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All about: Molindone hydrochloride

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Generic name: Molindone hydrochloride
Brand names: Moban

Why is Molindone hydrochloride prescribed?

Moban is used in the treatment of schizophrenia, the crippling psychological disorder that causes its victims to lose touch with reality, often triggering hallucinations, delusions, and disorganized thought.

Most important fact about Molindone hydrochloride

Moban can cause tardive dyskinesia, a condition marked by involuntary movements in the face and body, including chewing movements, puckering, puffing the cheeks, and sticking out the tongue. This condition may be permanent and appears to be most common among the elderly, especially elderly women. Ask your doctor for more information about this possible risk.

How should you take Molindone hydrochloride?

Take Moban exactly as prescribed. Do not take with alcohol.

--If you miss a dose...

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.

--Storage instructions...

Store at room temperature. Protect from light.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Moban.

  • More common side effects may include:
    Blurred vision, depression, drowsiness (especially at the start of therapy), dry mouth, euphoria, hyperactivity, nausea, Parkinson's--like movements, restlessness

Why should Molindone hydrochloride not be prescribed?

Moban should not be combined with alcohol, barbiturates (sleep aids), narcotics (painkillers), or other substances that slow down the nervous system, nor should it be given to anyone in a comatose state. Moban cannot be used by anyone who is hypersensitive to the drug. The concentrate form of Moban contains a sulfite that may cause life-threatening allergic reactions in some people, especially in those with asthma.

Special warnings about Molindone hydrochloride

Drugs such as Moban can cause a potentially fatal condition called Neuroleptic Malignant Syndrome (NMS). Symptoms include high fever, rigid muscles, irregular pulse or blood pressure, rapid heartbeat, excessive perspiration, and changes in heart rhythm. If you develop these symptoms, contact your doctor immediately. Moban should be discontinued.

Moban should be used with caution if you have ever had breast cancer. The drug stimulates production of a hormone that promotes the growth of certain types of tumors.

Because Molindone hydrochloride may cause drowsiness, do not participate in activities that require full alertness, such as driving or operating machinery, until you are sure how this medicine affects you.

Moban may mask signs of a brain tumor or intestinal blockage. It causes increased activity in some people. On rare occasions, it causes seizures.

Possible food and drug interactions when taking Molindone hydrochloride

Remember that Moban must never be combined with alcohol, barbiturates, or narcotics. In addition, Moban tablets contain calcium, which may interfere with the absorption of tetracycline antibiotics (Achromycin V, Sumycin) and phenytoin (Dilantin).

Special information if you are pregnant or breastfeeding

The safety and effectiveness of Moban during pregnancy have not been adequately studied. If you are pregnant or planning to become pregnant, tell your doctor immediately. Moban should be used during pregnancy only if the benefits outweigh the potential risks.

It is not known whether Moban appears in breast milk. Check with your doctor before deciding to breastfeed.

Recommended dosage


The usual starting dose is 50 to 75 milligrams a day. Your doctor may increase the dose to 100 milligrams a day after 3 or 4 days of treatment.

The long-term maintenance dose depends on your body's response to the medication. The usual maintenance dose for treatment of mild symptoms is 5 milligrams to 15 milligrams taken 3 or 4 times a day. For moderate symptoms it is 10 milligrams to 25 milligrams taken 3 or 4 times a day. For severe symptoms, up to 225 milligrams a day may be prescribed. Older adults generally take lower dosages of Moban.


The safety and effectiveness of Moban in children under age 12 have not been established.


Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical help immediately.

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