your doctor immediately:
  • an allergic reaction (shortness of breath; closing of the throat; swelling of the lips, face, or tongue; or hives;

  • lower back or side pain;

  • blood in urine; or

  • increasingly painful or difficult urination.

Other, less serious side effects may be more likely to occur. Continue to take methenamine and talk to your doctor if you experience

  • nausea or upset stomach;

  • decreased appetite; or

  • skin rash.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Hiprex (methenamine)?

Do not take methenamine without first talking to your doctor if you are taking:
  • a carbonic anhydrase inhibitor such as acetazolamide (Diamox), dichlorphenamide (Daranide), or methazolamide (Glauctabs, MZM, Neptazane);

  • a sulfa product such as sulfadiazine, sulfamethoxazole (Bactrim, Septra, others), sulfasalazine (Azulfidine), and others;

  • a diuretic (water pill); or

  • a product that contains aluminum, calcium, magnesium, sodium bicarbonate, potassium or sodium citrate, or citric acid (such as antacids, vitamin or mineral pills, urinary alkalinizers, and other medications).

You may not be able to take methenamine, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with methenamine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

  • Your pharmacist has additional information about methenamine written for health professionals that you may read.

What does my medication look like?

Methenamine is available with a prescription under the brand names Hiprex, Urex, and Mandelamine. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 1.02. Revision Date: 2/13/04 3:58:18 PM.

Recent Drug Updates at DrugIndexOnline:





Acamprosate calcium Acamprosate calcium
Generic name: Acamprosate calcium Brand names: Campral Why is Acamprosate calcium prescribed? Campral is prescribed to treat alcohol dependence. It helps people who have already stopped drinking alcohol keep from starting again. You must be alcohol-free before taking Campral for it to work. You more...

Guaiphen-PD Guaiphen-PD
Generic Name: guaifenesin and phenylephrine (gwye FEH ne sin and feh nill EFF rin) Brand Names: Amidal, Amitex LA, Chemdal, Crantex, Crantex ER, Crantex LA Capsules, Crantex LA Tablets, Deconex, Deconsal II, Deconsal Pediatric, Despec, Duraphen II, Efasin, Endal, Entex, Entex ER, Entex LA more...

Intron-A Solution Intron-A Solution
Generic Name: Interferon Alfa-2b Injection Solution (in-ter-FEER-on AL-fuh) Brand Name: Intron-AIntron-A Solution can cause or worsen some serious medical conditions, including psychiatric conditions (eg, depression), immune system problems (autoimmune conditions such as lupus or rheumatoid arth more...

Nexavar Nexavar
Generic Name: Sorafenib (sor-ah-FEN-ib) Brand Name: NexavarNexavar is used for:Treating advanced kidney cancer. Nexavar is a multikinase inhibitor. It works by decreasing tumor growth and replication. Do NOT use Nexavar if:you are allergic to any ingredient in Nexavar Contact your doctor or more...

Nimodipine Nimodipine
Generic Name: Nimodipine Capsules (nye-MOE-di-peen) Brand Name: NimotopNimodipine should only be taken by mouth. Life-threatening and sometimes fatal side effects may occur if Nimodipine is administered by injection. Nimodipine is used for:Reducing problems due to lack of oxygen caused by ble more...

Octreotide Octreotide
Some commonly used brand names are: In the U.S.— Sandostatin Sandostatin LAR Depot In Canada— Sandostatin Category Antidiarrheal, acquired immunodeficiency syndrome (AIDS) antidiarrheal, gastrointestinal tumor antihemorrhagic, bleeding gastroesophageal varices antihypoglycemi more...

Palladone Palladone
Note: Palladone (hydromorphone hydrochloride extended release capsules) was suspended from the U.S. market in July 2005 by the manufacturer. Serious side effects were reported when Palladone was taken with alcohol. Some commonly used brand names are: In the U.S.— Astramorph PF 10 more...

Pedialyte Freezer-Pops Pedialyte Freezer-Pops
Generic Name: Electrolyte Freezer-Pops (e-LECK-troe-lite) Brand Name: Examples include Pedialyte Freezer Pops and ReVital Freezer PopsPedialyte Freezer-Pops is used for:Treating or preventing dehydration caused by vomiting or diarrhea. It may also be used for other conditions as determined by y more...