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All about: Lozol

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Generic Name: indapamide (in DA pa mide)
Brand Names: Lozol

What is Lozol (indapamide)?

Indapamide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Indapamide treats fluid retention (edema) in people with congestive heart failure. This medication is also used to treat high blood pressure (hypertension).

Indapamide may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Lozol (indapamide)?

Do not use this medication if you have severe kidney disease or are unable to urinate, if you have severe liver disease, if you are allergic to sulfa drugs, or if you have low potassium levels in your blood (hypokalemia).

Before using this medication, tell your doctor if you have liver disease, kidney disease, gout, lupus, or diabetes.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.

What should I discuss with my doctor before taking Lozol (indapamide)?

Do not use this medication if you have:
  • severe kidney disease or are unable to urinate;
  • severe liver disease;
  • low potassium levels in your blood (hypokalemia); or

  • if you have an allergy to sulfa drugs.

Before using indapamide, tell your doctor if you have:

  • kidney disease;
  • liver disease;
  • gout;

  • lupus; or

  • diabetes.

If you have any of these conditions, you may not be able to use indapamide, or you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether indapamide passes into breast milk or if it could cause harm to a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Lozol (indapamide)?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.

To be sure this medication is not causing harmful effects, your blood will need to be tested on a regular basis. It is important that you not miss any scheduled visits to your doctor.

Your blood and urine may both be tested if you have been vomiting or are dehydrated.

If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.

Store the tablets at room temperature away from heat, light, and moisture.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of a indapamide overdose may include nausea, weakness, dizziness, dry mouth, thirst, and muscle pain or weakness.

What should I avoid while taking Lozol (indapamide)?

Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

Lozol (indapamide) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:
  • dry mouth, thirst, nausea, vomiting;

  • feeling weak, drowsy, restless, or light-headed;

  • fast or uneven heartbeat; or

  • muscle pain or weakness.

Continue using indapamide and talk with your doctor if you have any of these less serious side effects:

  • dizziness;

  • headache; or

  • mild skin rash.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Lozol (indapamide)?

Before taking this medication, tell your doctor if you are using any of the following drugs:

  • lithium;

  • baclofen (Lioresal);

  • other blood pressure medications;

  • steroids (prednisone and others);

  • insulin or diabetes medicine taken by mouth;

  • salicylates such as aspirin, Disalcid, Doan's Pills, Dolobid, Salflex, Tricosal, and others;

  • an ACE inhibitor such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), lisinopril (Prinivil, Zestril), ramipril (Altace), and others;

  • NSAIDs (non-steroidal anti-inflammatory drugs) such as aspirin, ibuprofen (Motrin, Advil), diclofenac (Voltaren), indomethacin, naproxen (Aleve, Naprosyn), piroxicam (Feldene), and others; or

  • amiodarone (Cordarone, Pacerone), bepridil (Vascor), chloroquine (Arelan), cisapride (Propulsid), clarithromycin (Biaxin), disopyramide (Norpace), dofetilide (Tikosyn), droperidol (Inapsine), erythromycin (Erythrocin, E.E.S), haloperidol (Haldol), pentamidine (NebuPent, Pentam), pimozide (Orap), procainamide (Procan), quinidine (Cardioquin, Quinaglute), sotalol (Betapace), sparfloxacin (Zagam), or thioridazine (Mellaril).

If you are using any of these drugs, you may not be able to use indapamide, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect indapamide. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

  • Your pharmacist has additional information about indapamide written for health professionals that you may read.

What does my medication look like?

Indapamide is available with a prescription under the brand name Lozol. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

  • Lozol 1.25 mg--octagonal, orange, film-coated tablets

  • Lozol 2.5 mg--octagonal, white, film-coated tablets

  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 6.01. Revision Date: 6/13/06 10:42:50 AM.

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