24 . September , 2018 - Monday
Check todays hot topics or new products

Find a Drug: Advanced

Please Sign in or Register

All about: Water for Injection

Big Image
Generic Name: Sterile Water for Injection, USP
Dosage Form: Injection

Water for Injection Description

Sterile Water for Injection, USP, is sterile, nonpyrogenic, distilled water in a single dose container for intravenous administration after addition of a suitable solute. It may also be used as a dispensing container for diluent use. No antimicrobial or other substance has been added. The pH is 5.5 (5.0 to 7.0). The osmolarity is 0.

The VIAFLEX plastic container is fabricated from a specially formulated polyvinyl chloride (PL 146 Plastic). The amount of water that can permeate from inside the container into the overwrap is insufficient to affect the solution significantly. Solutions in contact with the plastic container may leach out certain chemical components from the plastic in very small amounts; however, biological testing was supportive of the safety of the plastic container materials.

Water for Injection - Clinical Pharmacology

Sterile Water for Injection, USP is used for fluid replacement only after suitable additives are introduced to approximate isotonicity and to serve as a vehicle for suitable medications.

Indications and Usage for Water for Injection

Sterile Water for Injection, USP is indicated in the aseptic preparation of parenteral solutions.

Contraindications

Sterile Water for Injection, USP is a hemolytic agent due to its hypotonicity. Therefore, it is contraindicated for intravenous administration without additives.

Warnings

Do not use for intravenous injection unless adjusted to approximate isotonicity with a suitable solute.

Precautions

Do not administer unless solution is clear and seal is intact.

Adverse Reactions

The administration of a suitable admixture of prescribed additives may be associated with adverse reactions because of the solution or the technique of administration including febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation, and hypervolemia.

If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures, and save the remainder of the fluid for examination if deemed necessary.

Water for Injection Dosage and Administration

Following suitable admixture of prescribed additives, the dosage is usually dependent upon the age, weight and clinical condition of the patient as well as laboratory determinations. See directions accompanying additive drug.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit.

Injections in VIAFLEX plastic containers are intended for intravenous administration using sterile equipment.

Additives may be incompatible. Complete information is not available. Those additives known to be incompatible should not be used. Consult with pharmacist, if available. If, in the informed judgment of the physician, it is deemed advisable to introduce additives, use aseptic technique. Do not store an unused portion of Sterile Water for Injection, USP. Mix thoroughly when additives have been introduced. Do not store solutions containing additives.

How is Water for Injection Supplied

Sterile Water for Injection, USP is supplied in VIAFLEX plastic containers as follows:

1000 mL 2B0304 NDC 0338-0013-04

Exposure of pharmaceutical products to heat should be minimized. Avoid excessive heat. It is recommended the product be stored at room temperature (25°C); brief exposure up to 40°C does not adversely affect the product.

DIRECTIONS FOR USE OF VIAFLEX PLASTIC CONTAINER

Warning: Do not use plastic containers in series connections. Such use could result in air embolism due to residual air being drawn from the primary container before administration of the fluid from the secondary container is completed.

To Open

Tear overwrap down side at slit and remove solution container. Some opacity of the plastic due to moisture absorption during the sterilization process may be observed. This is normal and does not affect the solution quality or safety. The opacity will diminish gradually. Check for minute leaks by squeezing inner bag firmly. If leaks are found, discard solution as sterility may be impaired. See following directions.

Preparation for Administration After Rendering Isotonic

1. Suspend container from eyelet support.

2. Remove plastic protector from outlet port at bottom of container.

3. Attach administration set. Refer to complete directions accompanying set.

Warning: Additives may be incompatible.

To add medication before administration

1. Prepare medication site.

2. Using syringe with 19 to 22 gauge needle, puncture resealable medication port and inject.

3. Mix solution and medication thoroughly. For high density medication such as potassium chloride, squeeze ports while ports are upright and mix thoroughly.

