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All about: Prednisone Concentrate

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Generic Name: Prednisone Oral Concentrate (PRED-ni-sone)
Brand Name: Generics only. No brands available.

Prednisone Concentrate is used for:

Treating severe allergies, arthritis, asthma, multiple sclerosis, and skin conditions. It may also be used for other conditions as determined by your doctor.

Prednisone Concentrate is a corticosteroid. It works by decreasing or preventing tissues from responding to inflammation. It also modifies the body's response to certain immune stimulation.

Do NOT use Prednisone Concentrate if:

  • you are allergic to any ingredient in Prednisone Concentrate
  • you have a systemic fungal infection
  • you are currently taking mifepristone or disulfiram

Contact your doctor or health care provider right away if any of these apply to you.

Before using Prednisone Concentrate:

Some medical conditions may interact with Prednisone Concentrate. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you are scheduled for a vaccination with a live virus vaccine (eg, smallpox)
  • if you have an underactive thyroid, liver or kidney problems, diabetes, or ulcerative colitis
  • if you have heart problems, esophagitis, gastritis, stomach obstruction or perforation, or an ulcer
  • if you have a history of mental problems, such as depression
  • if you have a herpes infection in your eye or any other type of infection (bacterial, fungal, or viral); have or recently had tuberculosis (TB) or tested positive for TB, measles, or chickenpox

Some MEDICINES MAY INTERACT with Prednisone Concentrate. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Barbiturates (eg, phenobarbital), carbamazepine, hydantoins (eg, phenytoin), or rifampin because the effectiveness of Prednisone Concentrate may be decreased
  • Clarithromycin, azole antifungals (eg, ketoconazole), steroidal contraceptives (eg, desogestrel), or troleandomycin because side effects, such as weakness, confusion, muscle aches, joint pain, or low blood sugar, may occur
  • Methotrexate or ritodrine because the actions and side effects of these medicines may be increased
  • Hydantoins (eg, phenytoin), mifepristone, or live vaccines because the effectiveness of these medicines may be decreased
  • Anticoagulants (eg, warfarin) or aspirin because the actions and side effects of these medicines may be increased or decreased
  • Certain cephalosporins (eg, cefotetan), disulfiram, fluorouracil, furazolidone, metronidazole and derivatives (eg, tinidazole), or sulfonylureas (eg, glipizide) because risk of side effects, such as flushing, headache, fast or irregular heartbeat, nausea, or vomiting, may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Prednisone Concentrate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Prednisone Concentrate:

Use Prednisone Concentrate as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Prednisone Concentrate by mouth with food.
  • Use the dropper that comes with Prednisone Concentrate to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • If you miss a dose of Prednisone Concentrate, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Prednisone Concentrate.

Important safety information:

  • Patients on long-term steroid therapy should carry an ID card at all times that says they are taking Prednisone Concentrate.
  • Prednisone Concentrate makes you more susceptible to illnesses, especially if you take it for an extended period of time. Prevent infection by avoiding contact with people who have colds or other infections. If you are exposed to chickenpox, measles, or TB while taking Prednisone Concentrate or within 12 months after stopping Prednisone Concentrate, call your doctor. Report any injuries or signs of an infection (fever, sore throat, pain during urination, or muscle aches) that occur during treatment and within 12 months after stopping Prednisone Concentrate. Your dose may need to be adjusted or you may need to start taking Prednisone Concentrate again.
  • Tell your doctor or dentist that you take Prednisone Concentrate before you receive any medical or dental care, emergency care, or surgery.
  • Long-term use may cause cataracts, glaucoma, and eye infections.
  • Prednisone Concentrate may cause an elevation in blood pressure, salt and water retention, and increased potassium loss. You may need to restrict the use of salt and take a calcium supplement.
  • Prednisone Concentrate can cause calcium loss and promote the development of osteoporosis. Take adequate calcium and vitamin D supplements.
  • If you are taking Prednisone Concentrate for a long period of time, do not suddenly stop taking it without checking with your doctor.
  • Do not receive a live vaccine, especially smallpox, while you are taking Prednisone Concentrate. Talk with your doctor before you receive any vaccine.
  • Diabetes patients - Prednisone Concentrate may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Lab tests may be performed while you use Prednisone Concentrate. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Infants and CHILDREN on long-term therapy must be closely monitored by a health care provider.
  • Corticosteroids may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they take Prednisone Concentrate.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Prednisone Concentrate while you are pregnant. Prednisone Concentrate is found in breast milk. If you are or will be breast-feeding while you use Prednisone Concentrate, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Prednisone Concentrate:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Difficulty sleeping; feeling of a whirling motion; increased appetite; increased sweating; indigestion; mood changes; nervousness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); appetite loss; black, tarry stools; changes in menstrual periods; convulsions; depression; diarrhea; dizziness; exaggerated sense of well-being; fever; general body discomfort; headache; increased pressure in the eye; joint or muscle pain; mood swings; muscle weakness; personality changes; prolonged sore throat, cold, or fever; puffing of the face; severe nausea or vomiting; swelling of feet or legs; unusual weight gain; vomiting material that looks like coffee grounds; weakness; weight loss.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Prednisone Concentrate:

Store Prednisone Concentrate at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Prednisone Concentrate out of the reach of children and away from pets.

General information:

  • If you have any questions about Prednisone Concentrate, please talk with your doctor, pharmacist, or other health care provider.
  • Prednisone Concentrate is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Prednisone Concentrate. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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