16 . August , 2018 - Thursday
Check todays hot topics or new products

Find a Drug: Advanced

Please Sign in or Register

All about: Rabeprazole

Big Image

Some commonly used brand names are:

In the U.S.—

  • AcipHex

Not commercially available in Canada.

Category

  • Gastric acid pump inhibitor
  • Antiulcer agent

Description

Rabeprazole (ra-BE-pray-zole) is used to treat certain conditions in which there is too much acid in the stomach. It is used to treat duodenal ulcers and gastroesophageal reflux disease (GERD), a condition in which the acid in the stomach washes back up into the esophagus. Rabeprazole is also used to treat Zollinger-Ellison disease, a condition in which the stomach produces too much acid. Sometimes rabeprazole is used along with antibiotics to treat ulcers associated with infection caused by the H. pylori bacteria (germ).

Rabeprazole works by decreasing the amount of acid produced by the stomach.

This medicine is available only with your doctor's prescription.

  • Oral
  • Delayed-release tablet (U.S.)

Before Using This Medicine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For rabeprazole, the following should be considered:

Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to rabeprazole. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy—Studies have not been done in humans. However, studies in animals have not been shown that rabeprazole causes harm to the fetus.

Breast-feeding—Rabeprazole may pass into the breast milk. Since this medicine has been shown to cause a decrease in body weight gain in animal studies, it may be necessary for you to take another medicine or to stop breast-feeding during treatment. Be sure you discussed the risks and benefits of the medicine with your doctor.

Children—There is no specific information comparing the use of rabeprazole in children with use in other age groups.

Older adults—In studies done to date that have included older adults, rabeprazole did not cause different side effects or problems than it did in younger adults.

Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking rabeprazole, it is especially important that your health care professional know if you are taking any of the following:

  • Cyclosporine (e.g., Neoral)—Rabeprazole may increase the amount of cyclosporine in the blood.
  • Digoxin (e.g., Lanoxin)—Rabeprazole may increase the amount of digoxin in the blood.
  • Ketoconazole (e.g., Nizoral tablets)—Rabeprazole may decrease the amount of ketoconazole absorbed into the body.
  • Warfarin (e.g., Coumadin)—May cause serious unwanted effects including abnormal bleeding

Other medical problems—

  • Liver disease—May increase chance of side effects
  • Stomach infection—May make the condition worse

Proper Use of This Medicine

Swallow the tablet whole. Do not crush, chew, or split the tablet . Take this medicine for the full time of treatment, even if you begin to feel better . Also, keep your appointments with your doctor for check-ups so that your doctor will be better able to tell you when to stop taking this medicine.

Dosing—The dose of rabeprazole will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of rabeprazole. If your dose is different, do not change it unless your doctor tells you to do so.

The number of doses you take each day and the length of time you take the medicine depend on the medical problem for which you are taking rabeprazole

  • For oral dosage form (delayed-release tablet):
    • To treat gastroesophageal reflux disease (GERD):
      • Adults—20 mg once a day for 4 to 8 weeks.
      • Children up to 18 years of age—Use and dose must be determined by your doctor
    • To prevent gastroesophageal reflux disease (GERD):
      • Adults—20 mg once a day.
      • Children up to 18 years of age—Use and dose must be determined by your doctor
    • To treat duodenal ulcers:
      • Adults—20 mg once a day after the morning meal for up to 4 weeks.
      • Children up to 18 years of age—Use and dose must be determined by your doctor.
    • To treat duodenal ulcers related to infection with H. pylori
      • Adults—20 mg twice a day, plus amoxicillin 1000 mg (1 gram) twice a day plus clarithromycin 500 mg twice a day, all taken together before the morning and evening meals for seven days.
      • Children up to 18 years of age—Use and dose must be determined by your doctor.
    • To treat conditions in which the stomach produces too much acid:
      • Adults—At first, 60 mg once a day. Your doctor may increase your dose if needed.
      • Children up to 18 years of age—Use and dose must be determined by your doctor.

Missed dose—If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage—To store this medicine:

  • Keep out of the reach of children.
  • Store away from heat and direct light.
  • Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
  • Do not keep outdated medicine or medicine no longer needed. Ask your health care professional how you should dispose of any medicine you do not use. Be sure that any discarded medicine is out of the reach of children.

Precautions While Using This Medicine

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects. If your condition does not improve, or it becomes worse, discuss this with your doctor.

