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All about: Intal

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Generic name:
Brand names: Intal, Nasalcrom

Why is Intal prescribed?

Intal contains the antiasthmatic/antiallergic medication cromolyn sodium.

Different forms of the drug are used to manage bronchial asthma, to prevent asthma attacks, and to prevent and treat seasonal and chronic allergies.

The drug works by preventing certain cells in the body from releasing substances that can cause allergic reactions or prompt too much bronchial activity. It also helps prevent bronchial constriction caused by exercise, aspirin, cold air, and certain environmental pollutants such as sulfur dioxide.

Most important fact about Intal

Intal does not help an acute asthma attack. When taken to prevent severe bronchial asthma, it can be 4 weeks before you feel its maximum benefit, though some people get relief sooner. Do not discontinue the inhalation capsules or nasal solution abruptly without the advice of your doctor.

How should you take Intal?

Intal capsules should not be swallowed. They are for inhalation using the Spinhaler turbo-inhaler. The contents of 1 capsule are usually inhaled 4 times daily at regular intervals. Wash the Spinhaler in warm water at least once a week; dry thoroughly. Replace the Spinhaler every 6 months.

Intal nebulizer solution should be inhaled using a power-operated nebulizer equipped with an appropriate face mask or mouthpiece. Hand-operated nebulizers are not suitable. It is important that the solution be inhaled at regular intervals, usually 4 times per day.

Intal aerosol spray can be used either for chronic asthma or to prevent an asthma attack. For chronic asthma, it must be inhaled at regular intervals, as directed by your doctor, usually 2 sprays inhaled 4 times daily. To prevent an asthma attack caused by exercise, cold air, or other irritants, the usual dose of 2 inhalation sprays should be taken between 10 and 60 minutes before exercising or exposure to cold or pollutants.

Nasalcrom nasal solution should be used with a metered nasal spray device, which should be replaced every 6 months. Blow your nose to clear your nasal passages before administering the spray. The nasal solution is used for nasal congestion due to seasonal or chronic allergies. For seasonal allergies, treatment is more effective if begun before the start of the allergy season. Treatment should then continue throughout the season. For year-round allergies, treatment may be required for up to 4 weeks before results are seen. Your doctor may find it necessary to add other allergy medications, such as antihistamines or decongestants, during initial treatment.

--If you miss a dose...

Take it as soon as you remember. Then take the rest of that day's doses at equally spaced intervals. Do not take 2 doses at once.

--Storage instructions...

Store at room temperature, away from light and heat. Keep the ampules in their foil pouch until you are ready to use them.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Intal.

  • More common side effects may include:
    Cough, nasal congestion or irritation, nausea, sneezing, throat irritation, wheezing

Why should Intal not be prescribed?

If you are sensitive to or have ever had an allergic reaction to cromolyn sodium or lactose, you should not take Intal. Make sure your doctor is aware of any drug reactions you have experienced.

Special warnings about Intal

Asthma symptoms may recur if the recommended dosage of Intal is reduced or discontinued. Intal has no role in the treatment of an acute asthmatic attack once it has begun. Obtain medical help immediately if you experience a severe attack.

If you have liver or kidney problems, your doctor may have to reduce the dosage or even take you off the drug altogether.

When using the capsules, you may accidentally inhale some powder, which can irritate your throat or make you cough. Try rinsing your mouth or taking a drink of water immediately before and/or after using the Spinhaler.

If your heartbeat is ever irregular or if you have any other kind of heart trouble, be sure your doctor knows about it before you use Intal aerosol spray.

Intal aerosol spray may not help you if your attack has been brought on by exercise.

Possible food and drug interactions when taking Intal

If you are taking other prescription or nonprescription drugs, discuss this with your doctor to determine if these drugs would interact with Intal.

Special information if you are pregnant or breastfeeding

The effects of Intal during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. It is not known whether Intal appears in breast milk. As with all medication, a nursing woman should use Intal only after careful consultation with her doctor.

Recommended dosage


Adults and Children 2 years Old and Over

For management of bronchial asthma, the usual dosage is 20 milligrams (1 capsule or ampule) inhaled 4 times daily at regular intervals, using the Spinhaler turbo-inhaler or power-operated nebulizer. If you have chronic asthma, Intal's effectiveness depends on your taking it regularly, as directed, and only after an attack has been controlled and you can inhale adequately.

For the prevention of an acute attack following exercise or exposure to cold, dry air or environmental irritants, the usual dose is 1 capsule or ampule inhaled shortly before exposure to the irritant. You may repeat the inhalation as needed for continued protection during prolonged exposure.


Adults and Children 5 Years Old and Over

For the management of bronchial asthma, the usual starting dose is 2 metered sprays taken at regular intervals, 4 times daily. This is the maximum dose that should be taken, and lower dosages may be effective in children. This drug should be used only after an asthma attack has been controlled and you can inhale adequately.

For the prevention of an acute asthma attack following exercise, exposure to cold air or environmental agents, the usual dose is inhalation of 2 metered sprays shortly (10 to 15 minutes but not more than 60 minutes) before exposure to the irritant.


Adults and Children 6 Years Old and Over

For the prevention and treatment of allergies caused by exposure to certain irritants, the usual dosage is 1 spray in each nostril 3 to 4 times per day at regular intervals, using the metered spray device. Your doctor may have you use the spray 6 times a day if you need it.


Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

  • Symptoms of Intal overdose may include:
    Difficulty breathing, heart failure, low blood pressure, slow heartbeat

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