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All about: Prilosec OTC Delayed-Release Tablets

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Generic Name: Omeprazole Magnesium Delayed-Release Tablets (oh-MEP-ra-zole)
Brand Name: Prilosec OTC

Prilosec OTC Delayed-Release Tablets is used for:

Treating frequent (2 or more days a week) heartburn. It may also be used for other conditions as determined by your doctor.

Prilosec OTC Delayed-Release Tablets is a proton pump inhibitor. It works by decreasing the amount of acid produced in the stomach.

Do NOT use Prilosec OTC Delayed-Release Tablets if:

  • you are allergic to any ingredient in Prilosec OTC Delayed-Release Tablets
  • you have black or bloody stools, trouble or pain when swallowing, or if you are vomiting blood
  • you are taking an HIV protease inhibitor (eg, atazanavir)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Prilosec OTC Delayed-Release Tablets:

Some medical conditions may interact with Prilosec OTC Delayed-Release Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have liver problems or stomach or bowel cancer
  • if you have nausea or vomiting; stomach pain; heartburn with lightheadedness, sweating, or dizziness; chest or shoulder pain with shortness of breath; unusual sweating; pain spreading to arms, neck, or shoulders; or lightheadedness
  • if you have unexplained weight loss; frequent chest pain; or frequent wheezing, especially along with heartburn
  • if you have had heartburn for more than 3 months

Some MEDICINES MAY INTERACT with Prilosec OTC Delayed-Release Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Clarithromycin or voriconazole because they may increase the risk of Prilosec OTC Delayed-Release Tablets's side effects
  • Anticoagulants (eg, warfarin), benzodiazepines (eg, diazepam), cilostazol, cyclosporine, digoxin, disulfiram, phenytoin, or tacrolimus because the risk of their side effects may be increased by Prilosec OTC Delayed-Release Tablets
  • Ampicillins, azole antifungals (eg, ketoconazole), ginkgo biloba, HIV protease inhibitors (eg, atazanavir), or iron because their effectiveness may be decreased by Prilosec OTC Delayed-Release Tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if Prilosec OTC Delayed-Release Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Prilosec OTC Delayed-Release Tablets:

Use Prilosec OTC Delayed-Release Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Prilosec OTC Delayed-Release Tablets by mouth on an empty stomach before eating breakfast.
  • Take Prilosec OTC Delayed-Release Tablets with a full glass of water (8 oz/240 mL).
  • Swallow Prilosec OTC Delayed-Release Tablets whole. Do not break, crush, or chew before swallowing.
  • You may take antacids while you are using Prilosec OTC Delayed-Release Tablets if you are directed to do so by your doctor.
  • If you also take an imidazole antifungal (eg, ketoconazole), take it at least 2 hours before taking Prilosec OTC Delayed-Release Tablets.
  • If you are also take sucralfate, take Prilosec OTC Delayed-Release Tablets at least 30 minutes before taking sucralfate.
  • You may take a 14 day course of Prilosec OTC Delayed-Release Tablets once every 4 months. Do not take Prilosec OTC Delayed-Release Tablets for longer than 14 days or take more than 1 course every 4 months without first checking with your doctor.
  • If you miss a dose of Prilosec OTC Delayed-Release Tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Prilosec OTC Delayed-Release Tablets.

Important safety information:

  • Prilosec OTC Delayed-Release Tablets may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Prilosec OTC Delayed-Release Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Prilosec OTC Delayed-Release Tablets may take 1 to 4 days to reach its full effect. Do NOT take more than the recommended dose or use for longer than 14 days without checking with your doctor.
  • Check with your doctor if your heartburn does not get better or if it gets worse. Check with your doctor if you need to take Prilosec OTC Delayed-Release Tablets for more than 14 days or if you need to take more than 1 course of treatment every 4 months.
  • Contact your doctor if you have any symptoms of a bleeding ulcer, such as black, tarry stools or vomit that looks like coffee grounds; or if you experience throat pain, chest pain, severe stomach pain, or trouble swallowing.
  • Prilosec OTC Delayed-Release Tablets may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Prilosec OTC Delayed-Release Tablets.
  • Prilosec OTC Delayed-Release Tablets should be used with caution in Asian patients; the risk of side effects may be increased in these patients.
  • Prilosec OTC Delayed-Release Tablets should not be used in CHILDREN younger than 18 years old without first checking with their doctor; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Prilosec OTC Delayed-Release Tablets while you are pregnant. Prilosec OTC Delayed-Release Tablets is found in breast milk. Do not breast-feed while taking Prilosec OTC Delayed-Release Tablets.

Possible side effects of Prilosec OTC Delayed-Release Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; headache.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); chest pain; dark urine; fast or irregular heartbeat; fever, chills, or sore throat; red, swollen, blistered, or peeling skin; swelling of the hands, ankles, or feet; unusual bruising or bleeding; unusual tiredness; vision changes; yellowing of the eyes or skin.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include blurred vision; confusion; fast heartbeat; flushing; increased sweating; severe headache, drowsiness, or nausea; vomiting.

Proper storage of Prilosec OTC Delayed-Release Tablets:

Store Prilosec OTC Delayed-Release Tablets at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Prilosec OTC Delayed-Release Tablets out of the reach of children and away from pets.

General information:

  • If you have any questions about Prilosec OTC Delayed-Release Tablets, please talk with your doctor, pharmacist, or other health care provider.
  • Prilosec OTC Delayed-Release Tablets is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Prilosec OTC Delayed-Release Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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