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All about: Marezine

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Generic Name: cyclizine (SYE kli zeen)
Brand Names: Marezine

What is Marezine (cyclizine)?

Cyclizine is used to relieve nausea, vomiting, and dizziness associated with motion sickness.

Cyclizine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Marezine (cyclizine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Cyclizine may cause dizziness, drowsiness, or blurred vision. If you experience dizziness, drowsiness, or blurred vision, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking cyclizine.

Who should not take Marezine (cyclizine)?

Before taking this medication, tell your doctor if you have

  • kidney or liver disease,

  • an enlarged prostate,

  • difficulty urinating,

  • bladder problems, or

  • glaucoma.

You may not be able to take cyclizine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Cyclizine is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby. Do not take cyclizine without first talking to your doctor if you are pregnant. It is not known whether cyclizine passes into breast milk. Do not take cyclizine without first talking to your doctor if you are breast-feeding a baby. Cyclizine is not recommended for use by children younger than 12 years of age.

How should I take Marezine (cyclizine)?

Take cyclizine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Cyclizine usually is taken approximately 30 minutes before travel and then every 4 to 6 hours as needed. Do not take more than 200 mg of this medication in 1 day.

Store cyclizine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a cyclizine overdose include drowsiness, agitation, excitability, seizures or convulsions, hallucinations, and death.

What should I avoid while taking Marezine (cyclizine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Cyclizine may cause dizziness, drowsiness, or blurred vision. If you experience dizziness, drowsiness, or blurred vision, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking cyclizine.

Marezine (cyclizine) side effects

Stop taking cyclizine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take cyclizine and talk to your doctor if you experience

  • drowsiness;

  • restlessness, excitation, nervousness, or insomnia;

  • blurred vision;

  • dry mouth, nose, or throat;

  • decreased appetite, nausea, or vomiting;

  • difficulty urinating; or

  • an irregular or fast heartbeat.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Marezine (cyclizine)?

Cyclizine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine unless your doctor approves.

Drugs other than those listed here may also interact with cyclizine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Where can I get more information?

  • Your pharmacist has more information about cyclizine written for health professionals that you may read.

What does my medication look like?

Cyclizine is available with a prescription and over the counter under the brand name Marezine as an injection and in 50 mg tablets. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 2.04. Revision Date: 2/13/04 4:01:37 PM.

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