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All about: Proloprim

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Generic Name: trimethoprim (trye METH oh prim)
Brand Names: Proloprim, Trimpex

What is Proloprim (trimethoprim)?

Trimethoprim is an antibiotic. It fights bacteria in your body.

Trimethoprim is used to treat urinary tract infections.

Trimethoprim may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Proloprim (trimethoprim)?

Take all of the trimethoprim that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated.

What should I discuss with my healthcare provider before taking Proloprim (trimethoprim)?

Before taking this medication, tell your doctor if you have

  • kidney disease,

  • liver disease, or

  • anemia.

You may not be able to take trimethoprim, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Trimethoprim is in the FDA pregnancy category C. This means that it is not known whether trimethoprim will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant. Trimethoprim passes into breast milk and may harm a nursing infant. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. Trimethoprim is not approved for use by children younger than 2 months of age.

How should I take Proloprim (trimethoprim)?

Take this drug exactly as directed by your physician. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. Take all of the trimethoprim that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated. Store trimethoprim at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the dose you missed and take only your next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a trimethoprim overdose include nausea, vomiting, dizziness, headache, and confusion.

What should I avoid while taking Proloprim (trimethoprim)?

There are no restrictions on food, beverages, or activities while you are taking trimethoprim unless your doctor directs otherwise.

Proloprim (trimethoprim) side effects

Stop taking trimethoprim and seek emergency medical attention or notify your doctor immediately if you experience any of the following serious side effects:
  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

  • unusual bleeding or bruising; or

  • sore throat or fever.

Other, less serious side effects may be more likely to occur. Continue to take your medication and talk to your doctor if you experience

  • nausea, vomiting, or decreased appetite;

  • swollen or sore tongue; or

  • a rash or itching.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Proloprim (trimethoprim)?

Trimethoprim may increase the effects of phenytoin (Dilantin) and lead to dangerous side effects. If you are taking phenytoin, notify your doctor of any unusual side effects during treatment with trimethoprim.

Drugs other than those listed here may also interact with trimethoprim. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Where can I get more information?

  • Your pharmacist has additional information about trimethoprim written for health professionals that you may read.

What does my medication look like?

Trimethoprim is available with a prescription under the brand names Trimpex and Proloprim. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

  • Trimpex 100 mg--white, scored tablets

  • Proloprim 100 mg--white, scored tablets

  • Proloprim 200 mg--yellow, scored tablets

  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 2.01. Revision Date: 9/28/04 2:38:05 PM.

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