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All about: Peganone

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Generic Name: Ethotoin (ETH-oh-toin)
Brand Name: Peganone

Peganone is used for:

Treating certain types of seizures. It may also be used for other conditions as determined by your doctor.

Peganone is a hydantoin anticonvulsant. It works by reducing the spread of seizure activity in the brain.

Do NOT use Peganone if:

  • you are allergic to any ingredient in Peganone
  • you have liver problems or blood problems (eg, porphyria)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Peganone :

Some medical conditions may interact with Peganone . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of alcohol abuse or dependence

Some MEDICINES MAY INTERACT with Peganone . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Antineoplastics (eg, cyclophosphamide), corticosteroids (eg, prednisone), diazoxide, folic acid, or rifampin because they may decrease Peganone 's effectiveness
  • Amiodarone, benzodiazepines (eg, alprazolam), carbamazepine, chloramphenicol, cimetidine, disulfiram, felbamate, fluconazole, fluoxetine, isoniazid, phenacemide, phenylbutazones (eg, sulfinpyrazone), stiripentol, sulfonamides (eg, sulfamethoxazole), sulthiame, ticlopidine, trimethoprim, or valproic acid because the risk of loss of coordination and involuntary eye movements may be increased
  • Primidone because the risk of its side effects may be increased by Peganone
  • Anticoagulants (eg, warfarin), cyclosporine, disopyramide, doxycycline, estrogens (eg, estradiol), gefitinib, hormonal contraceptives (eg, birth control pills), itraconazole, mexiletine, progestins (eg, medroxyprogesterone), psoralens (eg, methoxsalen), quetiapine, quinidine, or tetracyclic antidepressants (eg, mirtazapine) because their effectiveness may be decreased by Peganone
  • Immune globulin because an unexpected allergic reaction may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Peganone may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Peganone :

Use Peganone as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Peganone by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Continue to take Peganone even if you feel well. Do not miss any doses.
  • If you miss a dose of Peganone , take it as soon as possible. If it is within 4 hours of your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. If you miss doses for 2 or more days in a row or you have questions about the dose, check with your doctor as soon as possible.

Ask your health care provider any questions you may have about how to use Peganone .

Important safety information:

  • Peganone may cause dizziness or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Peganone with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol while taking Peganone unless you have discussed it with your doctor.
  • Proper dental care is important while you are taking Peganone . Brush and floss your teeth and visit the dentist regularly.
  • Tell your doctor or dentist that you take Peganone before you receive any medical or dental care, emergency care, or surgery.
  • Carry an ID card at all times that says you take Peganone .
  • Hormonal birth control (eg, birth control pills) may not work as well while you are using Peganone . To prevent pregnancy, use an extra form of birth control (eg, condoms).
  • Lab tests, including liver function, complete blood cell counts, and urine tests, may be performed while you use Peganone . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • PREGNANCY and BREAST-FEEDING: Peganone may cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Peganone while you are pregnant. Peganone is found in breast milk. Do not breast-feed while taking Peganone .

Possible side effects of Peganone :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision or other vision changes; chest pain; clumsiness or unsteadiness; fever, chills, or sore throat; general body discomfort; headache; joint pain; loss of coordination; nosebleed; numbness; reddened, swollen, or blistered skin; slurred speech; small red spots under the skin; swollen glands; trouble sleeping; unusual bruising or bleeding; unusual eye movements; unusual weakness or fatigue; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include drowsiness; loss of consciousness; loss of coordination; severe or persistent nausea; vision changes.

Proper storage of Peganone :

Store Peganone below 77 degrees F (25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Peganone out of the reach of children and away from pets.

General information:

  • If you have any questions about Peganone , please talk with your doctor, pharmacist, or other health care provider.
  • Peganone is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Peganone . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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