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All about: Ketoconazole Cream

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Generic Name: Ketoconazole Cream (kee-toe-KOE-na-zole)
Brand Name: Kuric and Nizoral

Ketoconazole Cream is used for:

Treating certain fungal infections of the skin.

Ketoconazole Cream is an imidazole antifungal. It works by killing sensitive fungi by interfering with the formation of the fungal cell membrane and weakening it. The weakened cell membrane allows the cell contents to leak out and results in the death of the fungus.

Do NOT use Ketoconazole Cream if:

  • you are allergic to any ingredient in Ketoconazole Cream

Contact your doctor or health care provider right away if any of these apply to you.

Before using Ketoconazole Cream:

Some medical conditions may interact with Ketoconazole Cream. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have low blood sugar levels, liver disease, or porphyria (a blood disease), sulfite sensitivity, or you drink more than 3 alcohol-containing drinks a day

Some MEDICINES MAY INTERACT with Ketoconazole Cream. Because little, if any, of Ketoconazole Cream is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Ketoconazole Cream may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Ketoconazole Cream:

Use Ketoconazole Cream as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Clean the affected area with soap and water and dry thoroughly. Apply enough medicine to cover the affected area. Rub in gently. Do not cover unless directed otherwise by your doctor. Wash your hands immediately after using Ketoconazole Cream, unless your hands are part of the treated area.
  • Keep Ketoconazole Cream out of your eyes, nose, and mouth. If this occurs, wash with water and contact your doctor, nurse, or pharmacist.
  • To clear up your infection completely, use Ketoconazole Cream for the full course of treatment. Keep using it even if you feel better in a few days.
  • If you miss a dose of Ketoconazole Cream, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Ketoconazole Cream.

Important safety information:

  • Be sure to use Ketoconazole Cream for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • If you use topical products too often, your condition may become worse.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Some of these products contain sulfites. Sulfites may cause an allergic reaction in some patients (eg, asthma patients). If you have ever had an allergic reaction to sulfites, ask your pharmacist if your product has sulfites in it.
  • Talk to your doctor before you take Ketoconazole Cream if you drink more than 3 drinks with alcohol per day.
  • Ketoconazole Cream should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Ketoconazole Cream while you are pregnant. It is not known if Ketoconazole Cream is found in breast milk. Do not breast-feed while using Ketoconazole Cream.

Possible side effects of Ketoconazole Cream:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Itching; mild irritation or stinging.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); reddening, blistering, peeling, itching, or burning of your skin.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Ketoconazole Cream:

Store Ketoconazole Cream between 59 and 77 degrees F (15 and 25 degrees C). Store in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Ketoconazole Cream out of the reach of children and away from pets.

General information:

  • If you have any questions about Ketoconazole Cream, please talk with your doctor, pharmacist, or other health care provider.
  • Ketoconazole Cream is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Ketoconazole Cream. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition
Copyright © 2007 Wolters Kluwer Health, Inc.

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