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All about: Milrinone

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Generic Name: Milrinone (MILL-ri-none)
Brand Name: Primacor

Milrinone is used for:

Treating congestive heart failure.

Milrinone is an inotrope and vasodilator. It works by increasing the force with which the heart pumps blood through the body and widens blood vessels, which allows blood to flow through the body more easily.

Do NOT use Milrinone if:

  • you are allergic to any ingredient in Milrinone
  • you have severe blockage of your aorta or certain heart valve problems (pulmonic valvular disease), or you have recently had a heart attack

Contact your doctor or health care provider right away if any of these apply to you.

Before using Milrinone :

Some medical conditions may interact with Milrinone . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of kidney problems, irregular heartbeat or other heart problems (eg, hypertrophic cardiomyopathy), heart attack, or heart valve conditions

Some MEDICINES MAY INTERACT with Milrinone . However, no specific interactions with Milrinone are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Milrinone may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Milrinone :

Use Milrinone as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Milrinone is usually administered as an injection at your doctor's office, hospital, or clinic.
  • If you miss a dose of Milrinone , contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Milrinone .

Important safety information:

  • Milrinone may cause dizziness or lightheadedness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Milrinone . Using Milrinone alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Milrinone may cause dizziness, lightheadedness, or fainting. Alcohol, hot weather, exercise, and fever can increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of dizziness, lightheadedness, or weakness.
  • LAB TESTS, including heart function, kidney function, blood electrolytes, and blood pressure, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Milrinone with extreme caution in CHILDREN. Safety and effectiveness have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Milrinone during pregnancy. It is unknown if Milrinone is excreted in breast milk. If you are or will be breast-feeding while you are using Milrinone , check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Milrinone :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; headache.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; fast or irregular heartbeat; severe dizziness or lightheadedness.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include severe dizziness or lightheadedness.

Proper storage of Milrinone :

Milrinone is usually handled and stored by a health care provider. If you are using Milrinone at home, store Milrinone as directed by your pharmacist or health care provider.

General information:

  • If you have any questions about Milrinone , please talk with your doctor, pharmacist, or other health care provider.
  • Milrinone is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Milrinone . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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