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All about: Erythromycin Solution

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Generic Name: Erythromycin Topical Solution (eh-RITH-roe-MYE-sin)
Brand Name: Eryderm

Erythromycin Solution is used for:

Treating severe acne. It may also be used for other conditions as determined by your doctor.

Erythromycin Solution is a topical macrolide antibiotic that is thought to improve acne by slowing the growth of bacteria on the skin, which causes acne.

Do NOT use Erythromycin Solution if:

  • you are allergic to any ingredient in Erythromycin Solution

Contact your doctor or health care provider right away if any of these apply to you.

Before using Erythromycin Solution:

Some medical conditions may interact with Erythromycin Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have liver disease or you have a blood disorder called porphyria

Some MEDICINES MAY INTERACT with Erythromycin Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Arsenic, cisapride, diltiazem, disopyramide, dofetilide, HIV protease inhibitors (eg, ritonavir), imidazoles (eg, ketoconazole), pimozide, QT-prolonging agents (eg, quinidine, sotalol), quinolones (eg, ciprofloxacin), streptogramins (eg, quinupristin/dalfopristin), or verapamil because side effects, such as heart toxicity or irregular heartbeat, may occur
  • Anticoagulants (eg, warfarin), aldosterone blockers (eg, spironolactone), benzodiazepines (eg, alprazolam), buspirone, carbamazepine, cilostazol, corticosteroids (eg, hydrocortisone), cyclosporine, digoxin, ergot alkaloids (eg, ergotamine), felodipine, H1 antagonists (eg, astemizole, terfenadine), HMG-CoA reductase inhibitors (eg, simvastatin), imatinib, macrolide immunosuppressants (eg, tacrolimus), midazolam, phosphodiesterase type 5 inhibitors (eg, sildenafil), rifampin, sumatriptan, theophyllines, or vinca alkaloids (eg, vincristine) because the risk of their side effects may be increased by Erythromycin Solution

This may not be a complete list of all interactions that may occur. Ask your health care provider if Erythromycin Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Erythromycin Solution:

Use Erythromycin Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions. Check the label on the medicine for exact dosing instructions.

  • Wash affected areas with soap and warm water. Rinse well and pat dry before applying the medicine.
  • To use the applicator, hold the bottle upside down and moisten applicator by pressing once on the applicator surface with a clean fingertip. Then apply Erythromycin Solution to the affected area using a dabbing motion. Use enough medicine to cover the entire affected area.
  • Wash your hands immediately after applying Erythromycin Solution.
  • Erythromycin Solution works best if it is used at the same time each day.
  • To clear up your infection completely, take Erythromycin Solution for the full course of treatment. Keep taking it even if you feel better in a few days.
  • If you miss a dose of Erythromycin Solution, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Erythromycin Solution.

Important safety information:

  • Erythromycin Solution is for external use only. Avoid contact with the eyes, nose, mouth, and other mucous membranes. If you get Erythromycin Solution in your eyes, immediately wash them out with cool tap water.
  • Talk with your doctor before you use any other medicines or cleansers on your skin.
  • Once you begin using Erythromycin Solution, it may take 3 to 8 weeks before you begin to see improvement.
  • Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
  • Be sure to use Erythromycin Solution for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Long-term or repeated use of this medicine may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Erythromycin Solution is flammable. Do not store or use near an open flame or while smoking.
  • Erythromycin Solution should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Erythromycin Solution while you are pregnant. Erythromycin Solution is found in breast milk. If you are or will be breast-feeding while you use Erythromycin Solution, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Erythromycin Solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Burning; dryness; mild stinging; peeling.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; itching, burning, tenderness, or redness of skin; severe diarrhea; stomach cramps/pain.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Erythromycin Solution may be harmful if swallowed.

Proper storage of Erythromycin Solution:

Store Erythromycin Solution at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly-closed container. Store away from heat and light. Keep Erythromycin Solution out of the reach of children and away from pets.

General information:

  • If you have any questions about Erythromycin Solution, please talk with your doctor, pharmacist, or other health care provider.
  • Erythromycin Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Erythromycin Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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