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All about: Maxalt-MLT Orally Disintegrating Tablets

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Generic Name: Rizatriptan Orally Disintegrating Tablets (rye-za-TRIP-tan)
Brand Name: Maxalt-MLT

Maxalt-MLT Orally Disintegrating Tablets is used for:

Treating acute migraine headache with or without aura (flashing lights, wavy lines, dark spots) in adults. It should not be used to prevent migraines or cluster headaches.

Maxalt-MLT Orally Disintegrating Tablets is a selective serotonin receptor agonist. It works by narrowing dilated blood vessels in the brain, relieving migraine headaches.

Do NOT use Maxalt-MLT Orally Disintegrating Tablets if:

  • you are allergic to any ingredient in Maxalt-MLT Orally Disintegrating Tablets
  • you are taking ergot alkaloids (eg, ergotamine) or have taken a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the past 14 days
  • you have taken another serotonin receptor agonist (eg, sumatriptan) within the last 24 hours
  • you have a history of chest pain, blood flow or heart conditions, ischemic heart disease, irregular heartbeat, stroke, or uncontrolled high blood pressure

Contact your doctor or health care provider right away if any of these apply to you.

Before using Maxalt-MLT Orally Disintegrating Tablets:

Some medical conditions may interact with Maxalt-MLT Orally Disintegrating Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you are obese, postmenopausal, or smoke cigarettes
  • if you have basilar artery or hemiplegic migraines, or cluster headaches
  • if you have diabetes, kidney or liver problems, seizures, high cholesterol, high blood pressure, phenylketonuria (PKU), or a family history of coronary artery disease

Some MEDICINES MAY INTERACT with Maxalt-MLT Orally Disintegrating Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine) because they may decrease Maxalt-MLT Orally Disintegrating Tablets's effectivenss
  • Beta-blockers (eg, propranolol), ergot alkaloids (eg, ergotamine), or MAOIs (eg, phenelzine) because the actions and side effects of Maxalt-MLT Orally Disintegrating Tablets may be increased
  • Dexfenfluramine, ergot alkaloids (eg, ergotamine), or sibutramine because their actions and the risk of their side effects may be increased by Maxalt-MLT Orally Disintegrating Tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if Maxalt-MLT Orally Disintegrating Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Maxalt-MLT Orally Disintegrating Tablets:

Use Maxalt-MLT Orally Disintegrating Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Maxalt-MLT Orally Disintegrating Tablets. Talk to your pharmacist if you have questions about this information.
  • It is not necessary to take Maxalt-MLT Orally Disintegrating Tablets with liquid.
  • These tablets are packaged in a blister with an outer aluminum pouch. Do not remove the blister from the outer pouch until you are ready to take Maxalt-MLT Orally Disintegrating Tablets. Peel the blister pack open with dry hands and place the tablet on your tongue. The tablet will dissolve and it can be swallowed with saliva.
  • Take a single dose of Maxalt-MLT Orally Disintegrating Tablets as soon as migraine symptoms appear. A second dose may be taken if there is only a partial response or symptoms of the migraine return. However, do not take it sooner than 2 hours following the first dose. Do not take more than 30 milligrams (mg) in a 24-hour period.
  • Do not take additional doses if you do not get a response from the first dose.
  • If you miss a dose of Maxalt-MLT Orally Disintegrating Tablets and you still have a headache, follow your doctor's dosing instructions. Contact your doctor immediately if you are unsure of what to do if you miss a dose. Do not take Maxalt-MLT Orally Disintegrating Tablets more often than prescribed. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Maxalt-MLT Orally Disintegrating Tablets.

Important safety information:

  • Maxalt-MLT Orally Disintegrating Tablets may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Maxalt-MLT Orally Disintegrating Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Maxalt-MLT Orally Disintegrating Tablets is not intended to prevent or reduce the number of migraine attacks that you experience.
  • If you have a headache that is different than your usual migraine attacks, check with your doctor before using Maxalt-MLT Orally Disintegrating Tablets.
  • Phenylketonuria patients - Some of these products contain phenylalanine. If you must have a diet that is low in phenylalanine, ask your pharmacist if it is in your product.
  • Diabetes patients - Maxalt-MLT Orally Disintegrating Tablets may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Maxalt-MLT Orally Disintegrating Tablets should not be used in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Maxalt-MLT Orally Disintegrating Tablets while you are pregnant. It is not known if Maxalt-MLT Orally Disintegrating Tablets is found in breast milk. If you are or will be breast-feeding while you use Maxalt-MLT Orally Disintegrating Tablets, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Maxalt-MLT Orally Disintegrating Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; drowsiness; fatigue; nausea; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody diarrhea; changes in vision; chest pain, heaviness, or pressure; cold, tingling, or numb hands or feet; fainting or unsteadiness; fast or irregular heartbeat; pain or tightness in jaw or neck; stomach pain; unusual weakness.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include slow, fast, or irregular heartbeat; unusual dizziness or drowsiness; vomiting.

Proper storage of Maxalt-MLT Orally Disintegrating Tablets:

Store Maxalt-MLT Orally Disintegrating Tablets at room temperature, between 59 to 86 degrees F (15 to 30 degrees C). Store away from heat, light, and moisture. Keep Maxalt-MLT Orally Disintegrating Tablets in the blister with the outer aluminum pouch until ready to use. Keep Maxalt-MLT Orally Disintegrating Tablets out of the reach of children and away from pets.

General information:

  • If you have any questions about Maxalt-MLT Orally Disintegrating Tablets, please talk with your doctor, pharmacist, or other health care provider.
  • Maxalt-MLT Orally Disintegrating Tablets is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Maxalt-MLT Orally Disintegrating Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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