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All about: Polymyxin B sulfate, Neomycin sulfate, Hydrocortisone

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Generic name: Polymyxin B sulfate, Neomycin sulfate, Hydrocortisone
Brand names: Cortisporin Ophthalmic Suspension

Why is Polymyxin B sulfate, Neomycin sulfate, Hydrocortisone prescribed?

Cortisporin Ophthalmic Suspension is a combination of the steroid drug, hydrocortisone, and two antibiotics. It is prescribed to relieve inflammatory conditions such as irritation, swelling, redness, and general eye discomfort, and to treat superficial bacterial infections of the eye.

Most important fact about Polymyxin B sulfate, Neomycin sulfate, Hydrocortisone

Prolonged use of Polymyxin B sulfate, Neomycin sulfate, Hydrocortisone may increase pressure within the eye, leading to potential damage to the optic nerve and visual problems. Prolonged use also may suppress your immune response and thus increase the hazard of secondary eye infections. Your doctor should measure your eye pressure periodically if you are using this product for 10 days or longer.

How should you use Polymyxin B sulfate, Neomycin sulfate, Hydrocortisone?

To help clear up your infection completely, use Polymyxin B sulfate, Neomycin sulfate, Hydrocortisone exactly as prescribed for the full time of treatment, even if your symptoms have disappeared.

Administer the eyedrops as follows:
1. Shake the dropper bottle well.
2. Wash your hands thoroughly.
3. Gently pull your lower eyelid down to form a pocket between your eye and eyelid.
4. Hold the bottle on the bridge of your nose or on your forehead.
5. Tilt your head back and squeeze the medication into your eye.
6. Do not touch the applicator tip to any surface, including your eye.
7. Close your eyes gently, and keep them closed for 1 to 2 minutes.
8. Do not rinse the dropper.
9. Wait 5 to 10 minutes before using any other eyedrops.

If you do not improve after 2 days, your doctor should re-evaluate your case.

Do not share Polymyxin B sulfate, Neomycin sulfate, Hydrocortisone with anyone else; you may spread the infection.

--If you miss a dose...

Apply it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule.

--Storage instructions...

Store at room temperature. Keep tightly closed and protect from freezing.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue using Cortisporin.

  • More common side effects may include:
    Cataract formation (results in blurred vision), delayed wound healing, increased eye pressure (with possible development of glaucoma and, infrequently, optic nerve damage), irritation when drops are instilled, local allergic reactions (itching, swelling, redness), other infections (particularly fungal infections of the cornea and bacterial eye infections), severe allergic reactions

Why should Polymyxin B sulfate, Neomycin sulfate, Hydrocortisone not be prescribed?

Cortisporin should not be used if you have certain viral or fungal diseases of the eye, including inflammation of the cornea caused by herpes simplex, chickenpox, or cowpox, or if you are sensitive to or have ever had an allergic reaction to any of its ingredients.

Special warnings about Polymyxin B sulfate, Neomycin sulfate, Hydrocortisone

Remember that steroids such as hydrocortisone may hide the existence of an infection or worsen an existing one.

If you are using Polymyxin B sulfate, Neomycin sulfate, Hydrocortisone for more than 10 days, your doctor should routinely check your eye pressure. If you already have high pressure within the eye (glaucoma), use Polymyxin B sulfate, Neomycin sulfate, Hydrocortisone cautiously.

Neomycin, one of the ingredients in Cortisporin, may cause an allergic reaction--usually itching, redness, and swelling--or failure to heal. If you develop any of these signs, stop using Cortisporin; the symptoms should quickly subside. If the condition persists or gets worse, or if a rash or allergic reaction develops, call your doctor immediately. You are more likely to be sensitive to neomycin if you are sensitive to the following antibiotics: kanamycin, paromomycin, streptomycin, and possibly gentamicin.

The use of steroids in the eye can prolong and worsen many viral infections of the eye, including herpes simplex. Use Polymyxin B sulfate, Neomycin sulfate, Hydrocortisone with extreme caution if you have this infection.

If you develop a sensitivity to Cortisporin, avoid other topical medications that contain neomycin.

Eye products that are not handled properly can become contaminated with bacteria that cause eye infections. If you use a contaminated product, you can seriously damage your eyes, even to the point of blindness.

Possible food and drug interactions when taking Polymyxin B sulfate, Neomycin sulfate, Hydrocortisone

No interactions have been reported.

Special information if you are pregnant or breastfeeding

Although the effects of Cortisporin during pregnancy have not been adequately studied, steroids should be used during pregnancy only if the benefits outweigh the dangers to the fetus. If you are pregnant or plan to become pregnant, inform your doctor immediately. Hydrocortisone, when taken orally, appears in breast milk. Since medication may be absorbed into the bloodstream when it is applied to the eye, your doctor may advise you to stop breastfeeding until your treatment with Cortisporin is finished.

Recommended dosage

ADULTS

The usual recommended dose is 1 or 2 drops in the affected eye every 3 or 4 hours, depending on the severity of the condition. Cortisporin may be used more often if necessary.

Overdosage

Any medication used in excess can have serious consequences. If you suspect an overdose of Cortisporin Ophthalmic Suspension, seek medical treatment immediately.

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