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All about: Loperamide/Simethicone

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Generic Name: Loperamide/Simethicone Capsules (loe-PER-a-mide/sye-METH-i-kone)
Brand Name: Imodium Advanced

Loperamide/Simethicone is used for:

Treating the symptoms of diarrhea plus bloating, pressure, and cramps from gas.

Loperamide/Simethicone is an antidiarrheal and antiflatulent combination. It works by slowing the movement of bowel contents. It also breaks up gas bubbles to make gas easier to eliminate.

Do NOT use Loperamide/Simethicone if:

  • you are allergic to any ingredient in Loperamide/Simethicone
  • you have stomach pain without diarrhea
  • you have constipation; stomach bloating; bloody stools; or dark, tarry stools.

Contact your doctor or health care provider right away if any of these apply to you.

Before using Loperamide/Simethicone :

Some medical conditions may interact with Loperamide/Simethicone . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have bloody diarrhea; mucus in your stool; fever; bowel problems (eg, inflammation, blockage, enlarged colon); or diarrhea caused by food poisoning, antibiotic use, or bacterial infection.
  • if you have AIDS or liver problems
  • if you are taking an antibiotic

Some MEDICINES MAY INTERACT with Loperamide/Simethicone . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Quinidine or ritonavir because they may increase the risk of this medicine's side effects
  • Saquinavir because its effectiveness may be decreased by Loperamide/Simethicone

This may not be a complete list of all interactions that may occur. Ask your health care provider if Loperamide/Simethicone may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Loperamide/Simethicone :

Use Loperamide/Simethicone as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Loperamide/Simethicone by mouth with or without food.
  • Drinking extra fluids is recommended while you have diarrhea. Check with your doctor if you have questions.
  • If you miss a dose of Loperamide/Simethicone , take it as soon as you remember. Continue to take it as directed by your doctor or on the package label.

Ask your health care provider any questions you may have about how to use Loperamide/Simethicone .

Important safety information:

  • Loperamide/Simethicone may cause drowsiness, dizziness, or tiredness. These effects may be worse if you take it with alcohol or certain medicines. Use Loperamide/Simethicone with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not take more than the recommended dose or use for longer than 48 hours without checking with your doctor.
  • If your diarrhea does not get better within 48 hours or if it gets worse, contact your doctor.
  • If you develop a fever, stomach bloating or swelling, or blood in your stools, contact your doctor.
  • Loperamide/Simethicone is used to treat the symptoms of diarrhea, but will not treat the condition causing the diarrhea. Check with your doctor if you have any questions or concerns about the cause of your diarrhea.
  • Caution is advised when using Loperamide/Simethicone in CHILDREN; they may be more sensitive to its effects, especially dehydration.
  • Do not use this medicine in CHILDREN younger than 6 years old without checking with the child's doctor.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Loperamide/Simethicone while you are pregnant. Loperamide/Simethicone is found in breast milk. Do not breast-feed while taking Loperamide/Simethicone .

Possible side effects of Loperamide/Simethicone :

All medicines may cause side effects, but many people have no, or minor, side effects. No COMMON side effects have been reported with this product. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); constipation; decreased urination; red, swollen, blistered, or peeling skin; stomach bloating, swelling, or pain.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include decreased urination; nausea; severe constipation or drowsiness; vomiting.

Proper storage of Loperamide/Simethicone :

Store at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Loperamide/Simethicone out of the reach of children and away from pets.

General information:

  • If you have any questions about Loperamide/Simethicone , please talk with your doctor, pharmacist, or other health care provider.
  • Loperamide/Simethicone is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Loperamide/Simethicone . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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