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Rare

Breathing interruptions; bloody urine; convulsions (seizures); chills, fever, or sore throat; continuing ulcers or sores in mouth; unusual bleeding or bruising; unusual tiredness or weakness; yellow eyes or skin

Incidence not known

Blistering, peeling, loosening of skin; change in consciousness; clay-colored stools; cloudy urine; confusion about identity, place, person, and time; continuing nausea or vomiting; cough; dark urine; difficult breathing; difficulty swallowing; fast heartbeat; greatly decreased frequency of urination or amount of urine; hallucinations; hives, itching, puffiness or swelling of the eyelids or around the eyes, face, lips or tongue; holding false beliefs that cannot be changed by fact; increase in frequency of seizures; itching; joint or muscle pain; large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, sex organs; loss of appetite; loss of consciousness; muscle cramps or spasms; muscle pain or stiffness; no blood pressure; no breathing; no pulse; red, irritated eyes; red skin lesions, often with a purple center; shortness of breath; skin blisters; skin rash; sores, ulcers, or white spots in mouth or on lips; swelling of face; swelling of feet or lower legs; tightness in chest; tiredness and weakness; unusual excitement, nervousness or restlessness; wheezing

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

More common

Headache

Less common or rare

Constipation; diarrhea ; dizziness; feeling weak; gas; heartburn; itchy skin; nausea and vomiting; numbness, tingling, pain, or weakness in hands or feet; sleepiness; stomach pain

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

Developed: 12/02/1999
Revised: 07/13/2005

The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products.

Recent Drug Updates at DrugIndexOnline:





Alemtuzumab Alemtuzumab
Generic Name: Alemtuzumab (al-em-TUE-zue-mab) Brand Name: CampathSerious infections, blood disorders, and infusion reactions have occurred from the use of Alemtuzumab . You will be closely monitored during the infusion and it may be necessary to stop treatment if an infusion reaction occurs. Not more...

Clarinex Reditab Disintegrating Tablets Clarinex Reditab Disintegrating Tablets
Generic Name: Desloratadine Orally Disintegrating Tablets (des-lor-AT-a-deen) Brand Name: Clarinex ReditabClarinex Reditab Disintegrating Tablets is used for:Treating allergies and chronic hives. It may also be used for other conditions as determined by your doctor. Clarinex Reditab Disintegrati more...

dextromethorphan and promethazine dextromethorphan and promethazine
Generic Name: dextromethorphan and promethazine (dex troe me THOR fan and pro METH a zeen) Brand Names: Promethazine with Dextromethorphan, Promethazine with DM What is dextromethorphan and promethazine? Dextromethorphan is a cough suppressant. It affects the signals in the brain that tr more...

Hycamtin Hycamtin
Generic Name: topotecan hydrochloride Dosage Form: Injection Warning Hycamtin (topotecan hydrochloride) for Injection should be administered under the supervision of a physician experienced in the use of cancer chemotherapeutic agents. Appropriate management of complications is possible only whe more...

Novahistine DH Liquid Novahistine DH Liquid
Some commonly used brand names are: In the U.S.— Alka-Seltzer Plus Cold and Cough 21 Alka-Seltzer Plus Cold and Cough Medicine Liqui-Gels 34 Alka-Seltzer Plus Night-Time Cold Liqui-Gels 35 Ami-Tex LA 69 Anatuss LA 70 Benylin Expectorant 54 Bromfed-DM 17 Broncholate 68 Carbinoxamine Compou more...

Novolog Injection Novolog Injection
Generic Name: insulin aspart Dosage Form: Injection Novolog Description Novolog Mix 70/30 (70% insulin aspart protamine suspension and 30% insulin aspart injection, [rDNA origin]) is a human insulin analog suspension containing 70% insulin aspart protamine crystals and 30% soluble insulin aspart. more...

Paraldehyde Paraldehyde
Some commonly used brand names are: In the U.S.— Paral Generic name product may be available in the U.S. and Canada. Category Anticonvulsant Description Paraldehyde (par-AL-de-hyde) is used to treat certain convulsive disorders. It also has been used in the treatment of alcoholis more...

PCE PCE
Generic Name: erythromycin particles in tablets Dosage Form: Dispertab tablets To reduce the development of drug-resistant bacteria and maintain the effectiveness of PCE and other antibacterial drugs, PCE should be used only to treat or prevent infections that are proven or strongly suspected to more...