To add medication during administration

1. Close clamp on the set.

2. Prepare medication site.

3. Using syringe with 19 to 22 gauge needle, puncture resealable medication port and inject.

4. Remove container from IV pole and/or turn to an upright position.

5. Evacuate both ports by squeezing them while container is in the upright position.

6. Mix solution and medication thoroughly.

7. Return container to in use position and continue administration.

Baxter Healthcare Corporation

Deerfield, IL 60015 USA

7-19-31-347 Rev. September 2002

BAXTER, VIAFLEX, and PL 146 are trademarks of Baxter International Inc.


Sterile Water (Water)
PRODUCT INFO
Product Code 0338-0013 Dosage Form INJECTION, SOLUTION
Route Of Administration INTRAVENOUS DEA Schedule
INGREDIENTS
Name (Active Moiety) Type Strength
Water (water) Active 100 MILLILITER  In 100 MILLILITER
IMPRINT INFORMATION
Characteristic Appearance Characteristic Appearance
Color Score
Shape Symbol
Imprint Code Coating
Size
PACKAGING
# NDC Package Description Multilevel Packaging
1 0338-0013-04 1000 MILLILITER In 1 BAG None

Revised: 09/2006

Recent Drug Updates at DrugIndexOnline:





Acamprosate Acamprosate
Generic Name: Acamprosate (a-kam-PROE-sate) Brand Name: CampralAcamprosate is used for:Treating alcohol addiction by helping certain patients to avoid alcohol. Acamprosate is used in combination with a treatment program that includes social support. Acamprosate is an anti-alcohol agent. It is more...

Catapres-TTS Catapres-TTS
Generic Name: clonidine Dosage Form: Transdermal therapeutic system Transdermal Therapeutic System Programmed delivery in vivo of 0.1, 0.2, or 0.3 mg clonidine per day, for one week. Prescribing Information DESCRIPTION Catapres-TTS is a transdermal system providing continuous systemic delivery o more...

Condylox Gel Condylox Gel
Generic Name: Podofilox Gel (po-do-FIL-ox) Brand Name: CondyloxCondylox Gel is used for:Treating external genital warts and warts around the anus. Condylox Gel is an antimitotic. Exactly how Condylox Gel works is unknown. Do NOT use Condylox Gel if:you are allergic to any ingredient in Condylox more...

Cordran Topical Cordran Topical
Some commonly used brand names are: In the U.S.— Alphatrex 3 Aristocort 20 Aristocort A 20 Betatrex 3 Beta-Val 3 Bio-Syn 9 Cordran 11 Cordran SP 11 Cormax 4 Cutivate 12 Cyclocort 1 Delta-Tritex 20 Dermabet 3 Dermatop 19 Diprolene 3 Diprolene AF 3 Diprosone 3 Elocon 18 Florone 7 Florone E more...

Myobloc Parenteral-Local Myobloc Parenteral-Local
Some commonly used brand names are: In the U.S.— Myobloc Category Neuromuscular blocking agent Description Botulinum toxin type B (BOT-yoo-lye-num ) is used to treat abnormal head position and neck pain that is a result of cervical dystonia. Botulinum toxin type B is injected int more...

pemetrexed pemetrexed
Generic Name: pemetrexed (pem e TREX ed) Brand Names: Alimta What is pemetrexed? Pemetrexed is a cancer medication that interferes with the growth of cancer cells and slows their growth and spread in the body. Pemetrexed is used to treat mesothelioma, a form of lung cancer associated wit more...

Pen Vee K Pen Vee K
Some commonly used brand names are: In the U.S.— Amoxil 1 Bactocill 11 Beepen-VK 13 Betapen-VK 13 Bicillin L-A 12 Cloxapen 5 Crysticillin 300 A.S. 12 Dynapen 6 Dycill 6 Geocillin 4 Geopen 4 Ledercillin VK 13 Mezlin 9 Nafcil 10 Nallpen 10 Omnipen 2 Omnipen-N 2 Pathocil 6 Pentids 12 Pen Vee more...

Pentazocine Pentazocine
Pronouncation: (pen-TAZ-oh-seen) Class: Opioid agonist-antagonist analgesic Trade Names: Talacen - Tablets 25 mg pentazocine (as HCl)/650 mg acetaminophen Trade Names: Talwin - Injection 30 mg/mL (as lactate) Trade Names: Talwin Compound - Tablets 12.5 mg pentazocine (as HCl)/325 mg aspirin Trade N more...