22 . October , 2018 - Monday
Check todays hot topics or new products

Find a Drug: Advanced

Please Sign in or Register

All about: Carbidopa

Big Image
Generic Name: Carbidopa (kar-bi-DOE-pa)
Brand Name: Lodosyn

Carbidopa is used for:

Treating symptoms associated with Parkinson disease and parkinsonism-like symptoms caused by other conditions. It is used in combination with another medicine called levodopa. It may also be used for other conditions as determined by your doctor.

Carbidopa is an antiparkinson agent. It works by helping levodopa to reach the brain.

Do NOT use Carbidopa if:

  • you are allergic to any ingredient in Carbidopa
  • you have narrow-angle glaucoma, undiagnosed skin growths, skin cancer, or a history of skin cancer
  • you have taken a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Carbidopa :

Some medical conditions may interact with Carbidopa . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have an irregular heartbeat, heart disease, ulcer, seizures, blood pressure problems, asthma, lung problems, liver or kidney problems, blood or hormone problems, stomach or intestinal bleeding, glaucoma, or a history of heart attack, mental or mood problems, or suicidal thoughts or attempts

Some MEDICINES MAY INTERACT with Carbidopa . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Butyrophenones, (eg, haloperidol), isoniazid, papaverine, phenothiazines (eg, chlorpromazine), or risperidone because the effectiveness of Carbidopa may be decreased
  • MAO inhibitors (eg, phenelzine) because risk of severe high blood pressure may be increased
  • Tricyclic antidepressants (eg, amitriptyline) because risk of high blood pressure or unusual muscle movements may be increased
  • Metoclopramide because side effects may occur
  • Blood pressure medicines or selegiline because risk of severe dizziness on standing may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Carbidopa may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Carbidopa :

Use this medicine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Carbidopa on an empty stomach at least 1 hour before or 2 hours after eating.
  • Carefully follow the dosing schedule given to you by your health care provider. It may take several weeks to a few months to notice benefit from use because the dose is carefully adjusted over time.
  • If you are also taking iron salts (eg, ferrous sulfate), separate the administration of these medicines by at least 2 hours.
  • Take Carbidopa regularly to receive the most benefit from it. Taking Carbidopa at the same times each day will help you to remember to take it.
  • Continue taking Carbidopa even if you feel better. Do not miss any doses.
  • If you have been taking levodopa, do not start taking Carbidopa until at least 12 hours after your final dose of levodopa.
  • If you miss a dose of Carbidopa , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Carbidopa .

Important safety information:

  • Carbidopa may cause drowsiness, dizziness, or lightheadedness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Carbidopa . Using Carbidopa alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
  • Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking Carbidopa . Carbidopa will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
  • Alcohol, hot weather, exercise, and fever may increase the risk for drowsiness, dizziness, and lightheadedness. To prevent these effects, sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of dizziness, lightheadedness, or weakness.
  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Carbidopa .
  • Neuroleptic malignant syndrome (NMS) is a potentially deadly syndrome associated with Carbidopa . Symptoms may include: increased body heat; muscle rigidness; altered mental abilities, including lack of response to your surroundings; irregular or fast heartbeat; sweating. Contact your doctor at once if any of these symptoms occur.
  • Do not suddenly stop taking Carbidopa . Some conditions may become worse when Carbidopa is suddenly stopped. Your dose may need to be slowly lowered by your doctor to avoid side effects.
  • Gradually increase physical activity as your symptoms improve.
  • A dark color (red, brown, or black) may appear in your saliva, urine, or sweat after taking Carbidopa . This is not harmful.
  • The effects of Carbidopa might start to wear off between doses. Talk with your doctor if Carbidopa stops working well or if your condition worsens.
  • Diabetes patients - Carbidopa may interfere with urine tests for ketones and cause inaccurate test results. Check with your doctor before you adjust your dose of your diabetes medicine or change your diet.
  • Carbidopa may affect certain lab test results. Make sure laboratory personnel and your doctors know you use Carbidopa .
  • LAB TESTS, such as complete blood cell counts and heart, kidney, and liver function tests, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Carbidopa with caution in ELDERLY patients because they may be more sensitive to its effects.
  • Carbidopa is not recommended for use in CHILDREN younger than 18 years of age. Safety and effectiveness in this age group have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Carbidopa during pregnancy. It is unknown if Carbidopa is excreted in breast milk. Do not breast-feed if you are taking Carbidopa .

