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All about: Ultiva

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Generic Name: Remifentanil (rem-i-FEN-ta-nil)
Brand Name: Ultiva

Ultiva is used for:

Preventing and treating pain during and after procedures and surgery.

Ultiva is a narcotic pain reliever. It works by dulling the pain perception center in the brain.

Do NOT use Ultiva if:

  • you are allergic to any ingredient in Ultiva or to similar medicines (eg, fentanyl)
  • you are taking sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Ultiva :

Some medical conditions may interact with Ultiva . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have heart or breathing problems
  • if you have a history of substance abuse or dependence problems

Some MEDICINES MAY INTERACT with Ultiva . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Alcohol, amiodarone, benzodiazepines (eg, alprazolam), cimetidine, or sodium oxybate (GHB) because the side effects of Ultiva may be increased
  • Naltrexone because the effectiveness of Ultiva may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Ultiva may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Ultiva :

Use Ultiva as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Ultiva is usually administered as an injection at your doctor's office, hospital, or clinic. Ask your doctor or pharmacist any questions you may have about Ultiva .
  • If you miss a dose of Ultiva , contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Ultiva .

Important safety information:

  • Ultiva may cause dizziness or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Ultiva . Using Ultiva alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking Ultiva . Ultiva will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
  • Use Ultiva with caution in the ELDERLY because they may be more sensitive to its effects.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Ultiva during pregnancy. It is unknown if Ultiva is excreted in breast milk. If you are or will be breast-feeding while you are using Ultiva , check with your doctor or pharmacist to discuss the risks to your baby.

When used for long periods of time or at high doses, Ultiva may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Ultiva stops working well. Do not take more then prescribed.

When used for long periods of time or at high doses, some people develop a need to continue taking Ultiva . This is known as DEPENDENCE or addiction.

If you suddenly stop taking Ultiva , you may experience WITHDRAWAL symptoms, including anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea; vomiting; pain; rigid muscles; rapid heartbeat; seeing, hearing, or feeling things that are not there; shivering or tremors; sweating; and trouble sleeping.

Possible side effects of Ultiva :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Changes in vision; chills; dizziness; drowsiness; fever; headache; itching; nausea; shivering; sweating; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fast or slow heartbeat; interrupted breathing; lightheadedness; muscle tightness; pain, redness, or swelling at the injection site; seizures.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include difficulty breathing; dizziness; lightheadedness; seizures; slow heartbeat; tightening of muscles in the chest.

Proper storage of Ultiva :

Ultiva is usually handled and stored by a health care provider. If you are using Ultiva at home, store Ultiva as directed by your pharmacist or health care provider. Keep Ultiva , as well as needles and syringes, out of the reach of children and away from pets.

General information:

  • If you have any questions about Ultiva , please talk with your doctor, pharmacist, or other health care provider.
  • Ultiva is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Ultiva . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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