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All about: Chlorzoxazone

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Generic Name: Chlorzoxazone Tablets (klor-ZOX-uh-zone)
Brand Name: Parafon Forte DSC

Chlorzoxazone is used for:

Treating pain caused by muscle spasms. It is used in combination with rest, physical therapy, and other measures.

Chlorzoxazone is a skeletal muscle relaxant. Exactly how it works is unknown, but it is thought to work in the brain and spinal cord by inhibiting nerve impulses that maintain muscle spasm. This helps you by relieving pain and allowing you to move more easily.

Do NOT use Chlorzoxazone if:

  • you are allergic to any ingredient in Chlorzoxazone
  • you are taking sodium oxybate (eg, GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Chlorzoxazone :

Some medical conditions may interact with Chlorzoxazone . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have liver problems or a blood disease called porphyria

Some MEDICINES MAY INTERACT with Chlorzoxazone . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Sodium oxybate (GHB) because the sedative effects of Chlorzoxazone may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Chlorzoxazone may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Chlorzoxazone :

Use Chlorzoxazone as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Chlorzoxazone by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • If you miss a dose of Chlorzoxazone , take it if it is within 1 hour since the missed dose. If it is more than 1 hour since the missed dose, skip it and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Chlorzoxazone .

Important safety information:

  • Chlorzoxazone may cause dizziness, drowsiness, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Chlorzoxazone with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Chlorzoxazone ; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Chlorzoxazone may discolor the urine orange to purple-red. This is normal and not a cause for concern.
  • Use Chlorzoxazone with caution in the ELDERLY; they may be more sensitive to its effects.
  • Chlorzoxazone should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Chlorzoxazone while you are pregnant. If you are or will be breast-feeding while you use Chlorzoxazone , check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Chlorzoxazone :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; general body discomfort; lightheadedness; nausea; nervousness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; bloody or coffee-ground-like vomit; fever; weight loss; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include diarrhea; difficulty breathing; headache; lightheadedness; nausea; unusual drowsiness or dizziness; vomiting; weak muscles.

Proper storage of Chlorzoxazone :

Store Chlorzoxazone at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store in a tightly closed container away from heat, moisture, and light. Do not store in the bathroom. Keep Chlorzoxazone out of the reach of children and away from pets.

General information:

  • If you have any questions about Chlorzoxazone , please talk with your doctor, pharmacist, or other health care provider.
  • Chlorzoxazone is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Chlorzoxazone . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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