Possible side effects of Carbidopa :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Confusion; constipation; diarrhea; dizziness; drowsiness; dry mouth; headache; loss of appetite; nausea; taste changes; trouble sleeping; upset stomach; urinary tract infection; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood in vomit; chest pain; confusion; depression; fast or irregular heartbeat; fever; hallucinations; increased sweating; mental or mood changes; muscle pain or unusual stiffness; severe abdominal pain; severe lightheadedness or fainting; sore throat; thoughts of suicide; unusual bruising or bleeding; unusual or painful movements or spasms of the face, eyelids, mouth, tongue, arms, hands, or legs; vision changes (blurred/double vision); yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Carbidopa :

Store Carbidopa at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Carbidopa out of the reach of children and away from pets.

General information:

  • If you have any questions about Carbidopa , please talk with your doctor, pharmacist, or other health care provider.
  • Carbidopa is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Carbidopa . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

Recent Drug Updates at DrugIndexOnline:





Auranofin Auranofin
Generic Name: Auranofin (or-RAIN-oh-fin) Brand Name: RidauraAuranofin contains gold, which can build up in the blood and become toxic. Report any symptom suggesting toxicity (rash, mouth sores, persistent diarrhea, indigestion, metallic taste, unusual bleeding or bruising, itching, blood in the more...

E-Pilo-1 E-Pilo-1
Generic Name: epinephrine and pilocarpine ophthalmic (ep ih NEF rin and pie low CAR peen) Brand Names: E-Pilo-1, E-Pilo-2, E-Pilo-4, E-Pilo-6, P1E1, P2E1, P3E1, P4E1, P6E1 What is E-Pilo-1 (epinephrine and pilocarpine ophthalmic)? Epinephrine ophthalmic reduces congestion in the eye by more...

Equetro Equetro
Some commonly used brand names are: In the U.S.— Atretol Carbatrol Epitol Equetro Tegretol Tegretol-XR In Canada— Apo-Carbamazepine Novo-Carbamaz Nu-Carbamazepine Taro-Carbamazepine Taro-Carbamazepine CR Tegretol Tegretol Chewtabs Tegretol CR Generic name product may be available more...

imipenem-cilastatin imipenem-cilastatin
Generic Name: imipenem and cilastatin (i mi PEN em and sye la STAT in) Brand Names: Primaxin IM, Primaxin IV What is imipenem and cilastatin? Imipenem is an antibiotic that fights serious infections caused by bacteria. Cilastatin helps imipenem work more effectively by preventing the bre more...

Liquimat Light Liquimat Light
Generic Name: sulfur topical (SULL fur) Brand Names: Acnotex, Fostril, Liquimat Light, Liquimat Medium, Rezamid, Sulfo-Lo, Sulfoam, Sulforcin, Sulmasque, Sulpho-Lac, Sulpho-Lac Soap What is Liquimat Light (sulfur topical)? Topical sulfur causes drying and peeling of the skin. This allow more...

Mycelex-7 Cream Mycelex-7 Cream
Generic Name: Clotrimazole Vaginal Cream (7 Day) (kloe-TRIM-a-zole) Brand Name: Examples include Gyne-Lotrimin and Mycelex-7Mycelex-7 Cream is used for:Treating vaginal yeast infections and relieving external itching and irritation caused by yeast infections. Mycelex-7 Cream is an antifungal ag more...

Myfortic Delayed-Release Tablets Myfortic Delayed-Release Tablets
Generic Name: Mycophenolic Acid Delayed-Release Tablets (mye-koe-FEN-oh-lik ASS-id) Brand Name: MyforticMyfortic Delayed-Release Tablets decreases your immune system, which may decrease your ability to fight illness or infection. It may also increase the risk of certain types of cancer (eg, lymp more...

Procarbazine Procarbazine
Generic Name: Procarbazine (pro-KAR-ba-zeen) Brand Name: MatulaneProcarbazine is used for:Treating stage III and IV Hodgkin disease along with other medicines. Procarbazine is an antineoplastic. It works by inhibiting protein, RNA, and DNA synthesis, which helps to stop the growth of cancer ce more...