20 . August , 2018 - Monday
Check todays hot topics or new products

Find a Drug: Advanced

Please Sign in or Register

All about: PCE

Big Image
Generic Name: Erythromycin Tablets (Polymer-Coated Particles) (eh-RITH-roe-MYE-sin)
Brand Name: PCE

PCE is used for:

Treating infections caused by certain bacteria. It is also used to prevent bacterial endocarditis and attacks of rheumatic fever. It may also be used for other conditions as determined by your doctor.

PCE is a macrolide antibiotic. Macrolide antibiotics slow the growth of, or sometimes kill, sensitive bacteria by reducing the production of important proteins needed by the bacteria to survive.

Do NOT use PCE if:

  • you are allergic to any ingredient in PCE
  • you are taking astemizole, cisapride, cyclosporine, diltiazem, dofetilide, ergot alkaloids (eg, ergotamine), HIV protease inhibitors (eg, ritonavir), imidazoles (eg, ketoconazole), pimozide, QT prolonging agents (eg, quinidine, sotalol), quinolones (eg, ciprofloxacin), streptogramins (eg, quinupristin/dalfopristin), sumatriptan, terfenadine, or verapamil

Contact your doctor or health care provider right away if any of these apply to you.

Before using PCE :

Some medical conditions may interact with PCE . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have diarrhea or a stomach or intestinal infection
  • if you have a history of kidney or liver disease, heart problems, fast or irregular heartbeat, myasthenia gravis, or the blood disorder porphyria

Some MEDICINES MAY INTERACT with PCE . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Efavirenz or rifampin because they may decrease PCE 's effectiveness
  • Arsenic, cimetidine,diltiazem,dofetilide,HIV protease inhibitors (eg, ritonavir), imidazoles (eg, ketoconazole), pimozide,QT-prolonging agents (eg, quinidine, sotalol), quinolones (eg, ciprofloxacin), streptogramins (eg, quinupristin/dalfopristin ), or verapamil because side effects, such as heart toxicity or irregular heartbeat, may occur
  • Anticoagulants (eg, warfarin), aldosterone blockers (eg, spironolactone), alfentanil, arsenic, astemizole, benzodiazepines (eg, alprazolam), bromocriptine, buspirone, carbamazepine, cilostazol, cisapride, clozapine, corticosteroids (eg, hydrocortisone), cyclosporine, digitoxin, digoxin, disopyramide, ergot alkaloids (eg, ergotamine), felodipine, H1 antagonists (eg, diphenhydramine), HMG-CoA reductase inhibitors (eg, lovastatin), imatinib, macrolide immunosuppressants (eg, tacrolimus), meglitinide antidiabetics (eg, repaglinide), midazolam, phosphodiesterase type 5 inhibitors (eg, sildenafil), pimozide, QT-prolonging agents (eg, quinidine, sotalol), quinolones (eg, ciprofloxacin), rifampin, serotonin reuptake inhibitors (eg, fluoxetine), sumatriptan, theophyllines, tricyclic antidepressants (eg, amitriptyline), valproic acid, or vinca alkaloids (eg, vincristine) because the risk of their side effects may increased by PCE

This may not be a complete list of all interactions that may occur. Ask your health care provider if PCE may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use PCE :

Use PCE as directed by your doctor. Check the label on the medicine for exact dosing instructions. Check the label on the medicine for exact dosing instructions.

  • Take PCE by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Swallow PCE whole. Do not break, crush, or chew before swallowing.
  • Do not eat grapefruit or drink grapefruit juice while you use PCE .
  • PCE works best if taken at the same times each day.
  • To clear up your infection completely, take PCE for the full course of treatment. Keep taking it even if you feel better in a few days.
  • If you miss a dose of PCE , take it as soon as possible. If it is almost time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use PCE .

Important safety information:

  • Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
  • PCE only works against bacteria; it does not treat viral infections (eg, the common cold).
  • Be sure to use PCE for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Long-term or repeated use of PCE may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Lab tests, including liver function, kidney function, and complete blood cell counts, may be performed while you use PCE . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using PCE while you are pregnant. PCE is found in breast milk. If you are or will be breast-feeding while you use PCE , check with your doctor. Discuss any possible risks to your baby.

