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All about: isoxsuprine

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Generic Name: isoxsuprine (eye SOCK soo prin)
Brand Names: Vasodilan, Voxsuprine

What is isoxsuprine?

Isoxsuprine is in a class of drugs called vasodilators. Isoxsuprine relaxes veins and arteries, which makes them wider and allows blood to pass through them more easily.

These actions may help treat the symptoms of conditions such as cerebral vascular insufficiency (poor blood flow to the brain), arteriosclerosis (hardening of the arteries), Raynaud's phenomenon, and other conditions involving poor blood flow in the veins and arteries.

Isoxsuprine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about isoxsuprine?

Use caution when driving, operating machinery, or performing other hazardous activities. Isoxuprine may cause dizziness. If you experience dizziness, avoid these activities. Also, rise slowly from a sitting or lying position to avoid falling.

Notify your doctor if you experience a rash or bothersome irregular heartbeats.

Isoxsuprine has been withdrawn from the U.S. market.

What should I discuss with my healthcare provider before taking isoxsuprine?

Isoxsuprine should not be used immediately postpartum (after delivering a baby), or if you have a bleeding disorder. Talk to your doctor about any other medical conditions that you have.

Isoxsuprine is in the FDA pregnancy category C. This means that it is not known whether isoxsuprine will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether isoxsuprine passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take isoxsuprine?

Take isoxsuprine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. Isoxsuprine is usually taken three or four times a day. Follow your doctor's instructions.

It is important to take isoxsuprine regularly to get the most benefit.

Your doctor may want you to have blood tests or other medical evaluations during treatment with isoxsuprine to monitor progress and side effects.

Store isoxsuprine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention if an overdose is suspected.

Symptoms of an isoxsuprine overdose include weakness, lightheadedness, fainting, nausea, and vomiting.

What should I avoid while taking isoxsuprine?

Use caution when driving, operating machinery, or performing other hazardous activities. Isoxsuprine may cause dizziness. If you experience dizziness, avoid these activities. Also, rise slowly from a sitting or lying position to avoid falling.

Isoxsuprine side effects

Stop taking isoxsuprine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives).

Stop taking isoxsuprine and contact your doctor if you develop a rash.

Other, less serious side effects may be more likely to occur. Continue to take isoxsuprine and talk to your doctor if you experience

  • chest pain or an irregular heartbeat (call your doctor if this becomes bothersome);

  • nausea or vomiting; or

  • dizziness or weakness.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect isoxsuprine?

Drugs used to treat high blood pressure and other heart conditions may increase the effects of isoxsuprine. Special monitoring may be necessary.

Drugs other than those listed here may also interact with isoxsuprine or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

  • Your pharmacist has additional information about isoxsuprine written for health professionals that you may read.

What does my medication look like?

Isoxsuprine is available with a prescription and under the brand names Vasodilan and Voxsuprine in 10 mg and 20 mg capsules and in a generic tablet formulation. Other brand or generic formulations of this medication may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 2.05. Revision Date: 2/13/04 4:00:54 PM.

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