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All about: CellCept Capsules

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Generic Name: Mycophenolate Mofetil Capsules (MYE-koe-FEN-oh-late MOE-feh-til)
Brand Name: CellCept

CellCept Capsules weakens your immune system, which may decrease your ability to fight illness or infection. It may also increase the risk of certain types of cancer (eg, lymphoma). Use CellCept Capsules only under close medical supervision.

CellCept Capsules is used for:

Preventing organ rejection following kidney, liver, or heart transplants. CellCept Capsules is used in combination with other medicines. It may also be used for other conditions as determined by your doctor.

CellCept Capsules is an immunosuppressant. It works by decreasing the activity of certain cells that make up part of the immune system to help reduce the risk of organ transplant rejection.

Do NOT use CellCept Capsules if:

  • you are allergic to any ingredient in CellCept Capsules
  • you are taking azathioprine, cholestyramine, colestipol, or mycophenolic acid

Contact your doctor or health care provider right away if any of these apply to you.

Before using CellCept Capsules:

Some medical conditions may interact with CellCept Capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have stomach or intestinal problems, including ulcers; kidney problems; or a rare hereditary deficiency of hypoxanthine guanine phosphoribosyl-transferase (HGPRT) such as Lesch-Nyhan syndrome or Kelley-Seegmiller syndrome
  • if you are scheduled for a vaccination

Some MEDICINES MAY INTERACT with CellCept Capsules. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Antacids, cholestyramine, colestipol, or iron salts (eg, ferrous sulfate) because they may decrease CellCept Capsules's effectiveness
  • Acyclovir, azathioprine, ganciclovir, mycophenolic acid, or probenecid because they may increase the risk of CellCept Capsules's side effects
  • Oral contraceptives because their effectiveness may be decreased by CellCept Capsules

This may not be a complete list of all interactions that may occur. Ask your health care provider if CellCept Capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use CellCept Capsules:

Use CellCept Capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions. Check the label on the medicine for exact dosing instructions.

  • Take CellCept Capsules on an empty stomach at least 1 hour before or 2 hours after eating.
  • Swallow CellCept Capsules whole. Do not break, crush, chew, or open before swallowing.
  • If capsules are accidentally opened, do not touch or inhale the powder inside. If you get the powder on your skin, wash well with soap and water. If you get it in your eyes, rinse right away with cool tap water.
  • Do not take an antacid that has aluminum or magnesium in it or an iron salt (eg, ferrous fumarate) at the same time as you take CellCept Capsules; space the doses at least 3 to 4 hours apart.
  • If you miss a dose of CellCept Capsules, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use CellCept Capsules.

Important safety information:

  • CellCept Capsules may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use CellCept Capsules with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • CellCept Capsules may increase your risk of developing certain types of cancer (eg, lymphoma, skin cancer). Avoid the sun, sunlamps, or tanning booths until you know how you react to CellCept Capsules. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • CellCept Capsules may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.
  • Do not receive a live vaccine (eg, measles, mumps) while you are taking CellCept Capsules. Talk with your doctor before you receive any vaccine.
  • Hormonal birth control (eg, birth control pills) may not work as well while you are using CellCept Capsules. To prevent pregnancy, use an extra form of birth control (eg, condoms).
  • Proper dental care is important while you are taking CellCept Capsules. Brush and floss your teeth and visit the dentist regularly.
  • Lab tests, including complete blood cell counts, may be performed while you use CellCept Capsules. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • PREGNANCY and BREAST-FEEDING: Do not use CellCept Capsules if you are pregnant. You must have a negative pregnancy test within 1 week before starting CellCept Capsules. To prevent pregnancy, use 2 effective forms of birth control before therapy, during therapy, and for 6 weeks after therapy is completed. The effectiveness of birth control pills may be decreased when taken with CellCept Capsules. Talk with your doctor or pharmacist to determine which forms of effective birth control are right for you. If you think you may be pregnant, contact your doctor right away. It is not known if CellCept Capsules is found in breast milk. Do not breast-feed while taking CellCept Capsules.

Possible side effects of CellCept Capsules:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Acne; anxiety; back pain; constipation; cough; diarrhea; dizziness; headache; incoordination; increased hair growth; indigestion; loss of appetite; mild or moderate stomach pain; muscle cramps; muscle or joint pain; nausea; pain; pain in arms or legs; shakiness; sleeplessness; stomach bloating; vomiting; weakness; weight gain.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in urine; bloody or black stools; changes in heart rhythm; chest pain; enlarged lymph nodes; enlarged stomach; fainting; fever; frequent or infrequent urination; itching; leg pain; night sweats; pounding in the chest; severe vomiting or stomach pain; skin growths; sore throat; swelling of the hands, ankles, or feet; swollen glands; unusual bruising or bleeding; unusual lumps or growths; unusual tiredness; upper respiratory tract infection; urinary tract infection; vomiting blood that looks like coffee grounds; weight loss; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include diarrhea; nausea; vomiting.

Proper storage of CellCept Capsules:

Store CellCept Capsules at 77 degrees F (25 degrees C) in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Keep CellCept Capsules out of the reach of children and away from pets.

General information:

  • If you have any questions about CellCept Capsules, please talk with your doctor, pharmacist, or other health care provider.
  • CellCept Capsules is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about CellCept Capsules. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition
Copyright © 2007 Wolters Kluwer Health, Inc.

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