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All about: Diazepam Solution

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Generic Name: Diazepam Oral Solution (dye-AZE-uh-pam)
Brand Name: Generics only. No brands available.

Diazepam Solution is used for:

Managing anxiety disorders and for the short-term (less than 4 months) relief of symptoms of anxiety. It may also be used to relieve agitation, shakiness, and hallucinations during alcohol withdrawal, and relieve certain types of muscle pain. It may also be used to treat other conditions as determined by your doctor.

Diazepam Solution is a benzodiazepine. It works by slowing down the movement of chemicals in the brain. This results in a reduction in nervous tension (anxiety) and muscle spasm, and also causes sedation.

Do NOT use Diazepam Solution if:

  • you are allergic to any ingredient in Diazepam Solution
  • you have acute narrow-angle glaucoma, severe liver disease, kidney problems, or a mental state in which contact with reality is lost (psychosis)
  • you are taking an HIV protease inhibitor (eg, ritonavir) or sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Diazepam Solution:

Some medical conditions may interact with Diazepam Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have glaucoma or a predisposition for glaucoma, liver problems, lung problems or chronic obstructive pulmonary disease (COPD), muscle problems, depression, suicidal tendencies, a blood disorder known as porphyria, or a history of alcohol or other substance abuse or dependence

Some MEDICINES MAY INTERACT with Diazepam Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Hydantoins (eg, phenytoin), rifampin, or St. John's wort because they may decrease Diazepam Solution's effectiveness
  • Clozapine, diltiazem, disulfiram, HIV protease inhibitors (eg, ritonavir), narcotic pain relievers (eg, morphine, codeine), nefazodone, omeprazole, sodium oxybate (GHB), or valproic acid because side effects such as increased sedation and confusion may occur
  • Hydantoins (eg, phenytoin), narcotic pain relievers (eg, morphine, codeine), sodium oxybate (GHB), succinylcholine, or tricyclic antidepressants (eg, amitriptyline) because the risk of their side effects may be increased by Diazepam Solution

This may not be a complete list of all interactions that may occur. Ask your health care provider if Diazepam Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Diazepam Solution:

Use Diazepam Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Diazepam Solution by mouth with or without food.
  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • If you miss a dose of Diazepam Solution and you are taking it regularly, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Diazepam Solution.

Important safety information:

  • Diazepam Solution may cause drowsiness, dizziness, blurred vision, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Diazepam Solution with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Diazepam Solution; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • If you are taking Diazepam Solution for seizures, carry an ID card at all times that says you have seizure disorder and you take Diazepam Solution.
  • Lab tests, including liver and kidney function and complete blood cell counts, may be performed while you use Diazepam Solution. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Diazepam Solution should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Diazepam Solution may cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Diazepam Solution while you are pregnant. Diazepam Solution is found in breast milk. Do not breast-feed while using Diazepam Solution.

When used for long periods of time or at high doses, Diazepam Solution may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Diazepam Solution stops working well. Do not take more than prescribed.

Some people who use Diazepam Solution for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction. If you stop taking Diazepam Solution suddenly, you may have WITHDRAWAL symptoms. These may include convulsions, tremor, stomach and muscle cramps, vomiting, or sweating. Do not suddenly stop taking Diazepam Solution without first checking with your doctor.

Possible side effects of Diazepam Solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; dizziness; drowsiness; dry mouth; fatigue; headaches; incoordination; pain, swelling, or redness at the injection site; short-term memory loss; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); anxiety; chest pain; difficulty breathing; difficulty sleeping; difficulty speaking; hallucinations; inability to control urination; increased muscle spasms; interrupted breathing; involuntary eye movement; sleep disturbances; stimulation; sudden rage; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include clumsiness; confusion; deep sleep; loss of consciousness; slow reflexes.

Proper storage of Diazepam Solution:

Store Diazepam Solution at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tight, light-resistant container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Diazepam Solution out of the reach of children and away from pets.

General information:

  • If you have any questions about Diazepam Solution, please talk with your doctor, pharmacist, or other health care provider.
  • Diazepam Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Diazepam Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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