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All about: Ethezyme Ointment

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Generic Name: Papain/Urea Ointment (pap-ANE/you-REE-ah)
Brand Name: Examples include Accuzyme and Ethezyme

Ethezyme Ointment is used for:

Removing dead tissue and thinning the pus in lesions such as ulcers, burns, wounds, and carbuncles.

Ethezyme Ointment is a debriding agent. It works by helping the breakdown of dead skin and pus, which helps improve the recovery time of open wounds.

Do NOT use Ethezyme Ointment if:

  • you are allergic to any ingredient in Ethezyme Ointment

Contact your doctor or health care provider right away if any of these apply to you.

Before using Ethezyme Ointment:

Some medical conditions may interact with Ethezyme Ointment. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Ethezyme Ointment. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Medicines containing silver, lead, or mercury because they may decrease Ethezyme Ointment's effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Ethezyme Ointment may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Ethezyme Ointment:

Use Ethezyme Ointment as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Ethezyme Ointment is for external use only.
  • Before each use of Ethezyme Ointment, clean the affected area with saline or another mild wound cleansing solution. Do not use hydrogen peroxide.
  • Apply Ethezyme Ointment directly to the lesion, cover with appropriate dressing (eg, bandages), and secure into place. Wash the lesion each time the dressing is changed.
  • Change wound dressings according to the schedule set by your doctor.
  • If irritation occurs, talk with your doctor about changing the dressings more often.
  • If you miss a dose of Ethezyme Ointment, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Ethezyme Ointment.

Important safety information:

  • This medicine is for external use only. Do not get it in the eyes or mouth. If you get Ethezyme Ointment in the eyes, rinse them immediately with a generous amount of cool water.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Ethezyme Ointment while you are pregnant. It is not known if Ethezyme Ointment is found in breast milk. If you are or will be breast-feeding while you use Ethezyme Ointment, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Ethezyme Ointment:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Mild skin irritation; temporary burning sensation.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Ethezyme Ointment:

Store Ethezyme Ointment in a cool place, between 46 and 59 degrees F (8 and 15 degrees C). Do not refrigerate. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Ethezyme Ointment out of the reach of children and away from pets.

General information:

  • If you have any questions about Ethezyme Ointment, please talk with your doctor, pharmacist, or other health care provider.
  • Ethezyme Ointment is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Ethezyme Ointment. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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