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All about: Cabergoline

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Generic Name: Cabergoline (ka-BER-goe-leen)
Brand Name: Dostinex

Cabergoline is used for:

Treating disorders associated with high levels of the hormone prolactin, either due to tumors in the pituitary gland or to unknown causes. It may also be used for other conditions as determined by your doctor.

Cabergoline is a dopamine receptor agonist. It works by blocking prolactin secretion from the pituitary gland.

Do NOT use Cabergoline if:

  • you are allergic to any ingredient in Cabergoline or to ergot derivatives (eg, ergotamine)
  • you have uncontrolled high blood pressure
  • you are taking a butyrophenone (eg, haloperidol), metoclopramide, a phenothiazine (eg, chlorpromazine), or a thioxanthene (eg, thiothixene)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Cabergoline :

Some medical conditions may interact with Cabergoline . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have liver problems or high blood pressure, or if you take medicine that may lower your blood pressure
  • if you have high blood pressure or convulsions caused by pregnancy
  • if you have a history of certain lung or heart valve problems (eg, pleural effusion, pulmonary fibrosis)

Some MEDICINES MAY INTERACT with Cabergoline . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Butyrophenones (eg, haloperidol), metoclopramide, phenothiazines (eg, chlorpromazine), or thioxanthenes (eg, thiothixene) because they may decrease Cabergoline 's effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Cabergoline may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Cabergoline :

Use Cabergoline as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Cabergoline by mouth with or without food.
  • It may be helpful to mark on a calendar which days you are supposed to take Cabergoline .
  • If you miss a dose of Cabergoline , contact your doctor right away.

Ask your health care provider any questions you may have about how to use Cabergoline .

Important safety information:

  • Cabergoline may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Cabergoline with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Cabergoline may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
  • If you suspect that you may be pregnant, contact your doctor so that a pregnancy test can be arranged.
  • Cabergoline should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Cabergoline while you are pregnant. It is not known if Cabergoline is found in breast milk. Do not breast-feed while taking Cabergoline .

Possible side effects of Cabergoline :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness; headache; indigestion; nausea; tiredness or weakness; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); behavior changes (eg, aggression); chest pain; confusion; cough; depression; fainting; hallucinations; irregular heartbeat; mood or mental changes; shortness of breath; swelling of hands or feet; vision disturbances.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include fainting; hallucinations; nasal congestion.

Proper storage of Cabergoline :

Store Cabergoline at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep this medicine out of the reach of children and away from pets.

General information:

  • If you have any questions about Cabergoline , please talk with your doctor, pharmacist, or other health care provider.
  • Cabergoline is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Cabergoline . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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