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All about: Avage Cream

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Generic Name: Tazarotene Facial Wrinkle Cream (taz-AR-oh-teen)
Brand Name: Avage

Avage Cream is used for:

Reducing the appearance of fine wrinkles, certain dark and light spots, and certain lesions on the face. Avage Cream is used with a total skin care and sunlight avoidance program. It may also be used for other conditions as determined by your doctor.

Avage Cream is a retinoid. Exactly how Avage Cream works is unknown.

Do NOT use Avage Cream if:

  • you are allergic to any ingredient in Avage Cream
  • you are pregnant

Contact your doctor or health care provider right away if any of these apply to you.

Before using Avage Cream:

Some medical conditions may interact with Avage Cream. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you are of childbearing age
  • if you have eczema, sunburn, or high blood lipid levels, or if you are unusually sensitive to sunlight

Some MEDICINES MAY INTERACT with Avage Cream. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Fluoroquinolones (eg, levofloxacin), phenothiazines (eg, chlorpromazine), sulfonamides (eg, glipizide, sulfamethoxazole), tetracyclines (eg, doxycycline), thiazide diuretics (eg, hydrochlorothiazide), or vitamin A because the risk of sunburn may be increased by Avage Cream

This may not be a complete list of all interactions that may occur. Ask your health care provider if Avage Cream may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Avage Cream:

Use Avage Cream as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Avage Cream. Talk to your pharmacist if you have questions about this information.
  • Avage Cream is for topical use only.
  • Before applying Avage Cream, gently wash your face with a mild soap. Make sure you remove all makeup before applying Avage Cream. Wait 20 to 30 minutes to make sure your skin is dry before applying Avage Cream.
  • Apply a small pea-sized amount of Avage Cream to the affected areas on your face once a day in the evening. This should be enough to lightly cover the entire face.
  • In the morning, apply a moisturizing sunscreen with SPF 15 or greater.
  • Other creams or lotions can be applied before or after using Avage Cream. Make sure that any other product applied is absorbed into the skin and completely dry before applying Avage Cream.
  • Wash your hands immediately after using Avage Cream.
  • If you miss a dose of Avage Cream, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Avage Cream.

Important safety information:

  • Avoid getting Avage Cream in your eyes, nose, mouth, vagina, or on healthy skin. If you get Avage Cream in your eyes, rinse thoroughly with water.
  • Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • Follow your doctor's advice for routine skin care and for makeup, moisturizer, and sunscreen use.
  • Avoid using other topical medications or cosmetics that have a strong drying effect. If you have dry skin from using these products, allow your skin to "rest" before using Avage Cream.
  • Do not use Avage Cream on skin with eczema, certain types of skin lesions (eg, lentigo maligna), or for any condition other than that for which it was prescribed.
  • If you have a sunburn, do not use Avage Cream on the sunburned skin until it has fully healed.
  • Weather extremes, such as windy or cold weather, may irritate your skin more while you are using Avage Cream.
  • If you are using a cream or lotion to soften or moisten your skin, do not apply Avage Cream until the first cream or lotion has been absorbed into your skin (at least 1 hour).
  • Avage Cream may cause harm if it is swallowed. If you may have taken it by mouth, contact your poison control center or emergency room right away.
  • Wear clothes that protect your skin from the sun and use nonprescription creams to help keep your skin soft.
  • Avoid electrolysis, hair depilatories, waxes, and other products or processes that may dry or irritate your skin.
  • Avage Cream may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Avage Cream. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Women of childbearing potential should use effective birth control methods (eg, condoms, birth control pills, diaphragms) while using Avage Cream. You should have a negative pregnancy test 2 weeks before starting Avage Cream. Contact your health care provider at once if you become pregnant while using Avage Cream.
  • Avage Cream should be used with extreme caution in CHILDREN younger than 17 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Do not use Avage Cream if you are pregnant. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if Avage Cream is found in breast milk. Do not breast-feed while taking Avage Cream.

Possible side effects of Avage Cream:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Burning; dry skin; irritation; itching; peeling; redness; scaling; skin inflammation; skin pain; stinging.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe or prolonged itching, burning, redness, or peeling; sunburn; swelling of the skin, hands, or feet; swelling or cracking around the mouth; worsening of psoriasis.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include severe redness, peeling, or discomfort. Avage Cream may be harmful if swallowed.

Proper storage of Avage Cream:

Store Avage Cream at 77 degrees F (25 degrees C). Brief storage at temperatures between 23 and 86 degrees F (-5 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Avage Cream out of the reach of children and away from pets.

General information:

  • If you have any questions about Avage Cream, please talk with your doctor, pharmacist, or other health care provider.
  • Avage Cream is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Avage Cream. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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