20 . September , 2018 - Thursday
Check todays hot topics or new products

Find a Drug: Advanced

Please Sign in or Register

All about: Porfimer

Big Image

Some commonly used brand names are:

In the U.S.—

  • Photofrin


  • Antineoplastic


Porfimer (POR-fi-mer) belongs to the group of medicines known as antineoplastics. It is used, together with a special laser light, to treat cancer of the esophagus (the part of the digestive tract that carries food to the stomach) and to treat a form of lung cancer.

This medicine is available only with your doctor's prescription, in the following dosage form:

  • Parenteral
  • Injection (U.S.)

Before Receiving This Medicine

In deciding to use a medicine, the risks of using the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For porfimer, the following should be considered:

Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to porfimer. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy—Porfimer has not been studied in humans. However, it has caused harm to the fetus in animals. It is best to use some kind of birth control while you are receiving porfimer. Tell your doctor right away if you think you have become pregnant while receiving this medicine.

Breast-feeding—It is not known whether porfimer passes into breast milk. However, because this medicine may cause serious side effects, breast-feeding is generally not recommended while you are receiving it.

Children—There is no specific information comparing use of porfimer in children with use in other age groups.

Older adults—Porfimer has been studied in elderly patients. It has not been shown to cause different side effects or problems in older people than it does in younger adults.

Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are being treated with porfimer, it is important that your health care professional know if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Other medical problems—The presence of other medical problems may affect the use of porfimer. Make sure you tell your doctor if you have any other medical problems, especially:

  • Porphyria

Proper Use of This Medicine

Treatment with porfimer and laser light occurs in three steps. First, the porfimer is injected into your body. Second, about 2 days later, a laser light is directed at the cancer. Then, about 2 or 3 days after the light is applied, your doctor will remove the cancer cells that have been destroyed.

Dosing—The dose of porfimer will be different for different patients. The dose that is used may depend on a number of things, including the patient's weight. If you have any questions about the proper dose of porfimer, ask your doctor.

  • For injection dosage form:
    • For treating cancer of the esophagus or lung cancer:
      • Adults—2 milligrams (mg) per kilogram (about 0.8 mg per pound) of body weight, injected into a vein.
      • Children—Use and dose must be determined by your doctor.

Precautions After Receiving This Medicine

For at least 30 days after you receive an injection of porfimer, your eyes will be extra sensitive to light, including sunlight, bright indoor lights, and vehicle headlights. Certain types of sunglasses can help protect your eyes during this time. Check with your doctor about which sunglasses to use .

For at least 30 days after you receive an injection of porfimer, your skin will be extra sensitive to sunlight and to very bright indoor lights, such as lamps with unshaded light bulbs and lights in dental offices or operating rooms. Do not expose your skin to direct sunlight or to bright indoor lights during this time . Sunscreens will not protect your skin from a severe reaction to light (blistering, burning, and swelling of the skin). However, exposure to normal amounts of indoor light (for example, daylight or light from lamps with shades) will help use up the porfimer remaining in your skin. Therefore, do not protect your skin from normal amounts of indoor light . If you have any questions about whether the light in your home is too bright, check with your doctor or nurse. Also, ask your doctor or nurse ahead of time about what you should do if a severe reaction to light occurs .

Thirty days after receiving an injection of porfimer, test a small portion of your skin by exposing it to sunlight for 10 minutes . (Do not test skin on your face.) If the exposed part of your skin does not become blistered, red, or swollen during the next 24 hours, you can slowly increase your exposure to sunlight and bright indoor lights. If a reaction does occur, wait another 2 weeks, then test your sensitivity to sunlight again.

Even after your skin and eyes are no longer sensitive to the lights in your home or the amount of sunlight in the area where you live, you may still be sensitive to brighter levels of light. If you travel to an area where the sunlight is stronger than at home, test yourself again before exposing your skin to the stronger light.

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Coughing, difficulty in swallowing, breathing problems, and problems caused by sensitivity to light have occurred in patients being treated for lung cancer as well as in patients being treated for cancer of the esophagus. Spitting blood has been reported only in patients being treated for lung cancer. The other side effects listed below have occurred only in patients being treated for cancer of the esophagus. The number and kinds of side effects that might occur depend on where in the esophagus the tumor is located and on the size of the tumor.

