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All about: Hydrocortisone/Neomycin/Polymyxin B Suspension

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Generic Name: Hydrocortisone/Neomycin/Polymyxin B Ear Suspension (HYE-droe-KOR-ti-sone/NEE-oh-MYE-sin/POL-ee-MIX-in)
Brand Name: Examples include Cortisporin and Cortomycin

Hydrocortisone/Neomycin/Polymyxin B Suspension is used for:

Treating infections of the ear caused by certain bacteria. It may also be used for other conditions as determined by your doctor.

Hydrocortisone/Neomycin/Polymyxin B Suspension is a combination of 2 antibiotics and a corticosteroid. The antibiotics work by slowing the growth of, or killing, sensitive bacteria. The corticosteroid reduces inflammation.

Do NOT use Hydrocortisone/Neomycin/Polymyxin B Suspension if:

  • you are allergic to any ingredient in Hydrocortisone/Neomycin/Polymyxin B Suspension, to other aminoglycosides (eg, gentamicin), or to other corticosteroids (eg, prednisone)
  • you have a viral infection of the ear (eg, herpes simplex, chickenpox, shingles)
  • you have a perforated ear drum

Contact your doctor or health care provider right away if any of these apply to you.

Before using Hydrocortisone/Neomycin/Polymyxin B Suspension:

Some medical conditions may interact with Hydrocortisone/Neomycin/Polymyxin B Suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have asthma

Some MEDICINES MAY INTERACT with Hydrocortisone/Neomycin/Polymyxin B Suspension. Because little, if any, of Hydrocortisone/Neomycin/Polymyxin B Suspension is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Hydrocortisone/Neomycin/Polymyxin B Suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Hydrocortisone/Neomycin/Polymyxin B Suspension:

Use Hydrocortisone/Neomycin/Polymyxin B Suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Hydrocortisone/Neomycin/Polymyxin B Suspension is only for the ear. Do not get it in your eyes, nose, or mouth. If you get Hydrocortisone/Neomycin/Polymyxin B Suspension in your eyes, rinse immediately with cool tap water.
  • Wash your hands before and after using Hydrocortisone/Neomycin/Polymyxin B Suspension.
  • Wash and dry the outer ear with a sterile cotton applicator.
  • Shake well before each use.
  • Lie down or tilt your head so that the affected ear faces up. For adults, gently pull the earlobe up and back to straighten the ear canal. For children, gently pull the earlobe down and back to straighten the ear canal. Drop the medicine into the ear canal. Keep the ear facing up for several minutes so the medicine can run to the bottom of the ear canal. A clean cotton plug may be gently inserted into the ear canal to prevent medicine from leaking out. To prevent germs from getting into your medicine, do not touch the applicator to any surface, including the ear. Keep the container tightly closed.
  • To clear up your infection completely, use Hydrocortisone/Neomycin/Polymyxin B Suspension for the full course of treatment. Keep using it even if you feel better in a few days.
  • If you miss a dose of Hydrocortisone/Neomycin/Polymyxin B Suspension, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Hydrocortisone/Neomycin/Polymyxin B Suspension.

Important safety information:

  • Hydrocortisone/Neomycin/Polymyxin B Suspension only works against bacteria; it does not treat fungal or viral infections.
  • Be sure to use Hydrocortisone/Neomycin/Polymyxin B Suspension for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Long-term or repeated use of Hydrocortisone/Neomycin/Polymyxin B Suspension may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • If your symptoms do not get better within 7 days or if they get worse, check with your doctor.
  • Do NOT take more than the recommended dose or use for longer than 7 days without checking with your doctor.
  • Do not use Hydrocortisone/Neomycin/Polymyxin B Suspension for other ear conditions at a later time.
  • Some of these products contain sulfites. Sulfites may cause an allergic reaction in some patients (eg, asthma patients). If you have ever had an allergic reaction to sulfites, ask your pharmacist if your product has sulfites in it.
  • Tell your doctor or dentist that you take Hydrocortisone/Neomycin/Polymyxin B Suspension before you receive any medical or dental care, emergency care, or surgery.
  • Hydrocortisone/Neomycin/Polymyxin B Suspension should be used with extreme caution in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Hydrocortisone/Neomycin/Polymyxin B Suspension while you are pregnant. It is not known if Hydrocortisone/Neomycin/Polymyxin B Suspension is found in breast milk after topical use. If you are or will be breast-feeding while you use Hydrocortisone/Neomycin/Polymyxin B Suspension, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Hydrocortisone/Neomycin/Polymyxin B Suspension:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Mild, temporary burning or stinging.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); acne-like rash; changes in hearing; decreased urination; dry, scaly, or peeling skin at the application site; continued burning or stinging; excessive hair growth; inflamed hair follicles; inflammation around the mouth; loss of hearing; muscle weakness; pain, redness, itching, irritation, or swelling not present when you began using Hydrocortisone/Neomycin/Polymyxin B Suspension; thinning, softening, or discoloration of the skin; unusual weight gain, especially in the face.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center ( http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Hydrocortisone/Neomycin/Polymyxin B Suspension:

Store Hydrocortisone/Neomycin/Polymyxin B Suspension between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Keep the container tightly closed. Keep Hydrocortisone/Neomycin/Polymyxin B Suspension out of the reach of children and away from pets.

General information:

  • If you have any questions about Hydrocortisone/Neomycin/Polymyxin B Suspension, please talk with your doctor, pharmacist, or other health care provider.
  • Hydrocortisone/Neomycin/Polymyxin B Suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Hydrocortisone/Neomycin/Polymyxin B Suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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