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All about: Carbinoxamine Maleate Extended-Release Capsules

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Generic Name: Carbinoxamine Maleate Extended-Release Capsules and Extended-Release Tablets (kar-bi-NOX-a-meen)
Brand Name: Examples include Histex CT and Histex I/E

Carbinoxamine Maleate Extended-Release Capsules is used for:

Treating allergy symptoms such as runny nose, watery/itchy eyes, rash, or hives. It may also be used for other conditions as determined by your doctor.

Carbinoxamine Maleate Extended-Release Capsules is an antihistamine. It works by blocking the action of histamine, which reduces the symptoms of an allergic reaction.

Do NOT use Carbinoxamine Maleate Extended-Release Capsules if:

  • you are allergic to any ingredient in Carbinoxamine Maleate Extended-Release Capsules
  • you are taking sodium oxybate (GHB) or a monoamine oxidase (MAO) inhibitor (eg, phenelzine)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Carbinoxamine Maleate Extended-Release Capsules:

Some medical conditions may interact with Carbinoxamine Maleate Extended-Release Capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have asthma, glaucoma, difficulty urinating, a stomach or bladder blockage, prostate problems, increased pressure in the eye, an underactive thyroid, heart disease, or high blood pressure

Some MEDICINES MAY INTERACT with Carbinoxamine Maleate Extended-Release Capsules. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Barbiturates (eg, phenobarbital), MAO inhibitors (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because side effects of Carbinoxamine Maleate Extended-Release Capsules may be increased
  • Sodium oxybate (GHB) because side effects, such as an increase in sleep duration and drowsiness leading to unconsciousness or coma, may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Carbinoxamine Maleate Extended-Release Capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Carbinoxamine Maleate Extended-Release Capsules:

Use Carbinoxamine Maleate Extended-Release Capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Carbinoxamine Maleate Extended-Release Capsules may be taken with or without food.
  • Swallow Carbinoxamine Maleate Extended-Release Capsules whole. Do not break, crush, or chew before swallowing.
  • If you miss a dose of Carbinoxamine Maleate Extended-Release Capsules and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Carbinoxamine Maleate Extended-Release Capsules.

Important safety information:

  • Carbinoxamine Maleate Extended-Release Capsules may cause drowsiness or dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Carbinoxamine Maleate Extended-Release Capsules. Using Carbinoxamine Maleate Extended-Release Capsules alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Use Carbinoxamine Maleate Extended-Release Capsules with caution in the ELDERLY because they may be more sensitive to its effects.
  • Use Carbinoxamine Maleate Extended-Release Capsules with extreme caution in CHILDREN younger than 12 years of age. Safety and effectiveness in this age group have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: It is unknown if Carbinoxamine Maleate Extended-Release Capsules can cause harm to the fetus. If you become pregnant while taking Carbinoxamine Maleate Extended-Release Capsules, discuss with your doctor the benefits and risks of using Carbinoxamine Maleate Extended-Release Capsules during pregnancy. It is unknown if Carbinoxamine Maleate Extended-Release Capsules is excreted in breast milk. If you are or will be breast-feeding while you are using Carbinoxamine Maleate Extended-Release Capsules, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Carbinoxamine Maleate Extended-Release Capsules:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Appetite loss; blurred vision; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; headache; heartburn; nausea; nervousness; thickening of mucus in the nose or throat; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include double vision; excitement; frequent urination; hallucinations; loss of consciousness; muscle twitching; seizures; tremor; weakness. In children, symptoms may include abnormal eye movement; abnormal tongue movement; agitation; bizarre behavior; confusion; difficulty urinating; excitation; flushed face; irritability; loss of consciousness; loss of coordination; restlessness; seizures; slurred speech; tiredness; trembling; twitching.

Proper storage of Carbinoxamine Maleate Extended-Release Capsules:

Store Carbinoxamine Maleate Extended-Release Capsules between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Carbinoxamine Maleate Extended-Release Capsules out of the reach of children and away from pets.

General information:

  • If you have any questions about Carbinoxamine Maleate Extended-Release Capsules, please talk with your doctor, pharmacist, or other health care provider.
  • Carbinoxamine Maleate Extended-Release Capsules is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Carbinoxamine Maleate Extended-Release Capsules. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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