Check with your doctor immediately if any of the following side effects occur:

More common

Fast or irregular heartbeat; shortness of breath or troubled breathing; spitting blood

Less common

Abdominal or stomach pain (severe); chest pain; painful and/or difficult breathing

Also, check with your doctor as soon as possible if any of the following side effects occur:

More common

Abdominal or stomach pain (mild or moderate); bloody or cloudy urine; coughing; difficult, burning, or painful urination; difficulty in swallowing; dizziness (severe) or fainting; fever; frequent urge to urinate; swelling of face, feet, or lower legs; tightness in chest or wheezing; unusual tiredness or weakness; unusual weight gain; white patches inside the mouth

Less common

Chills; constipation (severe); nausea and vomiting (severe); swelling of the neck; yellow eyes or skin

This medicine may also cause the following side effects that your doctor will watch for:

More common

High blood pressure; low blood pressure

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

More common

Blistering, redness, or swelling of skin; constipation (mild); diarrhea; nausea and vomiting (mild or moderate); trouble in sleeping; weakness

Less common

Double vision or other changes in vision; eye pain when looking into bright light, including vehicle headlights

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

Developed: 04/08/1997
Revised: 07/02/1998

The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products.

Recent Drug Updates at DrugIndexOnline:

Calcium 600 Calcium 600
Some commonly used brand names are: In the U.S.— Alka-Mints 2 Amitone 2 Calcarb 600 2 Calci-Chew 2 Calciday 667 2 Calcilac 2 Calci-Mix 2 Calcionate 5 Calcium 600 2 Calglycine 2 Calphosan 9 Cal-Plus 2 Caltrate 600 2 Caltrate Jr 2 Chooz 2 Citracal 4 Citracal Liquitabs 4 Dicarbosil 2 Gencalc more...

Cholac Cholac
Some commonly used brand names are: In the U.S.— Agoral 35 Alophen 25 Alphamul 30 Alramucil Orange 7 Alramucil Regular 7 Bisac-Evac 25 Black-Draught 26 Black-Draught Lax-Senna 32 Carter's Little Pills 25 Cholac 14 Citroma 16 Citrucel Orange Flavor 3 Citrucel Sugar-Free Orange Flavor 3 Col more...

cyproheptadine cyproheptadine
Generic Name: cyproheptadine (sip row HEP ta deen) Brand Names: Periactin What is cyproheptadine? Cyproheptadine is an antihistamine. Cyproheptadine blocks the effects of the naturally occurring chemical histamine in your body. Cyproheptadine is used to treat sneezing; runny nose; itchin more...

lactulose lactulose
Generic Name: lactulose (LACK too lohss) Brand Names: Cephulac, Chronulac, Constulose, Duphalac, Enulose What is lactulose? Lactulose is a type of sugar. It is broken down into mild acids in the colon (the end part of the intestinal tract). These acids draw water into the colon and there more...

Lamisil Lamisil
Generic Name: terbinafine hydrochloride Dosage Form: Tablets T2005-69       Lamisil®       (terbinafine hydrochloride)             Tablets       Rx only Prescribin more...

Levobunolol Levobunolol
Pronouncation: (LEE-voe-BYOO-no-lahl) Class: Beta-adrenergic blocking agent, Ophthalmic Trade Names: AK-Beta - Solution 0.25% - Solution 0.5% Trade Names: Betagan Liquifilm - Solution 0.25% - Solution 0.5% Apo-Levobunolol (Canada) Betagan (Canada) Novo-Levobunolol (Canada) PMS-Levobunolol (Canada) more...

Nifurtimox Nifurtimox
Some commonly used brand names are: Lampit Another commonly used name is Bayer 2502 . *† Not commercially available in the U.S. and Canada. Category Antiprotozoal, systemic Description Nifurtimox (nye-FER-tim-oks) belongs to a group of medicines called antiprotozoals. It is used more...

Norpace Norpace
Generic name: Disopyramide phosphate Brand names: Norpace, Norpace CR Why is Norpace prescribed? Norpace is used to treat severe irregular heartbeat. It relaxes an overactive heart and improves the efficiency of the heart's pumping action. Most important fact about Norpace Do not stop taking N more...