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All about: Brinzolamide Drops

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Generic Name: Brinzolamide Eye Drops (brin-ZOE-lah-mide)
Brand Name: Azopt

Brinzolamide Drops is used for:

Treating elevated pressure inside the eye in patients with open-angle glaucoma or ocular hypertension.

Brinzolamide Drops is a carbonic anhydrase inhibitor. It works by decreasing the production of fluid inside the eye, thereby lowering pressure within the eye.

Do NOT use Brinzolamide Drops if:

  • you are allergic to any ingredient in Brinzolamide Drops

Contact your doctor or health care provider right away if this applies to you.

Before using Brinzolamide Drops:

Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have liver or kidney disease
  • if you wear contact lenses
  • if you have had a severe allergic reaction (eg, a severe rash, hives, breathing difficulties, dizziness) to any other sulfonamide medicine, such as acetazolamide, celecoxib, certain diuretics (eg, hydrochlorothiazide), glyburide, probenecid, sulfamethoxazole, valdecoxib, or zonisamide

Some MEDICINES MAY INTERACT with Brinzolamide Drops. Because little, if any, of Brinzolamide Drops is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Brinzolamide Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Brinzolamide Drops:

Use this medicine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Shake well before each use.
  • To use Brinzolamide Drops in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eyelid for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
  • To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.
  • If you are using another medicine for your eye, use the medicines at least 10 minutes apart.
  • Remove soft contact lenses before you use Brinzolamide Drops; lenses may be placed back in the eyes 15 minutes after use of Brinzolamide Drops.
  • If you miss a dose of Brinzolamide Drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Brinzolamide Drops.

Important safety information:

  • Brinzolamide Drops may cause blurred vision. Use Brinzolamide Drops with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • If you suffer an eye injury, contact your doctor before using any more of Brinzolamide Drops.
  • Brief stinging or burning of the eye may occur after use. This is normal. Contact your doctor if symptoms continue or worsen.
  • Brinzolamide Drops should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Brinzolamide Drops while you are pregnant. It is not known if Brinzolamide Drops is found in breast milk. Do not breast-feed while taking Brinzolamide Drops.

Possible side effects of Brinzolamide Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Bitter, sour, or unusual taste; blurred vision; discomfort, tearing, or dryness of the eyes when first applied; dry eyes; eye discharge; foreign body sensation in the eye; headache; inflammation of the eyelids; runny nose; swelling of the cornea.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); eye pain or itching; irritated eyelids.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Brinzolamide Drops may be harmful if swallowed.

Proper storage of Brinzolamide Drops:

Store Brinzolamide Drops at room temperature between 68 and 77 degrees F (20 and 25 degrees C). Store in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Brinzolamide Drops out of the reach of children and away from pets.

General information:

  • If you have any questions about Brinzolamide Drops, please talk with your doctor, pharmacist, or other health care provider.
  • Brinzolamide Drops is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Brinzolamide Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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