18 . February , 2019 - Monday
Check todays hot topics or new products

Find a Drug: Advanced

Please Sign in or Register

All about: Ketotifen Fumarate

Big Image Pronouncation: (KEY-toe-TIF-fen FEW-mah-rate)
Class: Ophthalmic antihistamine

Trade Names:
Zaditor
- Solution 0.025%

Mechanism of Action

Pharmacology

Inhibits release of mediators from cells involved in hypersensitivity reactions.

Pharmacokinetics

Absorption

Little systemic exposure following topical ocular administration.

Indications and Usage

Temporary prevention of itching of eyes caused by allergic conjunctivitis.

Contraindications

Standard considerations.

Dosage and Administration

Adults and children 3 yr of age and older

Ophthalmic 1 drop in affected eye(s) twice daily, every 8 to 12 h.

General Advice

  • For topical ophthalmic use only. Not for use on the skin, in the ear, or for injection into eye.
  • Ask patient to tilt head back and instill prescribed number of drops into affected eye(s) as ordered. Ask patient to close eye(s) for 2 to 3 min and apply light finger pressure to lacrimal sac for 1 to 2 min after installation. Do not touch top of dropper bottle to eye, fingers, or any other surface.
  • If using other topical ophthalmic medications, separate each medication by at least 5 min. Instill ophthalmic ointment last.

Storage/Stability

Store ophthalmic solution between 39° and 77°F. Keep tightly capped.

Drug Interactions

None well documented.

Laboratory Test Interactions

None well documented.

Adverse Reactions

CNS

Headache (10% to 25%).

EENT

Conjunctival injection, rhinitis (10% to 25%); ocular allergic reactions, burning or stinging of eye, conjunctivitis, eye discharge, dry eye, eye pain, eyelid disorder, itching eye, keratitis, lacrimation disorder, mydriasis, photophobia, rash, pharyngitis (less than 5%).

Miscellaneous

Flu syndrome (less than 5%).

Precautions

Pregnancy

Category C .

Lactation

Undetermined.

Children

Safety and efficacy not established in children younger than 3 yr of age.

Patient Information

  • Remind patient that eye drops are for use in the eye only.
  • Teach patient proper technique for instilling eye drops: Wash hands; do not allow dropper to touch eye; tilt head back and look up; pull lower eyelid down; instill prescribed number of drops; close eye for 1 to 2 min and apply gentle pressure to bridge of nose for 1 to 3 min; do not rub eye.
  • Caution patient not to touch top of dropper bottle to eye, fingers, or any other surface.
  • Advise patient that if more than 1 topical ophthalmic medication is being used to separate each medication by at least 5 min apart. Instill ophthalmic ointment last.
  • Inform patient that eye redness, headaches, and runny nose are the most common side effects and to contact health care provider if they occur and are bothersome.
  • Advise patient to contact eye doctor if eye or eyelid inflammation is noted or if eye symptoms do not improve or worsen.
  • Instruct patient wearing contact lenses to remove lenses when instilling eye drops and, if wearing soft contact lenses, to wait 10 min after instilling drops before inserting lenses.
  • Caution patient wearing contact lenses not to wear lenses if eyes are red.

Recent Drug Updates at DrugIndexOnline:





Bupropion hydrochloride Bupropion hydrochloride
Generic name: Bupropion hydrochloride Brand names: Zyban Why is Bupropion hydrochloride prescribed? Zyban is a nicotine-free quit-smoking aid. Instead of nicotine, it contains the same active ingredient as the antidepressant medication Wellbutrin. It works by boosting the levels of several chemi more...

butorphanol injection butorphanol injection
Generic Name: butorphanol (injection) (byoo TOR fa nole) Brand Names: Stadol What is butorphanol? Butorphanol is in a group of drugs called narcotic pain relievers. It is similar to morphine. Butorphanol is used to treat moderate to severe pain. It is also used as part of anesthesia fo more...

Chlor-Trimeton Decongestant Sustained-Release Tablets Chlor-Trimeton Decongestant Sustained-Release Tablets
Generic Name: Chlorpheniramine/Pseudoephedrine Sustained-Release Tablets (klor-fen-IHR-ah-meen/sue-do-eh-FED-rin) Brand Name: Examples include Biohist LA and Chlor-Trimeton DecongestantChlor-Trimeton Decongestant Sustained-Release Tablets is used for:Relieving symptoms of sinus congestion, sinu more...

Humalog Humalog
Some commonly used brand names are: In the U.S.— Humalog Category Antidiabetic agent Description Insulin lispro (IN-su-lin LYE-sproe) is a type of insulin. Insulin is one of many hormones that help the body turn the food we eat into energy. This is done by using the glucose (suga more...

Intal Inhaler Intal Inhaler
Generic Name: cromolyn sodium inhalation (KROE moe lin) Brand Names: Intal, Intal Inhaler What is Intal Inhaler (cromolyn sodium inhalation)? Cromolyn sodium is an anti-inflammatory medication. It works by preventing the release of substances in the body that cause inflammation. Cromoly more...

Lotrel Lotrel
Generic Name: Amlodipine/Benazepril (am-LOE-di-peen/ben-AZ-e-pril) Brand Name: LotrelDo not take Lotrel if you are pregnant. Lotrel can cause injury and possibly death to a developing fetus when used after the third month of pregnancy. Talk with your doctor at once if you suspect that you are more...

Pediatex-CT Chewable Tablets Pediatex-CT Chewable Tablets
Generic Name: Diphenhydramine/Phenylephrine Chewable Tablets (dye-fen-HYE-dra-meen/fen-ill-EF-rin) Brand Name: Examples include Dytan-D and Pediatex-CTPediatex-CT Chewable Tablets is used for:Temporarily relieving symptoms of hay fever, allergies, or the common cold, including nasal congestion, more...

pentobarbital pentobarbital
Generic Name: pentobarbital (pen toe BAR bi tal) Brand Names: Nembutal, Nembutal Sodium What is pentobarbital? Pentobarbital is in a class of drugs called barbiturates (bar bi TURE ates). Pentobarbital depresses the activity of your brain and nervous system. Pentobarbital is used to trea more...