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All about: EndaCof-PD Drops

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Generic Name: Brompheniramine/Dextromethorphan/Pseudoephedrine Drops (brome-fen-IR-a-meen/dex-troe-meth-OR-fan/sue-do-eh-FED-rin)
Brand Name: Examples include EndaCof-PD and PediaHist DM

EndaCof-PD Drops is used for:

Relieving symptoms of sinus congestion, runny nose, sneezing, and cough due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.

EndaCof-PD Drops is a decongestant, antihistamine, and cough suppressant combination. It works by constricting blood vessels and reducing swelling in the nasal passages. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing while the cough suppressant works in the brain to help decrease the cough reflex to reduce a dry cough.

Do NOT use EndaCof-PD Drops if:

  • you are allergic to any ingredient in EndaCof-PD Drops
  • you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems
  • you are unable to urinate or are having an asthma attack
  • you take sodium oxybate (GHB) or if you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using EndaCof-PD Drops:

Some medical conditions may interact with EndaCof-PD Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a fast, slow, or irregular heartbeat
  • if you have a history of adrenal gland problems (eg, adrenal gland tumor); heart problems; high blood pressure; diabetes; heart blood vessel problems; stroke; glaucoma; a blockage of your stomach, bladder, or intestines; ulcers; trouble urinating; an enlarged prostate or other prostate problems; seizures; or an overactive thyroid
  • if you have a history of asthma, chronic cough, lung problems (eg, chronic bronchitis, emphysema), chronic obstructive pulmonary disease (COPD), or if your cough occurs with large amounts of mucus

Some MEDICINES MAY INTERACT with EndaCof-PD Drops. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Beta-blockers (eg, propranolol), COMT inhibitors (eg, tolcapone), furazolidone, indomethacin, MAOIs (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of EndaCof-PD Drops's side effects
  • Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
  • Bromocriptine or hydantoins (eg, phenytoin) because the risk of their side effects may be increased by EndaCof-PD Drops
  • Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by EndaCof-PD Drops

This may not be a complete list of all interactions that may occur. Ask your health care provider if EndaCof-PD Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use EndaCof-PD Drops:

Use EndaCof-PD Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take EndaCof-PD Drops by mouth with or without food.
  • Use the dropper that comes with EndaCof-PD Drops to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • If you miss a dose of EndaCof-PD Drops, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use EndaCof-PD Drops.

Important safety information:

  • EndaCof-PD Drops may cause dizziness, drowsiness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use EndaCof-PD Drops with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not take diet or appetite control medicines while you are taking EndaCof-PD Drops without checking with you doctor.
  • EndaCof-PD Drops has pseudoephedrine in it. Before you start any new medicine, check the label to see if it has pseudoephedrine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
  • Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • If your symptoms do not get better within 5 to 7 days or if they get worse, check with your doctor.
  • EndaCof-PD Drops may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to EndaCof-PD Drops. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • If you are scheduled for allergy skin testing, do not take EndaCof-PD Drops for several days before the test because it may decrease your response to the skin tests.
  • Tell your doctor or dentist that you take EndaCof-PD Drops before you receive any medical or dental care, emergency care, or surgery.
  • Use EndaCof-PD Drops with caution in the ELDERLY; they may be more sensitive to its effects.
  • Caution is advised when using EndaCof-PD Drops in CHILDREN; they may be more sensitive to its effects.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using EndaCof-PD Drops while you are pregnant. It is not known if EndaCof-PD Drops is found in breast milk. Do not breast-feed while taking EndaCof-PD Drops.

Possible side effects of EndaCof-PD Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; trouble sleeping; vision changes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of EndaCof-PD Drops:

Store EndaCof-PD Drops at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep EndaCof-PD Drops out of the reach of children and away from pets.

General information:

  • If you have any questions about EndaCof-PD Drops, please talk with your doctor, pharmacist, or other health care provider.
  • EndaCof-PD Drops is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about EndaCof-PD Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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