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All about: coagulation factor VIIa injection

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Generic Name: coagulation factor VIIa (injection) (coe ag yoo LAY shun FAK tor )
Brand Names: NovoSeven

What is factor VIIa?

Factor VIIa is a man-made protein that is similar to a natural protein in the body that helps the blood to clot.

Factor VIIa is used to treat or prevent bleeding in people with hemophilia A or hemophilia B, or factor VII deficiency.

Factor VIIa may also be used for purposes other than those listed here.

What is the most important information I should know about factor VIIa?

Do not use this medication if you have ever had an allergic reaction to a clotting factor medication, or if you are allergic to mouse, hamster, or pork proteins.

Before using this medication, tell your doctor if you are allergic to any drugs, or if you have coronary artery disease (hardening of the arteries), a history of stroke or heart attack, or a severe injury or infection.

To be sure this medication is helping your condition, your blood will need to be tested on a regular basis. Do not miss any scheduled visits to your doctor.

Carry an ID card or wear a medical alert bracelet stating that you have a bleeding disorder in case of emergency. Any doctor, dentist, or emergency medical care provider who treats you should know about your condition.

What should I discuss with my healthcare provider before using factor VIIa?

Do not use this medication if you have ever had an allergic reaction to a clotting factor medication, or if you are allergic to mouse, hamster, or pork proteins.

Before using this medication, tell your doctor if you are allergic to any drugs, or if you have:

  • coronary artery disease (hardening of the arteries);

  • a history of stroke or heart attack; or

  • a severe injury or infection.

If you have any of these conditions, you may not be able to use factor VIIa, or you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether factor VIIa passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use factor VIIa?

Factor VIIa is given as an injection through a needle placed into a vein. Your doctor, nurse, or other healthcare provider will give you this injection. You may be given instructions on how to use your injections at home.

Do not use this medicine at home if you do not fully understand how to give the injection and properly dispose of needles and other items used in giving the medicine.

To be sure this medication is helping your condition, your blood will need to be tested on a regular basis. Do not miss any scheduled visits to your doctor.

Carry an ID card or wear a medical alert bracelet stating that you have a bleeding disorder in case of emergency. Any doctor, dentist, or emergency medical care provider who treats you should know about your condition. If you store this medication at home, keep in the refrigerator. Do not freeze. Avoid exposing the medication to sunlight.

What happens if I miss a dose?

Contact your doctor if you miss a dose of this medication.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of factor VIIa is not expected to produce life-threatening symptoms.

What should I avoid while using factor VIIa?

There are no restrictions on food, beverages, or activity while using factor VIIa unless your doctor has told you otherwise.

Factor VIIa side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:
  • fever;

  • continued bleeding after treatment;

  • feeling light-headed, fainting;

  • sudden numbness or weakness, especially on one side of the body;

  • sudden headache, confusion, problems with vision, speech, or balance; or

  • pain or swelling in one or both legs.

Less serious side effects may be more likely to occur, such as:

  • headache;

  • nausea, vomiting;

  • swelling;

  • mild skin rash;

  • joint pain; or

  • pain, redness, or swelling where the medicine was injected.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect factor VIIa?

There may be other drugs that can affect factor VIIa. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

  • Your pharmacist has information about factor VIIa written for health professionals that you may read.

What does my medication look like?

Factor VIIa is available with a prescription under the brand name NovoSeven. Generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 1.05. Revision Date: 11/13/06 3:09:31 PM.

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