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All about: Cardoxin

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Generic Name: digoxin (oral) (di JOX in)
Brand Names: Cardoxin, Digitek, Lanoxicaps, Lanoxin

What is digoxin?

Digoxin helps the heart to beat more strongly and regularly.

Digoxin is used to treat conditions such as congestive heart failure and atrial fibrillation/atrial flutter (types of fast heartbeats).

Digoxin may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about digoxin?

Do not stop taking digoxin suddenly. Stopping suddenly could make your condition worse. Even if you feel better, you need to keep taking this medication to help the heart work properly. Make sure you always have enough digoxin on hand for vacations and holidays.

Ask your doctor to teach you how to monitor your heart rate and at what heart rate you should notify them before taking any more medication.

What should I discuss with my healthcare provider before taking digoxin?

Before taking this medication, tell your doctor if you:

  • have kidney disease;
  • have thyroid disease, or

  • are taking any other heart medication.

You may require a dosage adjustment or special monitoring while taking digoxin.

Digoxin is in the FDA pregnancy category C. This means that it is not known whether digoxin will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment. Digoxin passes into breast milk and may harm a nursing infant. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. If you are over 65 years of age, you may be more likely to experience side effects from digoxin. You may require a dosage adjustment or special monitoring.

How should I take digoxin?

Take digoxin exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Try to take digoxin at the same time every day.

Ask your doctor to teach you how to monitor your heart rate and at what heart rate you should notify them before taking any more medication.

Do not stop taking digoxin suddenly. Stopping suddenly could make your condition worse. Even if you feel better, you may need to keep taking this medication to help the heart work properly. Make sure you always have enough digoxin on hand for vacations and holidays.

Your doctor may want to perform blood tests during treatment with digoxin to monitor the amount of medication in your body.

Store this medication at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose up to 12 hours late. If more than 12 hours have passed, skip the missed dose and take only the next regularly scheduled dose. Do Not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a digoxin overdose include nausea, vomiting, decreased appetite, diarrhea, confusion, seizures, hallucinations, light "halos" around objects, green or yellow vision, fatigue, irregular heartbeats, and abnormally fast or slow heartbeats.

What should I avoid while taking digoxin?

There are no restrictions on food, beverages, or activity while taking digoxin unless otherwise directed by your doctor.

Digoxin side effects

If you experience any of the following serious side effects, stop taking digoxin and seek medical attention or contact your doctor immediately:
  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);

  • a severe headache, fainting, or extreme drowsiness or dizziness;

  • irregular heartbeats;

  • slow heartbeats (fewer than 60 beats per minute);

  • abnormally fast heartbeats;

  • vision changes (e.g., yellow-green or blurred vision);

  • hallucinations; or

  • abnormal or psychotic behavior.

If you experience any of the following less serious side effects, continue to take digoxin and talk to your doctor if you experience

  • decreased appetite and diarrhea;

  • unusual tiredness or weakness;

  • depression;

  • nausea or vomiting;

  • drowsiness or dizziness;

  • decreased sex drive; or

  • enlarged breasts in males.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect digoxin?

Before taking digoxin, tell your doctor if you are taking any of the following medicines:

  • another medication for irregular heartbeats, such as quinidine (Quinidex, Quinora, Cardioquin, others), amiodarone (Cordarone), or propafenone (Rythmol);

  • an antacid or laxative that contains aluminum, magnesium, or kaolin-pectin such as Maalox, Rolaids, Mylanta, Milk of Magnesia, and others;

  • a beta-blocker such as atenolol (Tenormin), propranolol (Inderal), acebutolol (Sectral), metoprolol (Lopressor), carteolol (Cartrol), labetalol (Normodyne, Trandate), or nadolol (Corgard);

  • a calcium channel blocker such as diltiazem (Cardizem, Dilacor XR, Tiazac), amlodipine (Norvasc), felodipine (Plendil), nifedipine (Procardia, Adalat), verapamil (Verelan, Calan, Isoptin, Covera-HS), and others;

  • a cancer chemotherapy drug;

  • a diuretic (water pill) such as hydrochlorothiazide (HCTZ, HydroDiuril, others), chlorothiazide (Diuril), chlorthalidone (Hygroton, Thalitone), furosemide (Lasix), torsemide (Demadex), bumetanide (Bumex), ethacrynic acid (Edecrin), triamterene (Dyrenium, Maxzide, Dyazide), amiloride (Midamor), spironolactone (Aldactone), eplerenone (Inspra), and others;

  • a steroid medicine such as prednisone (Deltasone), methylprednisolone (Medrol, others), prednisolone (Prelone, Pediapred, others), dexamethasone (Decadron), and others;

  • a thyroid medication;

  • alprazolam (Xanax);

  • amphotericin B (Fungizone);

  • cholestyramine (Questran, Prevalite) or colestipol (Colestid);

  • erythromycin (E.E.S., E-Mycin, Eryc, Ery-Tab, PCE, others) or clarithromycin (Biaxin);

  • indomethacin (Indocin);

  • itraconazole (Sporanox);

  • metoclopramide (Reglan);

  • rifampin (Rifadin, Rimactane);

  • sulfasalazine (Azulfidine); or

  • tetracycline (Broadspec, Emtet, Panmycin, Sumycin, Tetracap, others).

You may require a dosage adjustment or special monitoring if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with digoxin or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

Where can I get more information?

  • Your pharmacist has additional information about digoxin written for health professionals that you may read.

What does my medication look like?

Digoxin is available with a prescription under the brand names Lanoxin, Lanoxicaps, Cardoxin, and Digitek. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

  • Lanoxin Pediatric Elixir 0.05 mg/1 mL

  • Lanoxin 0.125 mg--yellow, round, scored tablets

  • Lanoxin 0.250 mg--white, round, scored tablets

  • Lanoxicaps 0.05 mg--red, hard-gelatin capsules

  • Lanoxicaps 0.1 mg--yellow, hard-gelatin capsules

  • Lanoxicaps 0.2 mg--green, hard-gelatin capsules

  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 6.04. Revision Date: 7/30/04 11:10:29 AM.

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