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All about: Mytrex

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Generic name: Nystatin, Triamcinolone acetonide
Brand names: Mytrex, Myco-Triacet II, Mycolog-II

Why is Mytrex prescribed?

Mycolog-II Cream and Ointment are prescribed for the treatment of candidiasis (a yeast-like fungal infection) of the skin. The combination of an antifungal (nystatin) and a steroid (triamcinolone acetonide) provides greater benefit than nystatin alone during the first few days of treatment. Nystatin kills the fungus or prevents its growth; triamcinolone helps relieve the redness, swelling, itching, and other discomfort that can accompany a skin infection.

Most important fact about Mytrex

Absorption of Mytrex through the skin can affect the whole body instead of just the surface of the skin being treated. Although unusual, it is possible that you could experience symptoms of steroid excess such as weight gain, reddening and rounding of the face and neck, growth of excess body and facial hair, high blood pressure, emotional disturbances, increased blood sugar, and urinary excretion of glucose (marked by an increase in frequency of urination).

Use of Mytrex over large surface areas, for prolonged periods, or with airtight dressings or bandages, could cause these problems. Your doctor will watch your condition and periodically check for symptoms.

How should you use Mytrex?

Use this medicine for the full course of treatment, even if your symptoms are gone. Apply a thin layer to the affected area and gently rub it in. Do not bandage or wrap the area being treated, unless your doctor tells you to. Keep the area cool and dry.

Use Mytrex exactly as prescribed by your doctor. Do not use it more often or for a longer time. It is for external use only. Avoid contact with the eyes.

--If you miss a dose...

Apply it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule.

--Storage instructions...

Store away from heat and light. Do not freeze.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Mycolog-II.

  • More common side effects may include:
    Blistering, burning, dryness, eruptions resembling acne, excessive discoloring of the skin, excessive growth of hair (especially on the face), hair loss (especially on the scalp), inflammation around the mouth, inflammation of hair follicles, irritation, itching, peeling, prickly heat, reddish purple lines on skin, secondary infection, severe inflammation of the skin, softening of the skin, stretch marks, stretching or thinning of the skin

Why should Mytrex not be prescribed?

If you are sensitive to or have ever had an allergic reaction to nystatin, triamcinolone acetonide, or other antifungals or steroids, you should not take Mytrex. Make sure your doctor is aware of any drug reactions you have experienced.

Special warnings about Mytrex

Do not use Mytrex for any disorder other than the one for which it was prescribed.

Remember to avoid wrapping or bandaging the affected area. The use of tight-fitting diapers or plastic pants is not recommended for a child being treated in the diaper area with Mycolog-II. These garments may act in the same way as airtight dressings or bandages.

If an irritation or allergic reaction develops while using Mycolog-II, notify your doctor.

If used in the groin area, apply Mycolog-II sparingly and wear loose-fitting clothing.

If your condition does not show improvement after 2 to 3 weeks, or if it gets worse, consult your doctor.

Possible food and drug interactions when taking Mytrex

No interactions have been reported.

Special information if you are pregnant or breastfeeding

The effects of Mycolog-II in pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor before using Mycolog-II.

It is not known whether Mytrex appears in breast milk. If Mytrex is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with Mytrex is finished.

Recommended dosage


Mycolog-II Cream

Mycolog-II Cream is usually applied to the affected areas 2 times a day, in the morning and evening, by gently and thoroughly massaging the preparation into the skin. Your doctor will have you stop using the cream if your symptoms persist after 25 days of treatment.

Mycolog-II Ointment

A thin film of Mycolog-II Ointment is usually applied to the affected areas 2 times a day, in the morning and the evening. Your doctor will have you stop using the ointment if your symptoms persist after 25 days of treatment.


Your doctor will limit use of Mycolog-II for children to the least amount that is effective. Long-term treatment may interfere with the growth and development of children.


An acute overdosage is unlikely with the use of Mycolog-II; however, long-term or prolonged use can produce reactions throughout the body. See "Most important fact about Mytrex."

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