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All about: Amoclan Suspension

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Generic Name: Amoxicillin/Clavulanate Suspension 200 mg/5 mL and 400 mg/5 mL (a-MOX-i-SIL-in/KLAV-ue-la-nate)
Brand Name: Examples include Amoclan and Augmentin

Amoclan Suspension is used for:

Treating infections caused by certain bacteria.

Amoclan Suspension is a penicillin antibiotic. It works by killing sensitive bacteria.

Do NOT use Amoclan Suspension if:

  • you are allergic to any ingredient in Amoclan Suspension or other penicillin antibiotics (eg, ampicillin)
  • you have a history of liver problems or yellowing of the eyes or skin caused by Amoclan Suspension
  • you have infectious mononucleosis (mono)
  • you have recently received or will be receiving live oral typhoid vaccine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Amoclan Suspension:

Some medical conditions may interact with Amoclan Suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of allergies, asthma, hay fever, or hives
  • if you have had a severe allergic reaction (eg, severe rash, hives, breathing difficulties, dizziness) to a cephalosporin (eg, cephalexin) or other beta-lactam antibiotic (eg, imipenem)
  • if you have kidney problems, phenylketonuria, or gonorrhea
  • if you have a history of liver problems or yellowing of the eyes or skin

Some MEDICINES MAY INTERACT with Amoclan Suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Anticoagulants (eg, warfarin) because the risk of bleeding may be increased
  • Probenecid because it may increase the amount of Amoclan Suspension in your blood
  • Chloramphenicol, macrolide antibiotics (eg, erythromycin), sulfonamides (eg, sulfamethoxazole), or tetracycline antibiotics (eg, doxycycline) because they may decrease Amoclan Suspension's effectiveness
  • Methotrexate because the risk of its side effects may be increased by Amoclan Suspension
  • Live oral typhoid vaccine or hormonal birth control (eg, birth control pills) because their effectiveness may be decreased by Amoclan Suspension

This may not be a complete list of all interactions that may occur. Ask your health care provider if Amoclan Suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Amoclan Suspension:

Use Amoclan Suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Amoclan Suspension by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Shake well before each use.
  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • To clear up your infection completely, take Amoclan Suspension for the full course of treatment. Keep taking it even if you feel better in a few days.
  • If you miss a dose of Amoclan Suspension, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Amoclan Suspension.

Important safety information:

  • Amoclan Suspension may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Amoclan Suspension with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Amoclan Suspension only works against bacteria; it does not treat viral infections (eg, the common cold).
  • Be sure to use Amoclan Suspension for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Long-term or repeated use of Amoclan Suspension may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
  • Hormonal birth control (eg, birth control pills) may not work as well while you are using Amoclan Suspension. To prevent pregnancy, use an extra form of birth control (eg, condoms).
  • Some of these products contain phenylalanine. If you must have a diet that is low in phenylalanine, ask your pharmacist if it is in your product.
  • Brown, yellow, or gray tooth discoloration has occurred rarely in some patients taking Amoclan Suspension. It occurred most often in children. The discoloration was reduced or removed by brushing or dental cleaning in most cases. Contact your doctor if you experience this effect.
  • Diabetes patients - Amoclan Suspension may cause the results of some tests for urine glucose to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine.
  • Lab tests, including liver function, kidney function, and complete blood cell counts, may be performed if you use Amoclan Suspension for a long period of time. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Amoclan Suspension with caution in the ELDERLY; they may be more sensitive to its effects, especially patients with kidney problems.
  • Use Amoclan Suspension with extreme caution in CHILDREN younger than 10 years old who have diarrhea or an infection of the stomach or bowel.
  • Amoclan Suspension should be used with extreme caution in CHILDREN younger than 3 months old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Amoclan Suspension while you are pregnant. Amoclan Suspension is found in breast milk. If you are or will be breast-feeding while you use Amoclan Suspension, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Amoclan Suspension:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; confusion; dark urine; fever, chills, or persistent sore throat; red, swollen, blistered, or peeling skin; seizures; severe diarrhea; stomach pain or cramps; unusual bruising or bleeding; vaginal discharge or irritation; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include decreased urination; severe nausea, vomiting, or diarrhea; stomach pain; unusual drowsiness.

Proper storage of Amoclan Suspension:

Store Amoclan Suspension in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Do not store in the bathroom. Throw away any unused medicine after 10 days. Keep Amoclan Suspension out of the reach of children and away from pets.

General information:

  • If you have any questions about Amoclan Suspension, please talk with your doctor, pharmacist, or other health care provider.
  • Amoclan Suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • Do not use Amoclan Suspension for other health conditions.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Patients should be counseled that antibacterial drugs including Amoclan Suspension should only be used to treat bacterial infections. They do not treat viral infections (eg, the common cold).

This information is a summary only. It does not contain all information about Amoclan Suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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