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All about: Neomycin/Polymyxin B/Prednisolone Drops

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Generic Name: Neomycin/Polymyxin B/Prednisolone Eye Drops (NEE-oh-MYE-sin/POL-ee-MIX-in/pred-NIS-oh-lone)
Brand Name: Poly-Pred

Neomycin/Polymyxin B/Prednisolone Drops is used for:

Treating infections and relieving the redness, irritation, and discomfort associated with certain eye problems.

Neomycin/Polymyxin B/Prednisolone Drops is an antibiotic and steroid combination. It works by inhibiting the growth of bacteria and decreasing inflammation.

Do NOT use Neomycin/Polymyxin B/Prednisolone Drops if:

  • you are allergic to any ingredient in Neomycin/Polymyxin B/Prednisolone Drops
  • you have certain eye infections (eg, herpes simplex, tuberculosis, fungal, mycobacterial, or viral infections), chickenpox, or an infection due to smallpox vaccination (vaccinia)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Neomycin/Polymyxin B/Prednisolone Drops:

Some medical conditions may interact with Neomycin/Polymyxin B/Prednisolone Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have diabetes, glaucoma, optic nerve damage, or thinning of the cornea or other eye tissues

Some MEDICINES MAY INTERACT with Neomycin/Polymyxin B/Prednisolone Drops. Because little, if any, of Neomycin/Polymyxin B/Prednisolone Drops is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Neomycin/Polymyxin B/Prednisolone Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Neomycin/Polymyxin B/Prednisolone Drops:

Use Neomycin/Polymyxin B/Prednisolone Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Shake well before each use.
  • To use Neomycin/Polymyxin B/Prednisolone Drops in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
  • To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.
  • If your doctor prescribed more than 1 eye medicine, ask the best order for using each medicine.
  • Do not wear contact lenses while you are using Neomycin/Polymyxin B/Prednisolone Drops. Take care of your contact lenses as directed by the manufacturer. Check with your doctor before you use them.
  • If you miss a dose of Neomycin/Polymyxin B/Prednisolone Drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Neomycin/Polymyxin B/Prednisolone Drops.

Important safety information:

  • Neomycin/Polymyxin B/Prednisolone Drops may cause blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Neomycin/Polymyxin B/Prednisolone Drops with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do NOT use more than the recommended dose or use for longer than 10 days or for future eye problems without checking with your doctor.
  • LAB TESTS, such as eye exams, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Neomycin/Polymyxin B/Prednisolone Drops while you are pregnant. It is not known if Neomycin/Polymyxin B/Prednisolone Drops is found in breast milk. If you are or will be breast-feeding while you use Neomycin/Polymyxin B/Prednisolone Drops, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Neomycin/Polymyxin B/Prednisolone Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; temporary burning or stinging.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; continued or worsening itching, swelling, or irritation; continuing blurred vision; discharge from eyes; eye pain.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Neomycin/Polymyxin B/Prednisolone Drops:

Store Neomycin/Polymyxin B/Prednisolone Drops at room temperature, below 77 degrees F (25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not freeze. Do not store in the bathroom. Keep Neomycin/Polymyxin B/Prednisolone Drops out of the reach of children and away from pets.

General information:

  • If you have any questions about Neomycin/Polymyxin B/Prednisolone Drops, please talk with your doctor, pharmacist, or other health care provider.
  • Neomycin/Polymyxin B/Prednisolone Drops is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Neomycin/Polymyxin B/Prednisolone Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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