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All about: Methylin Chewable Tablets

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Generic Name: Methylphenidate Chewable Tablets (meth-il-FEN-i-date)
Brand Name: Methylin

Use Methylin Chewable Tablets with caution if you have a history of emotional problems, or alcohol or substance abuse. Abuse of Methylin Chewable Tablets may cause it to not work as well. Abuse may also lead to addiction and severe mental changes. Do not suddenly stop using Methylin Chewable Tablets. Depression and other mental problems may occur. Your doctor should slowly lower your dose over a period of time if you need to stop using it.


Methylin Chewable Tablets is used for:

Treating attention deficit disorder (ADD). It is also used to treat uncontrollable periods of daytime sleep (narcolepsy). It may also be used for other conditions as determined by your doctor.

Methylin Chewable Tablets is a central nervous system stimulant. Exactly how it works is not known.

Do NOT use Methylin Chewable Tablets if:

  • you are allergic to any ingredient in Methylin Chewable Tablets
  • you have severe anxiety, agitation, or tension
  • you have glaucoma
  • you have motor tics (involuntary movements), Tourette syndrome, or a family history of Tourette syndrome
  • you have serious heart problems (eg, heart defect, irregular heartbeat)
  • you have trouble swallowing
  • you are taking a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) or have taken an MAOI within the past 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Methylin Chewable Tablets:

Some medical conditions may interact with Methylin Chewable Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of high blood pressure, heart problems (eg, heart failure, fast or irregular heartbeat), or recent heart attack, or if a family member has a history of irregular heartbeat or sudden death
  • if you have a history of seizures or abnormal electroencephalograms (EEGs)
  • if you have a history of overactive thyroid, chronic fatigue, cystic fibrosis, narrowing of the esophagus, stomach or bowel problems (eg, blockage, inflammation, narrowing), or phenylketonuria
  • if you have a history of mood or mental problems (eg, agitation, anxiety, bipolar disorder, depression, psychosis, tension), abnormal thoughts, hallucinations, suicidal thoughts or attempts, or alcohol or other substance abuse or dependence, or if a family member has a history of any of these problems

Some MEDICINES MAY INTERACT with Methylin Chewable Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • MAOIs (eg, phenelzine) because severe high blood pressure may occur
  • Clonidine because serious side effects may occur
  • Pressor agents (eg, norepinephrine) because the risk of high blood pressure may be increased
  • Anticoagulants (eg, warfarin), certain anticonvulsants (eg, phenobarbital, phenytoin, primidone), phenylbutazone, selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), or tricyclic antidepressants (eg, imipramine) because the risk of their side effects may be increased by Methylin Chewable Tablets
  • Guanethidine or other medicines for high blood pressure because their effectiveness may be decreased by Methylin Chewable Tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if Methylin Chewable Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Methylin Chewable Tablets:

Use Methylin Chewable Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Methylin Chewable Tablets comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Methylin Chewable Tablets refilled.
  • Take Methylin Chewable Tablets by mouth 30 to 45 minutes before eating unless your doctor tells you otherwise.
  • Chew Methylin Chewable Tablets well before swallowing.
  • Take Methylin Chewable Tablets with a full glass of water or other liquid (8 oz/240 mL).
  • You may have trouble sleeping while taking Methylin Chewable Tablets. If this occurs, taking your last dose before 6 pm may help. Check with your doctor before you change the way that you take Methylin Chewable Tablets. If trouble sleeping continues, talk with your doctor.
  • If you miss a dose of Methylin Chewable Tablets, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Methylin Chewable Tablets.

Important safety information:

  • Methylin Chewable Tablets may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Methylin Chewable Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do NOT take more than the recommended dose without checking with your doctor.
  • If your symptoms do not get better within 1 month or if they get worse, check with your doctor.
  • Serious effects, including heart attack, stroke, and sudden death, have occurred with the use of stimulant medicines in patients with heart defects or other serious heart problems. If you have a heart defect or other serious problem, talk with your doctor about other therapies to treat your condition.
  • If you take Methylin Chewable Tablets without enough liquid, it may swell and block your throat. Be sure to take Methylin Chewable Tablets with a full glass (8 oz/240 mL) of water or other liquid. Do not take Methylin Chewable Tablets if you have trouble swallowing. If you take Methylin Chewable Tablets and then experience chest pain, vomiting or trouble swallowing or breathing, seek medical care at once.
  • Some of these products contain phenylalanine. If you must have a diet that is low in phenylalanine, ask your pharmacist if it is in your product.
  • Lab tests, including blood pressure, heart function, complete blood cell counts, and platelet counts, may be performed while you use Methylin Chewable Tablets. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Methylin Chewable Tablets may affect growth rate and weight gain in CHILDREN and teenagers in some cases. They may need regular growth and weight checks while they take Methylin Chewable Tablets.
  • Caution is advised when using Methylin Chewable Tablets in CHILDREN; they may be more sensitive to its effects, especially loss of appetite, stomach pain, weight loss, trouble sleeping, and fast heartbeat.
  • Methylin Chewable Tablets should not be used in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Methylin Chewable Tablets while you are pregnant. It is not known if Methylin Chewable Tablets is found in breast milk. If you are or will be breast-feeding while you use Methylin Chewable Tablets, check with your doctor. Discuss any possible risks to your baby.

When used for long periods of time or at high doses, Methylin Chewable Tablets may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Methylin Chewable Tablets stops working well. Do not take more than prescribed.

Some people who use Methylin Chewable Tablets for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction. Do not suddenly stop taking Methylin Chewable Tablets. If you do, you may have WITHDRAWAL symptoms. These may include depression or other mental problems. If you need to stop Methylin Chewable Tablets, your doctor will lower your dose over time.

Possible side effects of Methylin Chewable Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; headache; loss of appetite; nausea; nervousness; stomach pain; trouble sleeping.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; joint pain; purple or brownish red spots on the skin); behavior changes (eg, aggression, hostility); blurred vision or other vision problems; chest pain; confusion; dark urine; fainting; fast or irregular heartbeat; fever, chills, or sore throat; hallucinations; mental or mood changes (eg, agitation, anxiety, depression, irritability, persistent crying, unusual sadness); seizures; severe or persistent dizziness or headache; suicidal thoughts or attempts; uncontrolled speech or muscle movements; yellowing of the eyes or skin.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include confusion; dilated pupils; fast or irregular heartbeat; fever; flushing; hallucinations; loss of consciousness; muscle twitching; seizures; severe or persistent headache; tremors; unusual sweating; vomiting.

Proper storage of Methylin Chewable Tablets:

Store Methylin Chewable Tablets between 68 and 77 degrees (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Methylin Chewable Tablets out of the reach of children and away from pets.

General information:

  • If you have any questions about Methylin Chewable Tablets, please talk with your doctor, pharmacist, or other health care provider.
  • Methylin Chewable Tablets is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Methylin Chewable Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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