12 . November , 2018 - Monday
Check todays hot topics or new products

Find a Drug: Advanced

Please Sign in or Register

All about: Ketotifen Fumarate

Big Image Pronouncation: (KEY-toe-TIF-fen FEW-mah-rate)
Class: Ophthalmic antihistamine

Trade Names:
- Solution 0.025%

Mechanism of Action


Inhibits release of mediators from cells involved in hypersensitivity reactions.



Little systemic exposure following topical ocular administration.

Indications and Usage

Temporary prevention of itching of eyes caused by allergic conjunctivitis.


Standard considerations.

Dosage and Administration

Adults and children 3 yr of age and older

Ophthalmic 1 drop in affected eye(s) twice daily, every 8 to 12 h.

General Advice

  • For topical ophthalmic use only. Not for use on the skin, in the ear, or for injection into eye.
  • Ask patient to tilt head back and instill prescribed number of drops into affected eye(s) as ordered. Ask patient to close eye(s) for 2 to 3 min and apply light finger pressure to lacrimal sac for 1 to 2 min after installation. Do not touch top of dropper bottle to eye, fingers, or any other surface.
  • If using other topical ophthalmic medications, separate each medication by at least 5 min. Instill ophthalmic ointment last.


Store ophthalmic solution between 39° and 77°F. Keep tightly capped.

Drug Interactions

None well documented.

Laboratory Test Interactions

None well documented.

Adverse Reactions


Headache (10% to 25%).


Conjunctival injection, rhinitis (10% to 25%); ocular allergic reactions, burning or stinging of eye, conjunctivitis, eye discharge, dry eye, eye pain, eyelid disorder, itching eye, keratitis, lacrimation disorder, mydriasis, photophobia, rash, pharyngitis (less than 5%).


Flu syndrome (less than 5%).



Category C .




Safety and efficacy not established in children younger than 3 yr of age.

Patient Information

  • Remind patient that eye drops are for use in the eye only.
  • Teach patient proper technique for instilling eye drops: Wash hands; do not allow dropper to touch eye; tilt head back and look up; pull lower eyelid down; instill prescribed number of drops; close eye for 1 to 2 min and apply gentle pressure to bridge of nose for 1 to 3 min; do not rub eye.
  • Caution patient not to touch top of dropper bottle to eye, fingers, or any other surface.
  • Advise patient that if more than 1 topical ophthalmic medication is being used to separate each medication by at least 5 min apart. Instill ophthalmic ointment last.
  • Inform patient that eye redness, headaches, and runny nose are the most common side effects and to contact health care provider if they occur and are bothersome.
  • Advise patient to contact eye doctor if eye or eyelid inflammation is noted or if eye symptoms do not improve or worsen.
  • Instruct patient wearing contact lenses to remove lenses when instilling eye drops and, if wearing soft contact lenses, to wait 10 min after instilling drops before inserting lenses.
  • Caution patient wearing contact lenses not to wear lenses if eyes are red.

Recent Drug Updates at DrugIndexOnline:

Amoxicillin Suspension Amoxicillin Suspension
Generic Name: Amoxicillin Oral Suspension (a-MOX-ih-sil-in) Brand Name: Examples include Amoxil and TrimoxAmoxicillin Suspension is used for:Treating infections caused by certain bacteria. It may be used with other medications to treat ulcers of the small intestines. Amoxicillin Suspension is a more...

Entecavir Entecavir
Generic Name: Entecavir Tablets (en-TEK-a-vir) Brand Name: Baraclude Entecavir may increase the risk of severe and sometimes fatal lactic acidosis (buildup of lactic acid in the blood) or liver problems when used alone or with other medicines. Contact your doctor immediately if you experience m more...

Ergonovine Ergonovine
Generic Name: Ergonovine (er-goe-NOE-veen) Brand Name: Generic only. No brand available.Ergonovine is used for:Preventing and treating bleeding after delivery of a baby or an abortion. It may also be used for other conditions as determined by your doctor. Ergonovine is a uterine stimulant. It w more...

Flurandrenolide Cream Flurandrenolide Cream
Generic Name: Flurandrenolide Cream and Ointment (flure-an-DREN-oh-lide) Brand Name: Cordran SP and CordranFlurandrenolide Cream is used for:Treating inflammation and itching due to certain skin conditions. It may also be used for other conditions as determined by your doctor. Flurandrenolide C more...

Herbal Laxative Herbal Laxative
Some commonly used brand names are: In the U.S.— Agoral 35 Alophen 25 Alphamul 30 Alramucil Orange 7 Alramucil Regular 7 Bisac-Evac 25 Black-Draught 26 Black-Draught Lax-Senna 32 Carter's Little Pills 25 Cholac 14 Citroma 16 Citrucel Orange Flavor 3 Citrucel Sugar-Free Orange Flavor 3 Col more...

Ibuprofen Suspension Ibuprofen Suspension
Generic Name: Ibuprofen Suspension (Nonprescription) (EYE-bue-PROE-fen) Brand Name: Examples include Children's Advil and Children's Motrin Ibuprofen Suspension is a nonsteroidal anti-inflammatory drug (NSAID). It may cause an increased risk of serious and sometimes fatal heart and blood vessel more...

Mycelex Troche Mycelex Troche
Generic Name: clotrimazole (kloe TRIM a zole) Brand Names: Mycelex Troche What is Mycelex Troche (clotrimazole)? Clotrimazole is an antifungal medication. It is like an antibiotic but is used to treat yeast (fungal) infections. Oral clotrimazole is used to treat and prevent yeast infect more...

Phenytoin Injection Phenytoin Injection
Generic Name: Phenytoin Sodium Dosage Form: Injection Rx only IMPORTANT NOTE This drug must be administered slowly. In adults, do not exceed 50 mg per minute intravenously. In neonates, the drug should be administered at a rate not exceeding 1 mg/kg/min to 3 mg/kg/min. Phenytoin Descriptio more...