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All about: Olsalazine

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Generic Name: Olsalazine Capsules (OLE-SAL-uh-zeen)
Brand Name: Dipentum

Olsalazine is used for:

Controlling symptoms of ulcerative colitis in patients who cannot take sulfasalazine.

Olsalazine is a salicylate. It works by reducing inflammation of the colon by possibly preventing the production of substances that cause this inflammation.

Do NOT use Olsalazine if:

  • you are allergic to any ingredient in Olsalazine
  • you are allergic to aspirin or medications similar to aspirin (eg, salicylates)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Olsalazine :

Some medical conditions may interact with Olsalazine . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have kidney problems

Some MEDICINES MAY INTERACT with Olsalazine . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Thiopurines (eg, azathioprine) or anticoagulants (eg, warfarin) because their actions and side effects, including increased risk of bone marrow toxicity or bleeding, may be increased by Olsalazine

This may not be a complete list of all interactions that may occur. Ask your health care provider if Olsalazine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Olsalazine :

Use Olsalazine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Olsalazine with food.
  • Take Olsalazine in evenly divided doses.
  • Continue using Olsalazine for the full course of treatment even if you feel better in a few days.
  • If you miss a dose of Olsalazine , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. If more than one dose is missed, contact your doctor or pharmacist.

Ask your health care provider any questions you may have about how to use Olsalazine .

Important safety information:

  • If diarrhea occurs while taking Olsalazine , contact your health care provider.
  • If your symptoms do not improve or if they worsen after you start using Olsalazine , check with your doctor.
  • Olsalazine is not recommended for use in CHILDREN; safety and effectiveness have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Olsalazine during pregnancy. It is unknown if Olsalazine is excreted in breast milk. If you are or will be breast-feeding while you are using Olsalazine , check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Olsalazine :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Headache; joint pain; nausea; stomach pain/cramps; upset stomach.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); diarrhea; trouble urinating.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include decreased motor activity; diarrhea.

Proper storage of Olsalazine :

Store Olsalazine in a tightly closed container at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Olsalazine out of the reach of children and away from pets.

General information:

  • If you have any questions about Olsalazine , please talk with your doctor, pharmacist, or other health care provider.
  • Olsalazine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Olsalazine . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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