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All about: Ditropan

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Generic Name: oxybutynin (oral) (ox i BYOO ti nin)
Brand Names: Ditropan, Ditropan XL, Urotrol

What is oxybutynin?

Oxybutynin reduces muscle spasms of the bladder and urinary tract.

Oxybutynin is used to treat symptoms of overactive bladder, such as frequent or urgent urination, incontinence (urine leakage), and increased nighttime.

Oxybutynin may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about oxybutynin?

Do not use this medication if you are allergic to oxybutynin, or if you have uncontrolled glaucoma, a blockage in your stomach or intestines, or if you are unable to urinate. Take this medication with a full glass of water. Oxybutynin can cause blurred vision, drowsiness, or dizziness. Be careful if you drive or do anything that requires you to be alert and able to see clearly. Avoid drinking alcohol. It can increase some of the side effects of oxybutynin.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Drink plenty of fluids to keep yourself hydrated while you are taking oxybutynin.

What should I discuss with my healthcare provider before using oxybutynin?

Do not use this medication if you are allergic to oxybutynin, or if you have:
  • untreated or uncontrolled glaucoma;

  • a blockage in your digestive tract (stomach or intestines); or

  • if you have decreased urination or are unable to urinate.

Before using oxybutynin, tell your doctor if you are allergic to any drugs, or if you have:

  • glaucoma;

  • liver disease;

  • myasthenia gravis;

  • kidney disease;

  • an enlarged prostate;

  • an intestinal disorder, such as ulcerative colitis; or

  • a stomach disorder such as gastroesophageal reflux disease (GERD) or slow digestion.

If you have any of these conditions, you may not be able to use oxybutynin, or you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether oxybutynin passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use oxybutynin?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Take this medication with a full glass of water. Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.

Measure the liquid form of oxybutinin with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Try to take this medication at the same time each day.

Store oxybutynin at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of an oxybutynin overdose may include restlessness, tingly feeling, fever, uneven heart rate, vomiting, and urinating less than usual or not at all.

What should I avoid while using oxybutynin?

Oxybutynin can cause blurred vision, drowsiness, or dizziness. Be careful if you drive or do anything that requires you to be alert and able to see clearly. Avoid drinking alcohol. It can increase some of the side effects of oxybutynin.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Drink plenty of fluids to keep yourself hydrated while you are taking oxybutynin.

Avoid using other medicines that make you sleepy (such as cold medicine, pain medication, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by oxybutynin.

Oxybutynin side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using oxybutynin and call your doctor at once if you have any of these serious side effects:
  • fever with hot, dry skin;

  • uneven heart rate;

  • pain, burning, or other difficulty when urinating.

Continue using oxybutynin and talk to your doctor if you have any of these less serious side effects:

  • dizziness, drowsiness, weakness;

  • blurred vision;

  • dry mouth;

  • warmth, tingling, or redness under your skin;

  • nausea, vomiting, stomach pain;

  • constipation or diarrhea;

  • dry eyes;

  • stuffy nose;

  • back pain;

  • feeling restless; or

  • sleep problems (insomnia).

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect oxybutynin?

Before taking oxybutynin, tell your doctor if you are using any of the following drugs:

  • atropine (Donnatal, and others);

  • belladonna;

  • clidinium (Quarzan);

  • dicyclomine (Bentyl);

  • glycopyrrolate (Robinul);

  • hyoscyamine (Anaspaz, Cystospaz, Levsin, and others);

  • mepenzolate (Cantil);

  • methantheline (Provocholine);

  • methscopolamine (Pamine);

  • propantheline (Pro-Banthine);

  • scopolamine (Transderm-Scop); or

  • antibiotics such as clarithromycin (Biaxin), erythromycin (E-Mycin, E.E.S., Ery-Tab, Erythrocin), itraconazole (Sporanox), or ketoconazole (Nizoral).

If you are using any of these drugs, you may not be able to use oxybutynin, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect oxybutynin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

  • Your pharmacist has information about oxybutynin written for health professionals that you may read.

What does my medication look like?

Oxybutynin is available with a prescription generically and under the brand names Ditropan, Ditropan XL, and Urotrol. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

  • Ditropan 5 mg-blue tablets

  • Ditropan XL 5 mg-pale yellow tablets

  • Ditropan XL 10 mg-pink tablets

  • Ditropan Syrup 5 mg/5 mL

  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 4.03. Revision Date: 10/3/06 10:01:32 AM.

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