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All about: Propofol

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Generic Name: Propofol (PROE-poe-fol)
Brand Name: Diprivan

Propofol is used for:

Starting or maintaining anesthesia during certain surgeries, tests, or procedures. It may also be used for other conditions as determined by your doctor.

Propofol is a general anesthetic. It is unknown exactly how Propofol works.

Do NOT use Propofol if:

  • you are allergic to any ingredient in Propofol
  • you are allergic to eggs, egg products, soybeans, or soy products

Contact your doctor or health care provider right away if any of these apply to you.

Before using Propofol :

Some medical conditions may interact with Propofol . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have inflammation of the pancreas, high lipid levels in the blood, or epilepsy

Some MEDICINES MAY INTERACT with Propofol . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Benzodiazepines (eg, alprazolam), narcotic pain relievers (eg, morphine), or other sedatives (eg, chloral hydrate) because they may increase the risk of Propofol 's side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Propofol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Propofol :

Use Propofol as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Propofol is usually administered as an injection at your doctor's office, hospital, or clinic.
  • If you miss a dose of Propofol , contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Propofol .

Important safety information:

  • Propofol may decrease mental alertness for some time after use. This effect may be worse if you drink alcohol or take certain medicines. Do not drive or perform other possibly unsafe tasks until you know how you react to it. Use caution signing legal documents.
  • Propofol may have benzyl alcohol in it. Do not use it in NEWBORNS or INFANTS. It may cause serious and sometimes fatal nervous system problems and other side effects.
  • Use Propofol with caution in the ELDERLY; they may be more sensitive to its effects.
  • Propofol should not be used to start anesthesia in CHILDREN younger than 3 years old. Propofol should not be used to maintain anesthesia in CHILDREN younger than 2 months old. Safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Propofol while you are pregnant. Propofol is found in breast milk. Do not breast-feed while taking Propofol .

Possible side effects of Propofol :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Change in mood or emotions; dizziness; drowsiness; lack of coordination.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); cough; feeling faint; itching; pain, redness, or swelling at the injection site; wheezing.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Propofol :

Propofol is usually handled and stored by a health care provider. Keep Propofol out of the reach of children and away from pets.

General information:

  • If you have any questions about Propofol , please talk with your doctor, pharmacist, or other health care provider.
  • Propofol is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Propofol . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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