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All about: Marcaine Solution

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Generic Name: Bupivacaine Injection Solution (byoo-PIV-a-kane)
Brand Name: Examples include Marcaine and Sensorcaine

Marcaine Solution is used for:

Numbing (loss of feeling) during dental or surgical procedures, labor, or delivery. It may also be used for other conditions as determined by your doctor.

Marcaine Solution is a local anesthetic. It works by blocking the generation and conduction of nerve impulses.

Do NOT use Marcaine Solution if:

  • you are allergic to any ingredient in Marcaine Solution or other similar medicines (eg, amide-type anesthetics)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Marcaine Solution:

Some medical conditions may interact with Marcaine Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have liver or kidney problems, heart disease, or blood pressure problems

Some MEDICINES MAY INTERACT with Marcaine Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Beta-blockers (eg, atenolol) or digoxin because the risk of side effects such as abnormal heartbeat may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Marcaine Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Marcaine Solution:

Use Marcaine Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Marcaine Solution will be administered as an injection at your doctor's office, hospital, or clinic.
  • If you miss a dose of Marcaine Solution, contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Marcaine Solution.

Important safety information:

  • Marcaine Solution may cause drowsiness, dizziness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Marcaine Solution. Using Marcaine Solution alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • If you are going home before the numbness wears off, protect the treated area from injury until you regain feeling. If you received Marcaine Solution for a dental procedure, do not chew gum or eat until the feeling comes back. Also be careful not to bite your tongue or the inside of your mouth.
  • Some of these products contain sulfites, which can cause allergic reactions in certain individuals (eg, asthma patients). If you have previously had allergic reactions to sulfites, contact your pharmacist to determine if the product you are taking contains sulfites.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Marcaine Solution during pregnancy. Marcaine Solution is excreted in breast milk. Do not breast-feed while taking Marcaine Solution.

Possible side effects of Marcaine Solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Mild dizziness or drowsiness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; changes in hearing; chest pain; excitement; irregular heartbeat; nausea; numbness that lasts for more than a few hours; restlessness; ringing in the ears; seizures; severe dizziness or drowsiness; tremors; vomiting.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include seizures; shortness of breath; slow heartbeat.

Proper storage of Marcaine Solution:

Store Marcaine Solution at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep Marcaine Solution out of the reach of children and away from pets.

General information:

  • If you have any questions about Marcaine Solution, please talk with your doctor, pharmacist, or other health care provider.
  • Marcaine Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Marcaine Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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