Possible side effects of PCE :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; loss of appetite; nausea; stomach pain; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; hearing changes; irregular heartbeat; red, swollen, or blistered skin; severe diarrhea; severe stomach pain or cramps; yellowing of skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of PCE :

Store PCE at room temperature, below 86 degrees F (30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep tightly closed. Keep PCE out of the reach of children and away from pets.

General information:

  • If you have any questions about PCE , please talk with your doctor, pharmacist, or other health care provider.
  • PCE is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about PCE . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

Recent Drug Updates at DrugIndexOnline:





Bonamine Bonamine
Some commonly used brand names are: In the U.S.— Antivert 3 Antivert/25 3 Antivert/50 3 Bonine 3 Dramamine II 3 Marezine 2 Meclicot 3 Medivert 3 In Canada— Bonamine 3 Marzine 2 Note: For quick reference, the following medicines are numbered to match the corresponding brand n more...

Comtrex Multi-Symptom Maximum Strength Non-Drowsy Caplets Comtrex Multi-Symptom Maximum Strength Non-Drowsy Caplets
Some commonly used brand names are: In the U.S.— Alka-Seltzer Plus Cold and Cough 21 Alka-Seltzer Plus Cold and Cough Medicine Liqui-Gels 34 Alka-Seltzer Plus Night-Time Cold Liqui-Gels 35 Ami-Tex LA 69 Anatuss LA 70 Benylin Expectorant 54 Bromfed-DM 17 Broncholate 68 Carbinoxamine Compou more...

Doxycin Doxycin
Some commonly used brand names are: In the U.S.— Achromycin V 5 Declomycin 1 Doryx 2 Dynacin 3 Minocin 3 Monodox 2 Terramycin 4 Vibramycin 2 Vibra-Tabs 2 In Canada— Alti-Doxycycline 2 Alti-Minocycline 3 Apo-Doxy 2 Apo-Doxy-Tabs 2 Apo-Minocycline 3 Apo-Tetra 5 Declomycin 1 Doxycin more...

Fosphenytoin Fosphenytoin
Pronouncation: (FOSS-FEN-ih-toe-in) Class: Anticonvulsant, Hydantoin Trade Names: Cerebyx - Injection 150 mg (100 mg phenytoin sodium) - Injection 750 mg (500 mg phenytoin sodium) Mechanism of Action Pharmacology Fosphenytoin is a prodrug, which is converted to the active metabolite phenytoin. Appe more...

Isoflurane Isoflurane
Dosage Form: Liquid for inhalation Liquid for Inhalation Rx only Isoflurane Description Isoflurane, USP, a nonflammable liquid administered by vaporizing, is a general inhalation anesthetic drug. It is 1-chloro-2,2,2-trifluoroethyl difluoromethyl ether, and its structural formula is: Some phys more...

mycophenolic acid mycophenolic acid
Generic Name: mycophenolic acid (my koe PHEH no lic ah SID) Brand Names: Myfortic What is mycophenolic acid? Mycophenolic acid is an immunosuppressant. Immunosuppressants decrease the actions of the body's immune system. Mycophenolic acid is used to prevent the body from rejecting a kidn more...

nicardipine nicardipine
Generic Name: nicardipine (nye KAR de peen) Brand Names: Cardene, Cardene SR What is nicardipine? Nicardipine is in a class of drugs called calcium channel blockers. Nicardipine relaxes (widens) your blood vessels, which makes it easier for the heart to pump and reduces its workload. Nic more...

Nystop Nystop
Generic Name: nystatin topical (nye STAT in) Brand Names: Mycostatin Topical, Nystop, Pedi-Dri What is Nystop (nystatin topical)? Nystatin topical is an antifungal medication. Nystatin topical prevents fungus from growing on your skin. Nystatin topical is used to treat skin infections c more...