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All about: Praziquantel

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Generic Name: Praziquantel (pray-zi-KWON-tel)
Brand Name: Biltricide

Praziquantel is used for:

Treating certain worm infections (eg, schistosoma, liver flukes).

Praziquantel is an anthelmintic agent. It works by killing sensitive worms.

Do NOT use Praziquantel if:

  • you are allergic to any ingredient in Praziquantel
  • you have certain worm infections of the eye (ocular cysticercosis)
  • you are breast-feeding
  • you are taking rifampin

Contact your doctor or health care provider right away if any of these apply to you.

Before using Praziquantel :

Some medical conditions may interact with Praziquantel . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have liver, kidney, or heart problems or worm infection of the brain (eg, cerebral cysticercosis)

Some MEDICINES MAY INTERACT with Praziquantel . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Anticonvulsants (eg, phenytoin, phenobarbital, carbamazepine), chloroquine, dexamethasone, or rifampin because the effectiveness of Praziquantel may be decreased
  • Azole antifungals (eg, ketoconazole), cimetidine, or erythromycin because actions and side effects of Praziquantel may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Praziquantel may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Praziquantel :

Use Praziquantel as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Praziquantel with a full glass of water during meals.
  • Swallow Praziquantel whole. Do not break, crush, or chew before swallowing.
  • Take your doses at least 4 hours apart but not more than 6 hours apart unless directed otherwise by your doctor.
  • If you miss a dose of Praziquantel , take it as soon as possible. If it less than 4 hours until your next dose, contact your doctor to see if you need to establish a new dosing schedule.

Ask your health care provider any questions you may have about how to use Praziquantel .

Important safety information:

  • Praziquantel may cause drowsiness or dizziness. Do not drive, operate machinery, or do anything else that could be dangerous on the day that you use Praziquantel and on the following day.
  • Use Praziquantel with caution in the ELDERLY because they may be more sensitive to its effects.
  • Use Praziquantel with extreme caution in CHILDREN younger than 4 years of age. Safety and effectiveness in this age group have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Praziquantel , discuss with your doctor the benefits and risks of using Praziquantel during pregnancy. Praziquantel is excreted in breast milk. Do not breast-feed while you are using Praziquantel and for 72 hours after you have stopped using Praziquantel .

Possible side effects of Praziquantel :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; general feeling of being unwell; headache; nausea; stomach upset.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody diarrhea; fever; seizures; severe or persistent vomiting; slow or irregular heartbeat.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Praziquantel :

Store Praziquantel below 86 degrees F (30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Praziquantel out of the reach of children and away from pets.

General information:

  • If you have any questions about Praziquantel , please talk with your doctor, pharmacist, or other health care provider.
  • Praziquantel is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Praziquantel . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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